Avian Flu Diary: COCA Call Tomorrow (Oct 6th): Situational Update for Clinicians About Severe Monkeypox Virus Infections

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A week ago, while this blog was offline due to Hurricane Ian, the CDC released a HAN Advisory (see below) detailing severe presentations of Monkeypox infection among immunocompromised individuals.

Health Alert Network (HAN) No. 475 – Severe Manifestations of Monkeypox among People who are Immunocompromised Due to HIV or Other Conditions 09/29/2022 2:15 PM

Tomorrow (Oct 6th) the CDC will hold a follow up COCA Call for clinicians (details below) where presenters from the CDC and various medical institutions will provide their experiences treating severe monkeypox infection, and review the latest treatment and prevention information.

These 1-hour presentations are usually technical in nature, and are of greatest interest to clinicians and healthcare providers, but also may be of interest to others.

If you are unable to attend the live presentation, these (and past) webinars are always archived and available for later viewing at this LINK.

Situational Update for Clinicians about Severe Monkeypox Virus Infections

Overview

This COCA Call supports and expands on the Centers for Disease Control (CDC) Health Alert Network (HAN) Health Advisory released on September 29, 2022, about people experiencing severe manifestations of monkeypox and medical countermeasures available to treat people who have monkeypox.

The HAN Health Advisory informs healthcare providers that Severe manifestations of monkeypox have been observed in the United States in the current outbreak.
People who are immunocompromised due to HIV or other conditions are at higher risk for severe manifestations of monkeypox than people who are immunocompetent.
Because people with HIV-associated immunocompromise are at risk for severe manifestations of monkeypox, the HIV status of all sexually active adults and adolescents with suspected or confirmed monkeypox should be determined.
There are diagnostic and clinical management strategies that may help address severe manifestations of monkeypox.

During this COCA Call, presenters from CDC, the Los Angeles County Department of Public Health, and Emory University will share an update about people with monkeypox who have severe manifestations of the disease. Presenters will also describe the clinical courses of two patients with monkeypox, review interventions to prevent and treat monkeypox with antiviral therapy, discuss updated information about the risk of monkeypox transmission, and provide new guidance on selecting a site on the body when administering the vaccine intradermally.

Presenters

Agam Rao, MD, FIDSA
CAPT, U.S. Public Health Service
Subject Matter Expert, Vaccine Task Force and Clinical Task Force
2022 Multinational Monkeypox Response
Centers for Disease Control and Prevention

Caroline Schrodt, MD, MSPH
LCDR, U.S. Public Health Service
Lead, Clinical Escalations Team
2022 Multinational Monkeypox Response
Centers for Disease Control and Prevention

Jemma Alarcón, MD, MPH
Los Angeles County Department of Public Health
Epidemic Intelligence Service Officer
2022 Multinational Monkeypox Response
Centers for Disease Control and Prevention