Tuesday, January 16, 2024

Hong Kong CHP Monitoring An H5N6 Case In Sichuan Province


#17,868

Hong Kong's CHP has published a bare-bones report on another H5N6 case on the Mainland, one which occurred nearly a month before they reported their last case on December 22nd (see Hong Kong CHP Monitoring Fatal H5N6 Infection On Mainland (Sichuan)), also from Sichuan province. 

Details, as usual, are scant; Age (59), Gender (F), and Location ( Ziyang City in Sichuan Province) along with the patient's condition (serious) as of November 29th. The patient reportedly had visited a live poultry market prior to falling ill. 

Belated reporting of cases has become the norm out of China, with delays of 6 to 10 weeks not uncommon. The announcement from HK's CHP follows, after which I'll have a bit more.

CHP closely monitors human case of avian influenza A(H5N6) on Mainland

The Centre for Health Protection (CHP) of the Department of Health is today (January 16) closely monitoring a human case of avian influenza A(H5N6) on the Mainland, and again urged the public to maintain strict personal, food and environmental hygiene both locally and during travel.

The case involves a 59-year-old female living in Ziyang City in Sichuan Province, who had visited a live poultry market before the onset of symptoms. She developed symptoms on November 25 last year and was admitted for treatment on November 29 with serious condition.

From 2014 to date, 89 human cases of avian influenza A(H5N6) have been reported by Mainland health authorities.

"All novel influenza A infections, including H5N6, are notifiable infectious diseases in Hong Kong," a spokesman for the CHP said.

Travellers to the Mainland or other affected areas must avoid visiting wet markets, live poultry markets or farms. They should be alert to the presence of backyard poultry when visiting relatives and friends. They should also avoid purchasing live or freshly slaughtered poultry, and avoid touching poultry/birds or their droppings. They should strictly observe personal and hand hygiene when visiting any place with live poultry.

Travellers returning from affected areas should consult a doctor promptly if symptoms develop, and inform the doctor of their travel history for prompt diagnosis and treatment of potential diseases. It is essential to tell the doctor if they have seen any live poultry during travel, which may imply possible exposure to contaminated environments. This will enable the doctor to assess the possibility of avian influenza and arrange necessary investigations and appropriate treatment in a timely manner.

While local surveillance, prevention and control measures are in place, the CHP will remain vigilant and work closely with the World Health Organization and relevant health authorities to monitor the latest developments.

The public should maintain strict personal, hand, food and environmental hygiene and take heed of the advice below when handling poultry:
  • Avoid touching poultry, birds, animals or their droppings;
  • When buying live chickens, do not touch them and their droppings. Do not blow at their bottoms. Wash eggs with detergent if soiled with faecal matter and cook and consume the eggs immediately. Always wash hands thoroughly with soap and water after handling chickens and eggs;
  • Eggs should be cooked well until the white and yolk become firm. Do not eat raw eggs or dip cooked food into any sauce with raw eggs. Poultry should be cooked thoroughly. If there is pinkish juice running from the cooked poultry or the middle part of its bone is still red, the poultry should be cooked again until fully done;
  • Wash hands frequently, especially before touching the mouth, nose or eyes, before handling food or eating, and after going to the toilet, touching public installations or equipment such as escalator handrails, elevator control panels or door knobs, or when hands are dirtied by respiratory secretions after coughing or sneezing; and
  • Wear a mask if fever or respiratory symptoms develop, when going to a hospital or clinic, or while taking care of patients with fever or respiratory symptoms.
​The public may visit the CHP's pages for more information: the avian influenza page, the weekly Avian Influenza Report, global statistics and affected areas of avian influenza, the Facebook Page and the YouTube Channel.

Ends/Tuesday, January 16, 2024
Issued at HKT 17:00

While China's H5+H7 poultry vaccination program quickly eradicated the H7N9 virus, it appears to have been less successful in controlling H5N6.  Nearly all human cases report recent contact with live poultry, yet we almost never hear of a symptomatic outbreak in domesticated birds. 

Recent studies (see mSphere: An HPAI H5N6 Virus With Remarkable Tropism for Extra-respiratory Organs in the Ferret Model) suggest the H5N6 virus continues to adapt to mammalian hosts, while 18 months ago the Lancet published Resurgence of H5N6 Avian Influenza Virus in 2021 Poses New Threat to Public Health.

H5N6 - along with Cambodia's clade 2.3.2.1c H5N1 virus - remind us that HPAI H5 continues to explore multiple evolutionary paths, and that we may see others emerge over time.