Tuesday, June 06, 2023

UKHSA: Gonorrhoea and Syphilis at Record Levels in 2022


Credit CDC PHIL

 #17,485

Although most STIs (sexually transmitted infections) are still treatable by modern antibiotics, 5 months ago in Massachusetts DPH: First Detection Of Gonorrhea Strain With Resistance To 5 Classes of Antibiotics we looked at growing concerns over antibiotic resistant gonorrhea in the United States. 

While both of the above cases were ultimately cured, we've seen warnings for years (see 2011's The Path Of Increased Resistance and Going, Going, Gonorrhea) that our armamentarium against this all-too-common sexually transmitted disease (STD) was eroding.

At the same time, the number of STDs continue to rise, both here in the United States and around the world. Today the UK's Health Security Agency has released their latest numbers for the year 2022, which finds a 50% increase in gonorrhea cases last year, making it the highest number since record keeping began in 1918. 

The number of syphilis infections was the highest since 1948. 

The HSA press release follows.  I'll have a postscript after the break.

Gonorrhoea and syphilis at record levels in 2022
Last year, gonorrhoea diagnoses were highest on record and syphilis diagnoses were highest since 1948.

From:UK Health Security Agency Published6 June 2023 Last updated6 June 2023 — See all updates




New data from the UK Health Security Agency (UKHSA) published today shows record levels of gonorrhoea and syphilis diagnoses in 2022.

The latest data shows:
  • gonorrhoea diagnoses increased to 82,592 in 2022, an increase of 50.3% compared to 2021 (54,961) and 16.1% compared to 2019 (prior to the COVID-19 pandemic) – this is the highest number of diagnoses in any one year since records began in 1918
  • infectious syphilis diagnoses increased to 8,692 in 2022, up 15.2% compared to 2021 (7,543) and 8.1% compared to 2019 – this is the largest annual number since 1948
  • people aged 15 to 24 years remain the most likely to be diagnosed with sexually transmitted infections (STIs)
  • in 2022, there were over 400 diagnoses of STIs made each day among young people

UKHSA is reminding everyone having sex with new or casual partners to wear a condom and get tested regularly, whatever their age or sexual orientation. Testing is free and confidential and you should get tested even if you are not showing any symptoms.

Though STIs are usually easily treated with antibiotics, many can cause serious health issues if left untreated. Chlamydia and gonorrhoea can cause infertility and pelvic inflammatory disease, while syphilis can cause serious, irreversible and potentially life-threatening problems with your brain, heart, or nerves.

Dr Hamish Mohammed, Consultant Epidemiologist at UKHSA, said:
We saw more gonorrhoea diagnoses in 2022 than ever before, with large rises particularly in young people. STIs aren’t just an inconvenience – they can have a major impact on your health and that of any sexual partners. Condoms are the best defence, but if you didn’t use one the last time you had sex with a new or casual partner, get tested to detect any potential infections early and prevent passing them on to others. Testing is important because you may not have any symptoms of an STI.
If you are having condomless sex with new or casual partners, regular testing for STIs and HIV is essential to maintain good sexual health. Testing is free and can be accessed through local sexual health clinics, university and college medical centres or through self-sampling kits sent discreetly through the post.

In 2022, there were 2,195,909 sexual health screens (diagnostic tests for chlamydia, gonorrhoea, syphilis or HIV) performed by sexual health services, an increase of 13.4% compared to 2021 (1,936,455).

While the increase in gonorrhoea and syphilis diagnoses will in part be due to increases in testing, the scale of the increase in diagnoses strongly suggests that there is more transmission of STIs within the population.

Gonorrhoea is becoming increasingly resistant to antibiotics and at risk of becoming untreatable in the future, making it vital that people test early and diagnose the infection so that they can prevent passing it on.

Regular screening for STIs and HIV, on at least an annual basis, is essential to maintain good sexual health for everyone having condomless sex with new or casual partners. In addition:
  • women, and other people with a womb and ovaries, aged under 25 years who are sexually active should have a chlamydia test after having sex with a new partner or annually
  • gay, bisexual and other men who have sex with men should have tests for HIV and STIs annually or every 3 months if having condomless sex with new or casual partners

Although the numbers are likely incomplete due to the impact of the COVID pandemic, the latest numbers from the CDC (up to 2021) indicate STDs continue to rise in the United States as well. 



More than 2.5 million cases of chlamydia, gonorrhea, and syphilis were reported in 2021

Sexually Transmitted Disease Surveillance, 2021 provides the most current and complete data for nationally notifiable sexually transmitted infections (STIs). In 2021, chlamydia, gonorrhea, and syphilis continued to increase in the United States. Disruptions in STI-related prevention and care services due to the COVID-19 pandemic likely continued in 2021, but the impact was most acute in 2020. While the pandemic exposed shortcomings within public health, the nation’s response offers lessons learned that could help reverse rising STI trends.
 
In 2009, the CDC recorded 301,174 cases of gonorrhea, while in 2021 that number was pegged at 710,151.  According to the CDC, reported cases of syphilis (all stages) have increased 74 percent since 2017, totaling more than 176,000 cases in 2021.

While antibiotics still work today for most infections, for tens of thousands of people every year, the oft-predicted `post-antibiotic era' is already here. According to a recent report from the CDC:

In the 2019 report, the last year comprehensive healthcare and community data were available to calculate, CDC estimated that more than 2.8 million antimicrobial-resistant infections occur in the U.S. each year, with more than 35,000 people dying as a result. 

While I cover AMR topics occasionally in this blog, I can heartily recommend CIDRAP's Antimicrobial Stewardship Project as the best place to learn about the growing global threat of AMR.

You'll also want to check out the CIDRAP-ASP Youtube Channel, which has more than 24 hours of lectures and webinars on Antimicrobial stewardship.