Thursday, November 17, 2011

Get Smart About Antibiotics Week




# 5966



Short of seeing a Category 5 pandemic, I can think of no health threat that has a greater potential to threaten the general public than does the global rise in antibiotic resistant bacteria.


As Maryn McKenna so eloquently explained in her book Superbug: The Fatal Menace Of MRSA, not only are many of our older antibiotics losing their effectiveness, the number of replacement antibiotics under development is distressingly limited.


While it may sound alarmist, there are many scientists who fear that one day we may find ourselves facing a post-antibiotic world, where many of the infections we can treat today will no longer respond to the antibiotics we have remaining.


In April of this year, Margaret Chan – Director General of the World Health Organizationin a speech for World Health Day 2011, issued this stark warning:


In the absence of urgent corrective and protective actions, the world is heading towards a post-antibiotic era, in which many common infections will no longer have a cure and, once again, kill unabated.



Since much of this resistance has come about from inappropriate use of antibiotics (in humans, and on the farm), the immediate focus is on ways to curb their improper use.


This week the CDC is promoting their GET SMART about antibiotics campaign, while countries across Europe are promoting European Antibiotic Awareness Day tomorrow, November 18th.




Today, a round up of some antibiotic resistance resources for you to explore.



First stop, a short video from the CDC on the appropriate use of antibiotics.



The CDC has also introduced a number of new fact sheets and other promotional material for 2011 on antibiotic resistance.


Fact Sheets New 2011



Across the pond, the ECDC has posted a short (8 minute) documentary on antibiotic resistance, and some short PSA announcements which can be viewed at this link.



You’ll find additional European initiatives and information on the European Antibiotics Awareness Day website.


In support of the CDC & ECDC awareness campaigns, Clinical Infectious Diseases  and The Journal of Infectious Diseases  have made a number of recent articles on antibiotic resistance freely available for the month of November.


Clinical Infectious Diseases articles:

Editorial commentary: Outpatient Antibiotic Use in the United States: Time to "Get Smarter"

Behavior Change Strategies to Influence Antimicrobial Prescribing in Acute Care: A Systematic Review

The Interface Between Antibiotic Resistance and Virulence in Staphylococcus aureusand Its Impact Upon Clinical Outcomes

Rapid Diagnostics and Appropriate Antibiotic Use

Strategies for Reduction in Duration of Antibiotic Use in Hospitalized Patients

The Journal of Infectious Diseases articles:

Editor's Choice: Antibiotic Choice May Not Explain Poorer Outcomes in Patients With Staphylococcus aureus Bacteremia and High Vancomycin Minimum Inhibitory Concentrations

Editorial commentary: At What Cost Echinocandin Resistance?

Acinetobacter baumannii Resistant to Colistin Alters Its Antibiotic Resistance Profile: A Case Report From Spain

The Combination of a Tumor Necrosis Factor Inhibitor and Antibiotic Alleviates Staphylococcal Arthritis and Sepsis in Mice

Divergent Mechanisms for Passive Pneumococcal Resistance to &szlig-Lactam Antibiotics in the Presence of Haemophilus influenza



And for good measure, a sampling of some of my antibiotic resistance essays from the past year.


India: The NDM-1 Story Continues
CDDEP: Mapping Resistance
NDM-1: One Year Later
ECDC/EMEA: Joint Report On Resistant Bacteria
Carbapenemases Rising

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