Monday, May 06, 2019

WHO Update & Risk Assessment: Measles In Europe

https://www.who.int/csr/don/06-may-2019-measles-euro/en/













#14,047


While the CDC reports that the United States has seen our greatest number of Measles cases since 1994 (n=704 cases as of April 26th, across 22 states) - that number pales in comparison with what is going on in Europe (see chart above).

Contrary to the evidence, too many people still believe that measles is a trivial childhood illness.  This from the WHO's Key Facts on Measles: 
Measles
29 November 2018
  • Even though a safe and cost-effective vaccine is available, in 2017, there were 110 000 measles deaths globally, mostly among children under the age of five.
  • Measles vaccination resulted in a 80% drop in measles deaths between 2000 and 2017 worldwide.
  • In 2017, about 85% of the world's children received one dose of measles vaccine by their first birthday through routine health services – up from 72% in 2000.
  • During 2000-2017, measles vaccination prevented an estimated 21.1 million deaths making measles vaccine one of the best buys in public health.


Today the World Health Organization has published the following 1st quarter summary of measles in the European Region, which finds nearly 85,000 cases and 79 deaths in the first 3 months of 2019. 

Measles – European Region
Disease outbreak news - update
6 May 2019

In the first two months of 2019, 34 300 measles cases have been reported in 42 countries of the WHO European Region, including 13 measles-related deaths in three countries (Albania, Romania and Ukraine). The majority of cases are reported in Ukraine, with more than 25 000 cases (>70%)1.

As of 28 March 2019, the WHO European Region reported a total of 83 540 measles cases and 74 related deaths. This is compared to 25 863 cases and 42 deaths in 2017, and 5 273 cases and 13 deaths in 2016. In 2018, eight countries reported over 2 000 cases each including Ukraine (n= 53 218), Serbia (n=5 076), France (n=2 913), Israel (3 140), Italy, (n=2 686), Russian Federation (n=2 256), Georgia (n=2 203) and Greece (n=2 193).

Although the European Region achieved its highest ever estimated coverage for the second dose of measles vaccination in 2017 (90%), countries with measles outbreaks have experienced a range of challenges in recent years including a decline or stagnation in overall routine immunization coverage in some cases, low coverage at subnational level or among some marginalized groups and immunity gaps in older populations. Most cases are occurring in unvaccinated or under-vaccinated individuals.

According to the most recent report from the European Regional Verification Commission for Measles and Rubella Elimination (RVC), based on 2017 data, measles elimination has been verified in 37 (out of the 53) countries in the WHO European Region, which documented interrupted transmission for at least 36 months. Five countries provided evidence for the interruption of measles transmission for a period of at least 24 months but less than 36 months, and one for interruption for transmission for 12 months. Ten countries including Belgium, Bosnia and Herzegovina, France, Georgia, Germany, Italy, Romania, Russian Federation, Serbia and Ukraine remain endemic for measles. The RVC will meet in June 2019 to review reports from National Verification Committees (NVCs) for measles and rubella elimination documenting each country’s status by the end of 2018. All countries reporting measles cases continuously for 12 months or more will have to provide a detailed epidemiological and molecular epidemiology (measles virus genotypes and lineages) analysis to document absence of continuous measles transmission or re-established endemic transmission.


WHO risk assessment

Measles is a highly contagious viral disease. It remains one of the leading causes of morbidity and mortality among young children globally, despite the availability of a safe and effective vaccine. Transmission from person-to-person is airborne, as well as by direct or indirect contact of secretions (nasal, throat) of an infected person. The virus can cause widespread outbreaks in the presence of large numbers of susceptible persons.

Even with implementation of outbreak response measures, measles continues to circulate in the European Region as a result of suboptimal vaccination coverage and population immunity gaps. If outbreak response is not timely and comprehensive, the virus will find its way into more pockets of vulnerable individuals and potentially spread to additional countries within and beyond the Region. It is proportional to the size of the population that remains susceptible to measles. Measles has also been reported among health workers and nosocomial transmission has contributed to some outbreaks.

The impact on public health will persist until the ongoing outbreaks are controlled, routine immunization coverage is continuously high (≥ 95%) and immunity gaps in the population closed. As long as measles continues to circulate anywhere in the world, no country can avoid importation, but they can protect their populations through high routine and supplemental immunization coverage of susceptible individuals.



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