Wednesday, April 30, 2008

Indonesian Lawmakers Call For NAMRU-2 Probe

 

# 1935

 

 

 

A hat tip to Crof on Crofsblog for picking up this story from the Jakarta Post on increasing calls by the Indonesian House of Representatives to investigate the operations of NAMRU-2.

 

In what must make for good politics in Indonesia, lawmakers are continuing to suggest through innuendo alone that our NAMRU-2  lab personnel have been conducting spying operations in their country. Calls for an investigation are increasing.

 

One has to hope that all of this sound and fury is for show, and that cooler heads are working towards a diplomatic solution.  

 

The stakes are simply too high for rhetoric to rule.

 

 

 

Wednesday, April 30, 2008  2:33 PM

 

House calls for inquiry into U.S. lab

Abdul Khalik and Suherdjoko ,  The Jakarta Post ,  Jakarta, Semarang   |  Tue, 04/29/2008 12:52 PM  |  National

 

Members of the House of Representatives have moved to establish a special task force to investigate U.S. Naval Medical Research Unit No. 2 (Namru-2).

 

The Indonesian Democratic Party of Struggle (PDI-P) proposed the interfaction fact-finding team because of allegations the U.S. laboratory is engaging in espionage and the lack of apparent benefits to Indonesia from their research, said senior PDI-P lawmaker Sidarto Danusubroto.

 

"We propose the House form a task force to investigate the lab to reassure the public that it isn't spying on us and that it really benefits the country," he told The Jakarta Post.

 

Sidarto, a member of the House's Commission I on security, defense and foreign affairs, said the team would urge the laboratory to be transparent in its operations.

 

Lawmaker Hakim Sorimuda Pohan of President Susilo Bambang Yudhoyono's Democratic Party supported the idea, saying Indonesian scientists could take over the work of the laboratory's researchers.

 

"We will summon the health minister to discuss the issue further. I see no need for the lab to continue operating here," he told the Post.

 

Indonesia and the United States are now negotiating a new memorandum of understanding (MOU) to extend the operation of Namru-2. The previous agreement expired in 2005.

 

Indonesia offered last week to grant diplomatic immunity to only two U.S. officials at Namru-2 and demanded the laboratory become more transparent.

 

In a response through its embassy, the United States insisted all 19 of its citizens working at Namru-2 be given diplomatic immunity.

 

The United States denied the laboratory lacked transparency.

 

Demands for Namru-2 to be closed down have been mounting in recent weeks.

(Cont. )

N. Korea Forms Bird Flu Planning Committee

 

#1934

 

It isn't often that we get bird flu news out of North Korea.  With the exception of a reported outbreak in 2005, North Korea has been pretty much silent on the issue.

 

Today South Korean news sources are reporting an announcement, monitored from a North Korean Television broadcast, that an `emergency state quarantine committee had been formed to work out national plans to prevent a possible outbreak of bird flu'.

 

Here is how Yonhap News is reporting the story.

 

 

 

 

 

 

N.K. forms emergency office to prevent bird flu outbreak


SEOUL, April 30 (Yonhap) -- North Korea has established an emergency state committee overseeing efforts to prevent the possible spread of bird flu, which has inflicted serious damage in South Korea, according to North Korean television Wednesday.


 

"The emergency state quarantine committee was formed to work out national plans to prevent a possible outbreak of bird flu," the North's Central TV said.

 

The move came at the instruction of North Korean leader Kim Jong-il, the report added.

 

The North has banned South Korean poultry products and eggs from the joint industrial complex in Kaesong, just north of the inter-Korean border, since Saturday to prevent the cross-border spread of the disease.

 

Over 5 million birds have been culled in South Korea since the first outbreak was reported in Gimje, North Jeolla Province, earlier this month.

 

The Central TV said the committee is orchestrating provincial administrations' sanitation measures, livestock quarantine as well as other programs to prevent bird flu. The report, however, did not mention when the committee was organized.

 

North Korea destroyed 210,000 chickens during the bird flu outbreak in 2005. It has since actively taken part in anti-epidemic programs offered by the World Health Organization.

Reminder: HHS Webcast Today

 

#1933

 

 

The third in a series of 3 Webcasts conducted by the HHS will air today at 2pm ET.  The focus will be on the impact of school closings in a pandemic.  The two previous webcasts have been archived and may be viewed  here, and here.

 

Here is how the HHS describes the event.

 

 

 

Webcast Series on Pandemic Influenza

 

Please join us for a live discussion to help state planners in the next round of pandemic influenza planning. No registration is required. Email your questions for the webcast panelists during the program to hhsstudio@hhs.gov. Please include your first name, state and town.

Webinar Video Player: Join Us Wednesday, April 30th at 2 p.m. ET

 

The video will stream in Windows Media format. Please note you will need a Windows media player installed on your computer’s browser in order to view the live video stream. If you are unable to view this live stream in the Windows media format you can view the Flash video-on-demand of the event that will be made available May 5th.

 

This webcast will cover the impact of implementing the community mitigation intervention of dismissal of students/school closures. It will provide the opportunity for a live question-and-answer session with these Federal specialists: 

  • Francisco Averhoff, MD, MPH, Centers for Disease Control and Prevention 
  • Camille Welborn, U.S. Department of Education 
  • Barbara Bingham, U.S. Department of Labor 
  • Brenda Lisi, U.S. Department of Agriculture

 

More information on pandemic planning as it relates to schools, educators and administrators can be found on the Department of Education's Emergency Planning page

 

Earlier webinars on the State planning and assessment process aired on March 13 and April 2.

 

The pandemic influenza planning webcasts are brought to you by the U.S. Department of Health and Human Services

Tuesday, April 29, 2008

Indonesia Reports New Bird Flu Fatality

 

# 1932

 

 

The month of April has been a relatively quiet one in Indonesia on the bird flu front.   The last news of human infections we received was summarized on April 2nd by this WHO Summary

 

 

The Ministry of Health of Indonesia has announced three new cases of human H5N1 avian influenza infection. The cases are not linked epidemiologically. The first is a 15-year-old male student from Subang District, West Java Province who developed symptoms on 19 March, was hospitalized on 22 March and died on 26 March .

 

The second case is an 11-year-old female student from Bekasi City, West Java Province who developed symptoms on 19 March, was hospitalized on 23 March and died on 28 March.

 

The third case is a 21-month-old female from Bukit Tinggi, West Sumatra Province who developed symptoms on 17 March, and was hospitalized on 22 March. She is presently recovering in hospital.

 

The source of infection for all three cases is still under investigation.

 

Of the 132 cases confirmed to date in Indonesia, 107 have been fatal.

 

Since then we've heard virtually nothing out of Indonesia about bird flu other than the reports on the Bali pandemic exercise.    

 

Today we get word that a 3-year-old boy died on April 23rd, and that he has tested positive for the H5N1 virus.  

 

The article below inaccurately describes this as Indonesia's 108th confirm human case.  It is not.  This is the 108th confirmed fatality.

 

This should make the 133rd confirmed human case.

 

 

 

 

April 29, 2008

Indon boy dies of bird flu

JAKARTA - A THREE-YEAR-OLD boy from Indonesia's main island of Java has died from bird flu, pushing the country's total confirmed human cases to 108, a health ministry official said on Tuesday.

 

Lily Sulistyowati, the ministry's spokeswoman, said in a statement that the boy from Manyaran village, Central Java, died on April 23 after suffering from respiratory problems.

 

Several chickens had suddenly died in the neighbourhood where the boy lived, Sulistyowati said, adding the boy had had contact with the birds.

South Korean Investigating New Outbreak

 

# 1931

 

 

A worrisome turn of events if this outbreak is confirmed (there are other causes of bird deaths besides avian flu).  Ulsan city is located in the southeast region of the country that thus far has remained unscathed by the bird flu virus.

 

Location map

Map of South Korea highlighting the city

 

 

 

This report from Radio Australia.

 

 

South Korea reports new bird flu outbreak

 

 

South Korea, grappling its worst outbreak of bird flu, has reported another suspected outbreak of the virus at a chicken farm in Ulsan City.

 


If confirmed, it would be the first in the southeast of the country,.


South Korea previously confirmed 20 cases of the H5N1 strain in poultry in less than one month, despite having killed more than five million birds.

 

No human deaths from the disease have been reported so far.


South Korea had to kill almost five and a half million birds during its first bird flu outbreak between late 2003 and early 2004.

 


The second outbreak in 2006-2007 saw about half that number culled.

Nepal Watches India, Worries

 

# 1930

 

 

 

The Chicken's Neck is the strip of Indian territory is shown in red.

 

The Chicken's Neck is the strip of Indian territory is shown in red.

 

 

 

 

While Nepal has yet to report an outbreak of bird flu, it shares a long, open border with India, and is separated from Bangladesh by a thin (20km-40km) strip of India commonly called the `chicken's neck'.

 

Worried about the spread of the disease in both of these neighboring countries, Nepal has raised their alert level and is testing some farms along the border.

 

This from Reuters.

 

 

 

 

 

 

Nepal on flu alert, tests poultry on India border

 

Tue Apr 29, 1:23 AM ET

 

KATHMANDU (Reuters) - Nepal has issued a bird flu alert and is testing poultry along the border with India, where the virus rages despite the culling of tens of thousands of chickens since 2006, officials said.

 

Nepal, which has not reported any bird flu cases, banned the import of poultry from India in January.

 

But it shares an open border with the Indian state of West Bengal which has reported repeated outbreaks of bird flu.

 

<snip>

 

Nepal has declared six eastern districts "high-risk zones" and intensified vigil on farm and backyard poultry. Ninety chicken samples were being tested.

Toronto City Council Approves 1.5M Purchase Of Tamiflu

 

# 1929

 

 

In a bold move the City Council of Toronto voted today to purchase enough tamiflu to treat up 13,000 municipal employees in a pandemic.  With 24,000 employees, plus thousands more police, firefighters, and transit drivers, questions as to who will receive this antiviral have yet to be resolved.

 

This from the National Post.

 

 

 

 

City to buy $1.5M worth of Tamiflu

Staff to be treated in event of flu pandemic

Allison Hanes, National Post 

Published: Tuesday, April 29, 2008

 

Toronto city council signed off yesterday on the purchase of $1.5-million worth of antiviral medication to treat up to 13,000 municipal employees in the case of a possible flu pandemic, despite budgetary constraints and amid lingering questions over who will be eligible to receive it and how.

 

Council was told Toronto is the only major Canadian city stockpiling its own supply of influenza-fighting drugs for its employees after learning from the SARS epidemic.

 

The decision follows the recommendation of Toronto's medical officer of health, who said Toronto must act now given the long lag time involved in acquiring Tamiflu, which is not a vaccine but one of the key drugs expected to be crucial in the event of an outbreak.

 

Under questioning from councillors as to the necessity of acting so urgently, David McKeown acknowledged he can't predict if or when a flu pandemic will strike.

 

"I believe it is a prudent measure to take for an event that is highly likely to occur," Dr. McKeown said, citing research that shows a major -- often lethal--flu virus sweeps the globe every 30 to 40 years.

 

Council also decided to spend $606,000 to properly store its drug supply in a warehouse.

 

In total, Toronto could spend up to $5-million stocking drugs to keep the city running in the event of a devastating flu virus.

 

Although a majority of council voted in favour of procuring the pharmaceuticals, questions swirled yesterday over who among Toronto's 24,000 municipal employees, plus thousands more police, firefighters and transit drivers, would receive the medication and how it would be dispensed.

Japan Confirms Swans Infected With H5N1

 

# 1928

 

 

This confirmation was pretty much expected, since yesterday they stated these swans tested positive for an H5 virus. 

 

While there are no chicken farms within 10km (6 miles) of where these birds were found, authorities will inspect farms on Wednesday and Thursday at 15 farms within a radius of 30 km (19 miles).

 

This report from Reuters.

 

 

 

 

 

Japan confirms H5N1 bird flu strain in swans

Tue Apr 29, 2008 4:52am EDT

 

TOKYO (Reuters) - Japan on Tuesday confirmed four swans found last week were infected with the H5N1 strain of bird flu.

 

It was the first case of bird flu in Japan since March 2007 when the highly virulent H5N1 strain was found in a wild bird in Kumamoto prefecture on Japan's southern Kyushu island.

 

The swans, three of which had died, were found on the shores of Lake Towada in northern Akita prefecture on April 21, the prefectural government said.

 

Inspectors had initially detected the H5 subtype of bird flu in the dead swans and conducted further tests, the local government said on Monday.

 

Japan has been stepping up checks of birds after a series of bird flu outbreaks in South Korea over the past month.

Monday, April 28, 2008

Florida's Pandemic Planning Toolkit for AgriBusiness

 

# 1927

 

 

Today the State of Florida's Agriculture Department released an easy to read, 28 page, pandemic planning toolkit for businesses involved in the production, delivery, or sale of food.

 

While produced for the food and agriculture sector, this guide would serve any business as a reasonable starting point for creating a pandemic plan.  

 

The PDF document can be downloaded  HERE.

 

The State of Florida's Agriculture Department's Press release follows, and then I'll have comments about the toolkit.

 

 

 

Department Press Release

04-28-2008

Terence McElroy
 (850) 488-3022
mcelrot@doacs.state.fl.us

 

Bronson Unveils Pandemic Flu Planning Kit For Businesses
Involved In The Production, Delivery Or Sale Of Food

 

TALLAHASSEE – Florida Agriculture and Consumer Services Commissioner Charles H. Bronson today announced that his department has developed a planning guide to assist small agribusinesses prepare for and respond to a pandemic influenza outbreak.

 

Called the “Pandemic Influenza Agriculture Planning Tool Kit,” the 28-page guide walks business owners through various steps in planning and responding to such an outbreak, including accounting for the whereabouts of employees, storing emergency supplies and establishing communications with key contacts during the emergency. It can be accessed on the Florida Department of Agriculture and Consumer Services’ website at www.doacs.state.fl.us.

 

“It is vital that businesses, especially ones involved in the production or delivery of food, have a plan so they can continue operating and feeding our citizens during a pandemic flu outbreak or an emergency of any kind,” Bronson said. “We developed this guidebook because it occurred to us at recent workshops that most small agribusinesses lack the financial resources or personnel to develop preparedness plans of their own despite the critical role they play in the production and delivery of our food supply.”

 

Bronson said the guidebook can be altered or tailored to address the needs of most agricultural operations and encourages such businesses to review the tool kit.

 

Pandemic influenza is a global disease outbreak in which a new influenza virus emerges - a virus against which people have little, if any, immunity and one for which there is no vaccine. The disease spreads easily from person to person, causing serious illnesses, and can quickly move across an entire country or continent.

 

Such a disease would cause mass absenteeism, put a major strain on a nation’s health care system and disrupt untold vital services

 

 

This toolkit is an excellent `first exposure' to pandemic planning for most small to medium sized businesses.  It works very hard not to overwhelm or frighten its intended audience, and yet it does hit the highlights of the things that most businesses need to be considering in a pandemic plan.

 

In fairness, it does gloss over  some of the `worst case scenarios' by simply stating that we can't know in advance how bad the next pandemic will be.  Here is how they address the issue.

 

 

The number of hospitalizations and deaths will depend on the virulence of the pandemic virus. Estimates differ about ten-fold between more and less severe scenarios. Per HHS planning guidance, Florida is planning for a severe influenza pandemic similar to 1918, as compared to a moderate pandemic similar to 1957, 1968. Either one could happen.

 

Risk groups for severe and fatal infection cannot be predicted with certainty but are likely to include infants, elderly, pregnant woman, and persons with chronic medical conditions.

 

 

The toolkit, really a series of checklists, gives individuals and businesses a starting point to begin organizing their pandemic plans. 

 

 As an example, for individuals, here is the advice they give to prepare for a pandemic:

 

  • Store a supply of water and food. During a pandemic, if you cannot get to a store, or if stores are out of supplies, it will be important for you to have extra supplies on hand. This can be useful in other types of emergencies, such as power outages and disasters (2-3 weeks is recommended).

 

  • Periodically check your regular prescription drugs to ensure a continuous supply in your home.

 

  • Have any nonprescription drugs and other health supplies on hand, including pain relievers, stomach remedies, cough and cold medicines, fluids with electrolytes, and vitamins (30-day supply is recommended).

 

  • Talk with family members and loved ones about how they would be cared for if they got sick, or what will be needed to care for them in your home.

 

  • Volunteer with local groups to prepare and assist with emergency response.

 

  • Get involved in your community as it works to prepare for an influenza pandemic.

 

  

The toolkit then gives a very basic checklist of the types of food, and medical supplies, to stockpile.    No doubt most people will need to augment these checklists, but they provide a good starting point.

 

The next section covers planning for a pandemic's impact on your business.   This area offers such sage advice as:

 

 

  • Identify a pandemic coordinator and/or team with defined roles and responsibilities for preparedness and response planning. The planning process should include input from labor representatives.


  • Identify essential employees and other critical inputs (e.g., raw materials, suppliers, sub-contractor services/products, and logistics) required to maintain business operations by location and function during a pandemic.


  • Train and prepare ancillary workforce (e.g., contractors, employees in other job titles/descriptions, retirees).


  • Cross-train your employees. Figure out what jobs need to be trained ahead of time and jobs that can be trained at the time, time critical jobs, i.e. specialty crop harvesting, coordination with other agribusinesse at harvest time.

 

Again, not rocket science, but crucial steps that most businesses have yet to undertake.  

 

The toolkits go on to cover the impact of a pandemic on employees and customers, and what policies a business may need to establish for operating during a pandemic.

 

The last ten pages are basically a primer on pandemics, and how to protect yourself and others from infection.  Covering your cough, washing your hands, staying home when you are sick, and social distancing.

 

The value of this toolkit is that it serves as an easy introduction to  pandemic planning.  It won't frighten the reader unduly, but it should impress upon most that planning is essential.  Since it carries the seal of approval of the State of Florida's Agriculture Commission, it should carry some weight in the business community.

 

For most businesses, this is a good starting point. 

HHS Webcast On Wednesday April 30th

 

# 1926

 


On Wednesday, the HHS will conduct the third in a series of interactive webcasts on pandemic influenza.   The public is invited to submit questions. 

 

The Flu Wiki has an ongoing thread about this upcoming program HERE. A hat tip to Kobie for starting this thread.

 

Here is the announcement from the HHS page.

 

 

 

Webcast Series on Pandemic Influenza

Please join us for a live discussion to help state planners in the next round of pandemic influenza planning. No registration is required. Email your questions for the webcast panelists during the program to hhsstudio@hhs.gov. Please include your first name, state and town.

 

Webinar Video Player: Join Us Wednesday, April 30th at 2 p.m. ET

 

The video will stream in Windows Media format. Please note you will need a Windows media player installed on your computer’s browser in order to view the live video stream. If you are unable to view this live stream in the Windows media format you can view the Flash video-on-demand of the event that will be made available May 5th.

 

This webcast will cover the impact of implementing the community mitigation intervention of dismissal of students/school closures. It will provide the opportunity for a live question-and-answer session with these Federal specialists: 

  • Francisco Averhoff, MD, MPH, Centers for Disease Control and Prevention 
  • Camille Welborn, U.S. Department of Education 
  • Barbara Bingham, U.S. Department of Labor 
  • Brenda Lisi, U.S. Department of Agriculture

 

More information on pandemic planning as it relates to schools, educators and administrators can be found on the Department of Education's Emergency Planning page

 

Earlier webinars on the State planning and assessment process aired on March 13 and April 2.

 

The pandemic influenza planning webcasts are brought to you by the U.S. Department of Health and Human Services. 

Third Vietnamese Province Hit By Bird Flu

 

# 1925

 

 

The number of Vietnamese provinces currently reporting bird flu is only three, a far cry from the 18 that were battling the virus a little less than a year ago.  

 

This report from Xinhua News.    

 

 

 

Bird flu hits one more Vietnamese locality

www.chinaview.cn 2008-04-28 11:57:27
 

    HANOI, April 28 (Xinhua) -- Bird flu has recently hit Vietnam's northern Son La province, raising the total number of localities currently affected by the disease to three, according to local newspaper Young People reported Monday.

 

    Specimens from 95 died chickens and ducks out of a flock of 135 fowls raised by a household in the province's Son La town were tested positive to bird flu virus strain H5N1, the paper quoted the country's Department of Animal Health as reporting.

 

    The provincial veterinary agency has isolated the outbreak, and disinfected the affected farm to prevent the disease's spread.

 

    Now, bird flu is hitting Son La, and Tien Giang province and Can Tho City in the southern region, said the department.

 

    Bird flu outbreaks in Vietnam, starting in December 2003, have killed and led to the forced culling of dozens of millions of fowls in the country.

US Orders More Pre-Pandemic Vaccine

 

# 1924

 

 

It was announced this morning that the US government has ordered enough bulk antigen from Sanofi-Aventis to produce roughly 38.5 million doses of pre-pandemic vaccine. 

 

The 192.5 million dollar order is in addition to the 126.9 million dollar order from Sanofi-Aventis last year.   This antigen will be based on Clade 2.2 (A/Barheaded goose/Qinghai Lake/01/2005)of the H5N1 virus, seen in migrating birds.

 

A pre-pandemic vaccine, based on an existing clade of the H5N1 virus, is hoped to provide partial protection during a pandemic.  How much protection is unknown.  Much depends on how much the pandemic virus differs from its earlier incarnations.

 

Since it requires 2 doses of the vaccine, 28 days apart, this order will cover roughly 19.25 million people.   In 2007 the United States purchased 126 million dollars worth of prepandemic vaccine based on Clade 2.0 of the virus.  Smaller amounts of a clade 1 vaccine were produced prior to 2007.

 

This new order should bring the US stockpile up to roughly 32 million courses of vaccine, albeit split between 2 or more clades.   A delivery date for this new vaccine antigen did not appear in the news release.

 

 

 

 

 

 

2008-04-28 07:39
Sanofi-Aventis wins new $192.5 mln order for avian flu vaccine from U.S. govt

 

PARIS (Thomson Financial) - Sanofi Pasteur, the vaccines division of Sanofi-Aventis, said it has received an order worth $192.5 million from the U.S. government for vaccines against a new strain of avian influenza.

 

Sanofi Pasteur said it will receive from the U.S. Department of Health and Human Services (HHS) a payment of $192.5 million, to be booked in the second quarter of 2008, for supplying H5N1 bulk vaccine antigen that will produce approximately 38.5 million doses of vaccine.

Bird Flu Found In 4 Japanese Swans

 

# 1923

 

 

 

Map of Japan with Akita highlighted

 

 

 

While few details are available at this time, and the exact strain of bird flu has yet to be determined, officials are saying that they've discovered `bird flu' in 3 dead and 1 weakening swan at Lake Towada in the Akita Prefecture.

 

Highlighted in the map above, Akita Prefecture is a popular tourist destination in Japan.   Lake Towada is a caldera (crater) lake, and is about 450 km from Tokyo. 

 

 

 

 
 

 

 

 

 

 

Bird flu virus found in 3 dead swans in Akita

Monday 28th April, 04:59 PM JST

AKITA —

The avian influenza virus has been detected in three dead swans and one weakening one along Lake Towada in Kosaka, Akita Prefecture, the Akita prefectural government said Monday. The Akita government said it has asked the state to determine whether the virus belongs to the deadly H5N1 strain.


Local officials said they have yet to find a link between the virus and the deaths of the swans. The officials said they see a low possibility of the virus damaging human health as there have been no reports of many birds or animals dying in the northeastern Japan prefecture.

Sunday, April 27, 2008

IOM Report Questions Size and Intent Of US Tamiflu Stockpile

 

#1922

 

 

The Institute of Medicine (IOM) is a advisory group setup to provide our government with "independent, objective, and evidenced based' advice on medical issues.  The IOM was established in 1970 under the charter of the National Academy of Sciences.

 

On Friday this group released a report on our nation's antiviral stockpile, calling for clarification of how it will be used, and strongly suggesting that the quantity on hand will be inadequate.

 

Here is an excerpt from the CIDRAP (Center for Infectious Disease Research & Policy) reporting on the story, follow the link to read the entire article.

 

 

 

IOM: US likely to need bigger antiviral stockpile

 

Robert Roos  News Editor

 

Apr 25, 2008 (CIDRAP News) – The US government will need to expand its stockpile of antiviral drugs if the goal is to have enough doses to treat all patients and provide preventive treatment for some others at risk in an influenza pandemic, the Institute of Medicine (IOM) says in a report issued today.

 

An IOM committee of experts asserts that the government needs to clarify its goals concerning antiviral use in a pandemic, because current planning documents are fuzzy on prophylactic use of the drugs.

 

The nation currently has about 71 million treatment courses of antivirals in federal and state stockpiles, with a goal of 81 million courses, the report says. But in a pandemic, it might take more than twice that amount to treat sick patients and offer preventive doses to people at risk for exposure on the job, it asserts.

 

In other key recommendations, the IOM report says:

  • The Department of Health and Human Services (HHS) should launch a national effort to develop a prioritization plan for antiviral treatment and prophylaxis in a pandemic, similar to the existing program for pandemic flu vaccine allocation. The plan should be designed to be adjusted as needed during a pandemic.
  • Healthcare and emergency workers who are in short supply and face repeated exposure to flu should be first in line for preventive antiviral treatment in a pandemic, followed by other healthcare and emergency workers and then by household contacts of flu patients.
  • The government should set up a federal advisory panel, similar to the Advisory Committee on Immunization Practices, to provide advice on public health and medical responses to a pandemic, including antiviral use.
  • The Shelf-Life Extension Program (SLEP) for antivirals in the federal stockpile—which extends the official shelf life for oseltamivir (Tamiflu) by 2 years—should be expanded to include state and private-sector antiviral stockpiles.
  • The government should consider using recently expired drugs that are in supplies outside the SLEP if a pandemic causes a shortage.

The 109-page report, titled Antivirals for Pandemic Influenza; Guidance on Developing a Distribution and Dispensing Program, was prepared by an eight-member committee chaired by June M. Osborn, MD, president emerita of the Josiah Macy, Jr. Foundation.

 

(Cont.)

 

The entire IOM report can either be ordered in paperback format, or read online, HERE.

 

Long time readers of this blog know I've tackled the Tamiflu question on several occasions, and I've questioned the size of our stockpile.

 

The idea that roughly 80 million 10-pill courses would suffice in a pandemic is based on two early assumptions, both of which are now called into question.

 

 

  • The attack rate of a pandemic would be roughly 25%
  • The 10-pill regimen of Tamiflu over 5 days is sufficient for H5N1

 

 

I suspect these original estimates were based more on what officials thought they could `sell' to their respective governments, more than on logic and science.  Budgets are tight, and spending money to thwart a pandemic that might not happen anytime soon is politically risky.

 

Two years ago, the 10-pill course for 25% of the population may have been seen as about as much as pandemic planners could hope for.  Better to get that, than ask for 3 times that much, and get turned down flat.

 

But we now know that the 10 pill course of Tamiflu is probably insufficient.   And estimates of the attack rate, the percentage of people who are sickened in a pandemic, have escalated over the past couple of years, going from a conservative 25% to speculation that 50% or more of the population may be susceptible.

 

Right now patients are routinely given more than the 2 pills a day for 5 days (10 pill course) of Tamiflu, and still, many of them die.  There are trials underway looking at whether a `double the dose for double the duration' will improve survival.  

 

In other words, instead of 10 pills, a course would require 40 pills.

 

 

The United States, which hopes to have enough Tamiflu on hand to treat about 24% of the nation (at the lower dose), would be down to only enough for 6.25% at the higher dose.

 

Of course, we don't know if the higher doses will improve patient outcomes.  Early data suggests that it might, but no controlled studies have been completed.

 


While we may find ways to extend our Tamiflu supply (Probenecid being one option), it is likely we will need at least twice as much Tamiflu as we have stockpiled in a severe pandemic.

 

 

Even at the heavily discounted price governments pay for Tamiflu, this is hardly chump change.   We are talking billions of dollars to purchase, and it has a limited shelf life.   Storage and distribution costs add to the bill.

 

 

One solution is to make Tamiflu easier for Americans to purchase.  Right now you need a doctor's prescription, and the cost is very high.  About $10 a pill.   Reduce the price and eliminate the need for a prescription, and you solve a large part of your stockpiling problem. 

 

Millions of American families would probably buy enough tamiflu for themselves if the price were reasonable, and the government was recommending it.  That would move the burden of buying much of the tamiflu from the government to individuals, and it would also mean that the medicine would be in the hands of the public when a pandemic began.

 

Worries that the public isn't responsible enough to keep some Tamiflu in their sock drawer for a rainy day are misplaced.   PSA's urging people not to use it unless a pandemic has erupted could be run on radio and TV stations, and would likely be very effective. 

 

People aren't as dumb as their governments like to believe.

 

 

 

 

There is a risk that once it is put into play combating a pandemic, overuse could drive the virus to become resistant, rendering the remainder of the stockpile pretty much useless.   And there are legitimate concerns about side effects, particularly among teenagers and children.  

 

And finally, Tamiflu is not approved for children under the age of one.

 

So Tamiflu isn't a panacea.  

 

But right now, we don't have a lot of options.  We either fight using the tools we have, or we accept whatever a pandemic throws at us.

Emmy Fitri On Indonesia's Pandemic Exercise

 

# 1921

 

 

Emmy Fitri, a reporter for the Jakarta Post, gives us a background piece explaining why scientists and doctors are concerned about another pandemic, and why their readers should be concerned as well.

 

 

 

Sunday, April 27, 2008  1:46 PM

 

Why bird flu? Why a pandemic simulation?

Emmy Fitri ,  The Jakarta Post ,  Jembrana, Bali   |  Sun, 04/27/2008 12:48 PM  |  Current Issues

 

CHECKING CHICKENS: A health official examines residents' chickens in Dangin Tukadaya village in Bali after a bird flu pandemic was declared in the area during a simulation on Friday. (JP/R.Berto Wedhatama)

 

CHECKING CHICKENS: A health official examines residents' chickens in Dangin Tukadaya village in Bali after a bird flu pandemic was declared in the area during a simulation on Friday. (JP/R.Berto Wedhatama)

 

 

When SARS struck several countries in 2003, the world was in shock. It was not prepared for the airborne infectious disease that moved like wildfire.

 

In the aftermath of the SARS outbreak, history repeated over and over and there were many could-haves and should-haves in dealing with it.

 

Ugly pandemics are part of our history. Years ago, in a less globalized world, the 1918 influenza pandemic and 1968 Hong Kong flu were precursors to the avian flu. They can teach us a lot about how to handle a pandemic.

 

It seems the world doesn't want to take any more chances. A disease outbreak could trigger a more horrid pandemic with a mere lack of preparation contributing to the death of millions.

 

When the avian influenza, originally a poultry disease, first emerged in Hong Kong in 1997, many scientists feared the H5N1 virus causing the flu could potentially become a pandemic transmitted between humans.

 

However, others have contradicted this theory, saying the fear is all hype.

 

Amid ongoing debate, Indonesia, the hardest hit country by the spread of avian influenza, has stepped up measures in anticipation of a pandemic.

 

"We didn't have proper warning systems in place for Indonesia's past natural disasters, including floods and earthquakes," said I Nyoman Kandun, the Health Ministry's director general of communicable disease and environment health.

 

"We'd like to be prepared for an avian influenza pandemic should it occur here," he said.

(Cont.)

Indonesia Wraps Up Pandemic Drill

 

# 1920

 

The three-day pandemic exercise being held this weekend on the island of Bali wraps up today with this drill held at the island's International Airport.

 

A Hat tip to Carol@SC on the Wiki for this report from Economic Times.

 

 

 

 

Indonesia runs airport bird flu drill

 

27 Apr, 2008, 1308 hrs IST, AGENCIES

JAKARTA: Indonesian authorities on Sunday wrapped up a major three-day bird flu drill on the resort island of Bali with an exercise focused on passengers at the island's international airport.

 


In the simulation, departing passengers were made to pass a scanner that detects body temperature. Among the travellers were three undercover personnel who simulated having high fever but insisted on leaving on their flights.

 

Staff steered them to a clinic at the airport and when test results showed they might have bird flu infections, the three were sent to the main hospital in Denpasar.

 

Despite posters notifying the public of the exercise, some tourists appeared concerned by the operations, as all personnel involved in the operation were wearing face masks.

 

"We were a bit worried but then we saw the posters. It's fine, better be prepared," said Angela Foster, an Australian tourist who was to fly back home through the airport.

 

"It is important as part of our bird flu containment efforts. We do not want to export a disease," I Nyoman Kandun, the health ministry's director general for handling of infectious disease, told journalists at the airport.

 

The simulation was the last part of a national exercise practising how to contain the spread of a bird flu outbreak.

Saturday, April 26, 2008

The HCW Debate Continues

# 1918




As a former paramedic one of the subjects I've focused on in this blog is the dilemma health care workers will face during a pandemic.


I understand the angst involved, for in the fall of 1976 when the world awaited the arrival of swine flu, just about everyone I knew (my world consisting primarily of medics, nurses, firefighters, cops, and doctors) was facing the same question:


Do I work in a pandemic, and not only risk my life, but risk bringing the virus home to my family?


It isn't an easy decision. In fact, it may be the hardest decision HCWs (Health Care Workers) will ever have to make.


For the past 6 months, Allnurses.com, an online community of more than 240,000 health care professionals, has been debating this issue in a thread called Will You Work In A Pandemic?


The assumption is a severe pandemic. One worse than 1918, with a high case fatality ratio.


A key concern of most HCW's is the predicted shortage of PPE's (Personal Protective Equipment: masks, gowns, gloves) during a pandemic. Few hospitals are stockpiling anywhere near enough to see them through a pandemic wave (estimated to last 8-12 weeks).


Officials who assume that nurses and other Health Care Workers (HCW's) will blindly risk themselves, and their families, by working without protective gear should read this thread.

It is an eye-opener.


A couple of days ago, the administrator at Allnurses added a poll to the thread, and as of this writing, there have been 325 responses. The results closely mirror other polls and studies conducted over the past couple of years.


50% said they would work in a pandemic, while 28% said they would not, and 21% said they weren't sure.






(click to enlarge)




The working assumption (sorry about the pun) of most pandemic planners is that absenteeism may run as high as 40%-50% during the height of a pandemic wave. They base this on the number of workers who may be ill, or may be home caring for a loved one.


For health care workers, those numbers will likely run much higher.


Health care workers, due to their direct contract with infected patients, are far more likely to contract the virus than the average worker. The rate of attrition due to illness is therefore likely to be higher than the national average.


Convalescence from pandemic influenza, as we saw in 1918, and as we are seeing with the H5N1 virus, often takes much longer than from seasonal flu. Even if a patient survives, it can involve a grueling recovery over a period of weeks, and sometimes with lasting sequelae.


Starting with a deficit of 30% or more, and then adding the losses due to illness and home care, hospitals could see their absentee levels running 70% or more at a time when patient loads will be astronomical.


Deteriorating working conditions, employee fatigue, and a lack of medicines and supplies could further impact hospital operations.


There are also concerns about possible violence directed at health care workers by families of patients who are turned away, or are denied life-saving procedures due to their triage status.


If you think that's an exaggeration, a couple of weeks ago Lt. Joseph McClellan of the Alabama Department of Homeland Security said:


"Security will need to be provided for mass burial sites, hospitals and pharmacies as fear and chaos could take hold of the community."


And the the assistant administrator for University of South Alabama Medical Center, said in the event of the pandemic barricades will go up at the facility's entrances to keep people who don't need to be there from entering the hospital and exposing themselves to germs.


Hospitals will rapidly become become one of the most stressful, and dangerous work environments during a pandemic.


Unknown also is how many support personnel, on which hospitals rely heavily, will opt not to work. Housekeeping, food service, maintenance, and clerical workers may also elect not to risk exposure.


Without masks (good ones, not surgical masks), gloves, and gowns, health care workers in direct contact with infected patients will likely contract the virus at an accelerated rate. Many would be sickened, and some might die, for lack of proper protective gear.


It would be hard to fault anyone for not being willing to work without the proper safety equipment.

We don't expect fire-fighters to run into a burning building without their bunker gear, how can we expect a nurse or other health care worker to treat infectious patients (with a potentially fatal disease) without masks and gloves?



While the United States has reportedly stockpiled 150 million masks in the Strategic National Stockpile, and hospitals, doctor's offices, and ambulance services undoubtedly have some reserves on hand, during a pandemic these disposable supplies will be consumed at an incredible rate.


Many hospitals have been reluctant to order in large quantities of PPE's due to the uncertainty of the pandemic threat, the costs involved, and the logistics of storage. Few facilities could operate without weekly deliveries of fresh supplies.


With roughly 8 million HCW's, assuming they were all working (which they won't), you'd need 25 million masks per day, and probably 50 million pairs of gloves.


Suddenly that 150 million mask stockpile doesn't look so impressive. It might last a couple of weeks.


The private stockpiles held by hospitals would extend this timetable, but they too would quickly run out. In a matter of weeks, during a severe pandemic, our current supplies would be extinguished.


What then?


A pandemic wave is expected to last for 6 to 12 weeks, and multiple waves are anticipated during a pandemic. Even when the number of cases in a community have died down, hospitals will likely be treating some patients.


There will be little rest for the weary HCW.


If 1918 was any indication, HCW's could be dealing with 200 `pandemic days' over an 18 month period. That's going to take a lot of PPE's. And the ability to restock in between waves, when everyone in the world will be clamoring for supplies, is doubtful.


You can add to these PPE's all of the other disposables that hospitals use routinely. IV's, Infusion kits, syringes, medicines of all sorts . . . even oxygen . . . these may all be in short supply during a pandemic.


We have 2 choices.


We either pay now to protect our healthcare workers by laying in the needed supplies, or we accept that somewhere down the line in a pandemic we will pay a much steeper price.


And no, this isn't just about influenza patients. While a pandemic rages, heart attacks, strokes, c-sections, car accidents, and every other medical need we see today will continue. More than 275,000 people rely on dialysis treatments. Who will care for them during a pandemic? What about those on chemotherapy? Or receiving radiation treatments?


There are nearly 1 million people in hospital beds in the United States on any given day, and 2 million more in long-term nursing facilities. Who will care for them?


Any way you slice it, health care workers are going to be one of our most precious assets during a pandemic. Having them on the job will mean the difference between life and death for millions of people.


They deserve to be protected.

Friday, April 25, 2008

The Myth Of JIT Prepping

 

# 1917

 

 

Two and a half years ago the United States government issued a recommendation that all families should store and maintain a two-week supply of food, water, and essential supplies.    Prior to that, FEMA and other emergency response agencies had suggested a 72-hour supply.

 

This change was brought about because of growing fears of a pandemic, and the experience of Hurricane Katrina, which showed it can take more than 72-hours for aid to arrive in a major disaster.

 

While the government is only urging a 2-week supply, because they believe it will suffice in most emergencies and is an obtainable goal for many (but not all) Americans, they wouldn't mind if you had more.

 

Numerous local governments, and health departments, around the country have recommended having anywhere from 2 weeks to 12 weeks of supplies on hand. 

 

A recent Australian study recommended every family have a `food lifeboat' with 90 days supplies on hand.

 

And you'll find that many flu bloggers, and most flu forums, have latched onto the 90-day-minimum stockpile to see your family through a pandemic.

 

I've advocated a 60 to 90 day supply since this blog began in January of 2006.  I've also stressed that these supplies need to be acquired in advance of a crisis, because once it becomes obvious that a crisis is upon us, the grocery store shelves will empty quickly.

 

Many people, however, still believe that JIT (Just In Time) prepping is still possible.  

 

This week, I believe that myth has been busted.

 

Over the past few weeks a relatively small handful of individuals and restaurant owners have stockpiled extra rice as a hedge against its rapidly escalating prices, and that has caused some large retail outlets to run short.   Buyers at Sam's and Costco, two major bulk distributors, have found either empty rice shelves or rationing at many locations.

 

While rice is currently the focus of these `runs on the store', other staples are reportedly in short supply as well.  Walmart, owner of Sam's Warehouse, says they have no plans `at this time'  to limit purchases of flour or cooking oil.  

 

That almost sounds comforting.

 

 

Imagine what it would have been like if, instead of a few hundred people stocking up, it had been millions of families all racing to the store to buy a 90-day supply of food?  

 

  

The days of stores having a `stock room' filled with pallets of food waiting to be put out on the floor are gone.   Stores use JIT stocking, and many get replenished every day of the week.  They know with amazing precision how many loaves of bread or cans of soup they will need until the next restocking.

 

At least in normal times.

 

Should a crisis, like a pandemic, suddenly rear its head the JIT model will crash.   In a matter of hours the store shelves will be wiped clean.

 

We see this phenomenon here in Florida whenever a hurricane approaches, and in northern climes, often with the approach of a blizzard.   Of course these are regional problems, and resources can usually be diverted from unaffected areas.  

 

A pandemic, however, is a global crisis.  And resources are going to be strained world wide.

 

Those who are not prepared in advance of a pandemic are going to find stockpiling difficult or impossible at the last minute.  

 

 

Even the Wall Street Journal's Opinion page is suggesting that stocking up is a good idea for Americans.   With the specter of continued inflation of prices, stockpiling makes financial sense.

 

 

R.O.I.

By BRETT ARENDS
 

Load Up the Pantry

April 21, 2008 6:47 p.m.

 

I don't want to alarm anybody, but maybe it's time for Americans to start stockpiling food.

 

No, this is not a drill.

 

You've seen the TV footage of food riots in parts of the developing world. Yes, they're a long way away from the U.S. But most foodstuffs operate in a global market. When the cost of wheat soars in Asia, it will do the same here.

 

Reality: Food prices are already rising here much faster than the returns you are likely to get from keeping your money in a bank or money-market fund. And there are very good reasons to believe prices on the shelves are about to start rising a lot faster.

(Cont.)

 

This is not a crisis that is likely to go away anytime soon.   There are many factors at work that are driving up food prices and reducing inventories. 

 

Here are just a few.

 

 

  • Some nations have resorted to ceasing exports of rice, to ensure they have enough for their own population.  
  • Australia, devastated by drought, has seen two major wheat harvest failures over the past two years. 
  • In Africa a  disease of wheat, Ug 99, or Ugandan Wheat Rust, now threatens that continent with huge losses in grain production.
  • One third of our corn crop is now being diverted into the production of biofuels like ethanol.
  • A greater demand for meat (which requires grain to raise) in developing countries.

 

 

Whether you do it for financial reasons, or as preparation against a future disaster, having a stockpile of food, water, and essential items simply makes sense.

 

The flu forums are excellent resources for information on what to stockpile, and in what quantity.  You'll also find good advice on how to rotate stock, tips on emergency cooking, and even recipes.  

 

The links are on the sidebar of my blog.

 

The Australian Food Lifeboat, also available on my sidebar, gives a recommended 90-day supply checklist.    

 

And pandemicflu.gov has this recommendation for all Americans.

 

Stock a supply of water and food. During a pandemic you may not be able to get to a store. Even if you can get to a store, it may be out of supplies. Public waterworks services may also be interrupted. Stocking supplies can be useful in other types of emergencies, such as power outages and disasters. Store foods that:

  • are nonperishable (will keep for a long time) and don't require refrigeration
  • are easy to prepare in case you are unable to cook
  • require little or no water, so you can conserve water for drinking

See a checklist of items to have on hand for an extended stay at home.

 

 

The idea that one day you could run to the store and find the shelves bare is a foreign one to most Americans.  But if we have a crisis, such as a pandemic, it could well happen.   The escalating food crisis around the world can only make matters worse.

 

If you haven't created an `emergency pantry', now is the time to do so.  Don't expect to complete this essential prep in one weekend.  It will likely take several weeks, and some serious thought and planning.

 

The Federal government hopes you'll stockpile 2-weeks worth of food, water, and essential supplies.  

 

I hope you'll do that, and more.

NAMRU-2 Debate Turns Ugly

 

# 1916

 

 

 

NAMRU-2 is our Naval Medical Research Unit #2, stationed in Jakarta  and specialists in tropical diseases.  Their  MoU, a Memorandum of Understanding, or contract with Indonesia expired on December 31st, 2005.

 

US diplomats have been trying to draft a new MoU, acceptable to both sides, for NAMRU-2 to operate under.    One of the key points the United States wants is diplomatic immunity for all NAMRU personnel.  Indonesia considers this unacceptable.

 

Some Indonesian  politicians appear anxious to take advantage of this impasse, as demonstrated by some of the charges levied below.

 

Not only are they claiming that NAMRU-2 has been of no benefit to Indonesia over the past 38 years, they are demanding an investigation into possible espionage on the part of the NAMRU personnel. 

 

Frankly, if the Indonesians want the U.S. to back down on their demand for diplomatic immunity, making reckless and unsubstantiated charges of espionage isn't the way to go about it. 

 

That's precisely the reason that nations grant and  use diplomatic immunity, to prevent their citizens from being detained on trumped up charges.

 

 

 

A Hat tip to Crof on Crofsblog for this article.    Crof has a few choice words on the subject as well,  first on the issue of diplomatic immunity, and then on these latest  inflammatory charges.

 

 

 

News Focus: Extension of RI-US cooperation on Namru-2 facing resistence


By Andi Abdussalam
Jakarta (ANTARA News) - The extension of operation with US Naval Medical Research Unit 2 (Namru2) now under negotiations between Indonesia and the United States is facing resistance from legislators and professionals.

 


"The government should stop and take over the operation of Namru-2 laboratory," Mutammimul Ula, member of the House of Representatives` Commission I which deals with foreign affairs, said here on Thursday.

 

During 30 years of operation in Indonesia, Namru-2 failed to provide the country with concrete benefits in the defense and health fields.
Mutammimul Ula claimed that other legislators agreed if the drafting process of a Memorandum of Understanding (MoU) released by the Foreign Ministry is terminated.

 

"Indonesia has now established cooperation with various institutions like the World Health Organization (WHO) to carry out researches and data transfers," he said adding that therefore the extension of cooperation with Namru-2 was not necessary.

 

"The government should adversely carry out investigation on allegation that the Namru-2 staffers were involved in intelligence operations," he said.

 

The US embassy in Jakarta should provide evidence and fact that Namru-2 is not an institution carrying out espionage activities, according to the legislator.

 

(Cont.)

Indonesia's Bird Flu Exercise Begins

 

# 1915

 

 

Indonesia's much publicized bird flu exercise began on Friday with hundreds of health workers and volunteers taking part. 

 

Conducted against a backdrop of increasingly strained relations with the United States and the World Health Organization (WHO), this exercise is designed to show that the Indonesian government is taking the bird flu threat seriously.

 

Perhaps. 

 

But in the three years since human cases began appearing in that country, the Indonesian government's response has been lackluster.  Grand schemes are proposed, but usually stall and sputter, through lack of local support. 

 

Here is how Antara News covered the first day of the exercise.

 

 

 

 

 

 

 

 

 

Indonesia runs massive bird flu drill

 


Tukad Daya, Bali (ANTARA News) - Hundreds of Indonesian villagers and health workers took part in a massive drill here Friday to prepare for a potentially devastating outbreak of human-to-human bird flu.

 


The largest bird flu drill ever held in Indonesia, the country worst hit by the virus, involved the simulated outbreak of a pandemic which experts say could rapidly spread across the globe killing millions of people.

 

"This is the biggest drill in Indonesia. The objective is to test the preparedness of bird flu officials to manage an outbreak in case it happens," health ministry disease control chief I Nyoman Kandun told reporters.

 

The three-day drill began at Tukaddaya village outside Jembrana, 80 kilometres (48 miles) west of Denpasar on the resort island of Bali, with a man presenting himself to a clinic with the symptoms of deadly avian influenza.

 

Health workers initially think he has been in contact with infected chickens -- until now the main way the virus has been caught by humans -- but the man explains that he has not been handling birds at all.

 

The virus is traced to another man in the village and health workers have to confront their worst fear -- the first outbreak of bird flu being transmitted from human to human.

 

The village is sealed off, birds and ducks are slaughtered and officials scramble to find and isolate other victims as they present themselves.
Villager I Wayan Nerken, 51, whose role in the drill was to report the sudden "death" of one of his chickens, said the exercise was "very useful."

 

"So far the information that we've got about bird flu has been limited to what we've seen on television. We don't really understand (how to act) when an infection happens," he told AFP.

 

"Before this I didn't know that we're not supposed to handle the carcasses when chickens die suddenly."

 

Some real residents of Tukaddaya fled as the simulation began, not out of concern for bird flu but just at the sight of all the officials, journalists and foreign observers descending on their quiet village.

 

More than 50 foreigners including 14 diplomats are taking part in the exercise, which is being covered by more than 50 local and international journalists.

Korean Corporal Recovering

 

# 1914

 

Presumably, at some point, we'll hear exactly what caused Corporal Cho's illness.   We've heard that it was bird flu,  then bacterial pneumonia, then a `less deadly variant of  bird flu',  and now that he possibly had a `common flu'.

 

In any event, the good news is, he has been pronounced `fully cured', although he remains hospitalized until definitive tests can be run.  

 

This from the Yonhap News Agency.

 

 

 

 

 

 

 

 

Soldier affected by bird flu recovers: health authorities


혻 혻 SEOUL, April 25 (Yonhap) -- A South Korean soldier who may have been infected with the bird flu virus has been declared "fully cured" by doctors, health authorities said Friday.

 


The soldier, who has been placed under quarantine since Sunday, has responded well to antibiotics and antiviral drugs, with his white cell count back to normal, the Korea Center for Disease Control and Prevention (KCDC) said.

 

It said the soldier's fever, sore throat and other symptoms that could be linked to bird flu have vanished, but added the patient will remain in the hospital for the time being until more detailed test results come in.

 

KCDC said earlier in the week that while the solider took part in the culling and burying of birds and initial tests showed he had been exposed to the avian influenza, his ill health may have been brought on by common flu.

 

Doctors said that he had been feeling ill before being assigned to the bird culling detail.

 

A handful of South Koreans tested positive for bird flu antibodies in their blood in the past although none have actually become sick. Antibodies in the blood is a telltale sign that a person was infected with a certain virus even if he or she did not get sick.

Thursday, April 24, 2008

Indonesia Responds To US Criticism

 

# 1913

 

The war of words between Indonesia and the United States continues with Indonesia now denying they want money for their bird flu virus samples. 

 

What they want, they claim, is " a mechanism that will ensure future pandemic vaccines are accessible to developing nations."

 

By `accessible', I assume they mean either cheap or free, and of course, in sufficient quantity.   

 

Their concern is understandable.  An unmitigated pandemic could do horrendous damage to any nation.  It is literally a national security issue.  And developing countries generally have a much younger population, that are likely to be more susceptible to a pandemic flu.

 

Unfortunately what they are demanding is a share of a commodity that doesn't yet exist.  

 

While there are great hopes of vaccine breakthroughs - such as cell-based technology -  that will allow us to create cheap and abundant pandemic vaccine in the future, we aren't there yet.    

 

Our current global manufacturing capacity would allow us to create about 750 million 2-shot vaccine courses in a year, assuming the adjuvants being tested are proved to be safe and effective. 

 

Or, enough for just over 10% of the world's population.  And that, remember, would take a year to produce.   No matter how you slice it, until these new technologies come online, 9 out of 10 people won't see a vaccine during the first year of a pandemic.

 

If a pandemic holds off for another two or three years, the picture hopefully changes, but there are still major logistical problems in delivering a vaccine to billions of people. 

 

In the meantime, the diplomatic game of thrust and parry continues, with no resolution in sight.

This from the Associated Press.

 

 

 

 

Indonesia defends its bird flu stance against US criticism

 

By ROBIN McDOWELL, Associated Press Writer Thu Apr 24, 4:05 AM ET

 

JAKARTA, Indonesia - Indonesia does not want money for its samples of a deadly bird flu virus, a health official said Wednesday after the U.S. criticized his country for refusing to share the samples with the international community.

 

Instead, Indonesia wants governments and pharmaceutical companies to come up with a mechanism that will ensure future pandemic vaccines are accessible to developing nations, said Widjaja Lukito, an adviser to Health Minister Siti Fadilah Supari.

 

 

That could include creating a multilateral trust that would enable price tiering or bulk purchasing of lifesaving vaccines, Lukito said.

 

 

The adviser was responding to comments made by Health and Human Services Secretary Mike Leavitt, who accused Indonesia of withholding virus samples from the World Health Organization since early 2007 because it wanted royalties or other monetary benefits.

 

 

"This is not a line we want to cross," Leavitt told The Associated Press at the end of a quick stopover in Indonesia last week. "Because it means the next unique virus we come across, wherever it is, we'll end up with people who say there is a price to pay for the virus."

 

 

He repeated the allegation on his blog, saying Supari's bottom line appeared to be "share samples, get paid."

 

(Cont.)

India Playing The Blame Game

 

# 1912

 

 

Going back to January, when bird flu first broke out in West Bengal, the Indian government has blamed Bangladesh.  So it is hardly surprising that the blame for the recent outbreak in Tripura is being laid at the Bangladeshi's doorstep.

 

Although the Indian government has made some outlandish claims (see The Virus My Friend, Is Blowin In The Wind) in this regard, there is a pretty good chance that their bird flu woes came by way of Bangladesh, which has been fighting a losing battle against the disease for more than a  year.

 

The West Bengal government, however, ignored early reports of bird deaths back in December, and failed to act swiftly enough to contain the virus.  The virus reportedly spread, virtually unhindered, for nearly a month.  And once action was taken, it was often poorly organized and only partially effective

 

The H5N1 bird flu virus may well have come into India by way of Bangladesh (unproven, but certainly possible), but it became entrenched due to the slow and often ineffective actions by the local government.

 

But, when local economies are affected, and lives are negatively impacted, it is only good politics to shift the blame to a neighboring country.

 

 

 

 

India blames Bangladesh as bird flu spreads

By Biswajyoti Das 17 minutes ago

GUWAHATI, India (Reuters) - Authorities battling an outbreak of bird flu in poultry in Tripura blamed Bangladesh for the spread on Thursday, but many experts said India was not doing enough to contain the virus.


More than 25,000 chickens and ducks have already been slaughtered in Tripura this month after it was hit by the H5N1 strain.

 

On Thursday, authorities chose to blame neighbouring Bangladesh after they received reports of new bird flu cases in the state.

 

"Unless bird flu is contained completely in Bangladesh, the virus will keep spreading in Tripura," U. Venkatateswarlu, a top official of the animal resource development department said.

 

The remote northeastern state borders Bangladesh, where more than half the country's districts have been affected by the virus.

 

"Our main problem in controlling the situation is because of close proximity with Bangladesh," Venkatateswarlu added.

 

But many people disagreed.

 

For the past two days, while hundreds of birds mysteriously died in remote villages, complaints from people were largely ignored by state authorities, some officials and animal experts said.

 

"It is foolish on their part to blame Bangladesh for their own doing," N.G. Jayasimha of the People for the Ethical Treatment of Animals (PETA), an animal rights group, told Reuters from Mumbai.

 

"We had warned the Tripura government about bird flu and we told them the reason for the spread of bird flu is because of bad farm practices," he said by telephone.

 

"They sat on our report and did nothing."

(Cont. )