Showing posts with label Journal Nature. Show all posts
Showing posts with label Journal Nature. Show all posts

Tuesday, July 29, 2014

The Journal Nature Weighs In On Lab Accidents & Biosafety

image

 

 


# 8890

 

In the wake of revelations regarding laboratory safety lapses both at the FDA and the CDC involving `select agents’ including anthrax, smallpox, and H5N1 avian influenza, and the ongoing Debate Over Gain Of Function research, we are seeing agencies, scientific journals, universities, politicians, consultants, newspaper editorial boards, scientific working groups, and individual scientists all publicly staking out their positions on these issues.

 

A little over two weeks ago, the Cambridge Working Group produced a consensus statement, which urges caution, and better regulation and oversight of laboratory research seeking to enhance the virulence, transmissibility, or host range of pathogens with pandemic potential (PPPs).

 

While just yesterday, the newly formed coalition Scientists for Science, posted a statement of their own, that called their work `essential’ and dismissed many of the concerns being raised over GOF research as being overstated.

 

Not everyone is convinced, however, as evidenced by last week’s ECDC Comment On Gain Of Function Research, which acknowledged the potential public health risks that these types of experiments can pose, and proposed that the overriding concern of researchers should be first, and foremost  `to do no harm.’

 

Today the Journal Nature has two articles on Laboratory safety standards (or the lack thereof).  First an article by Declan Butler, on the lack of universal, and consistent standards for laboratories conducting work on potentially dangerous pathogens.

 

Biosafety controls come under fire

Experts call for a stronger safety culture at secure sites after incidents involving anthrax and flu in a US laboratory.

Declan Butler

29 July 2014

Recent accidents involving deadly pathogens at a leading laboratory in the United States highlight the need for a major global rethink of biosafety controls, experts say.

The Centers for Disease Control and Prevention (CDC) in Atlanta, Georgia, reported two accidents involving anthrax and the deadly H5N1 influenza virus. Biosafety professionals argue that such incidents show that without a strong culture of biosafety, even highly secure facilities are susceptible to errors that could place workers and the public at risk.

(Continue . . . )

 


A second report, this time an editorial, suggests that lab accidents such as the ones making headlines this summer happen far more often than are ever reported, and calls for full transparency.

 

Safety doesn’t happen by accident

To create a strong biosafety culture, information on mishaps involving deadly pathogens must be reported and shared fully and transparently.

(Continue . . .)

Thursday, October 03, 2013

Nature: Berkeley Professor Calls For A National Seismic Warning System

image

Seismic Hazard Map – Credit USGS 

 

 


# 7833

 

Japan has one, as does Mexico, China, and Romania.  An automated alert system that could provide invaluable seconds, or perhaps even a few minutes, warning of a major earthquake to some of the most seismically vulnerable areas of the United States. 

 

Enough time to slow or stop trains or monorails, enough time to alert children in schools to get outside or under their desks, even enough advance warning for hazardous chemical manufacturers or nuclear power plants to take steps to safe their operations.

 

Although California has been testing a small scale warning system – created and run by academic institutions - for the past two years, it is more of a proof of concept than a full-fledged system.  Recently a bill was passed by the California legislature to move forward with an expansion of the system (see AP article Bill would create California quake warning system), but does not address where the money will come from to run it.

 

Yesterday, Richard Allen - director of the Berkeley Seismological Laboratory and a professor in the Department of Earth and Planetary Science at the University of California, Berkeley – wrote an appeal in the Journal Nature for such a system to be funded – first in California, then across the nation – before the next big quake hits.

 

You an read his comment at the link below.

 

Seismic hazards: Seconds count

Richard Allen

02 October 2013

The United States should install an earthquake early-warning system now — and before the next big one hits, says Richard Allen.

The United States will be hit by a major earthquake causing hundreds of fatalities within my lifetime. Whether it will be in 20 years, 2 years, or tomorrow, we do not know. Such an event will prompt the country to implement a public earthquake early-warning system, giving people seconds or minutes to prepare for the shaking. Rather than waiting until the next big quake galvanizes political action, I believe that we must build an alert system now.

(Continue . . .)

 

 

And a reminder (see NPM13: A Whole Lotta Shakeouts Going On), two weeks from today, California – along with many other states and regions – will be holding their annual Shakeout Earthquake drill.

 

image

(click image to visit Shakeout.org)

 

Millions of residents, from the United States and Canada, to New Zealand, Italy, and Japan, will take part in this yearly Drop, Cover, & Hold On drill. A video, demonstrating the technique is available on the California Shakeout Youtube Channel.

 

If you live in any of these regions, I would encourage you to participate in, and support, these annual disaster drills.

Wednesday, April 24, 2013

Nature: H7N9 – A Virus Worth Worrying About

 

 


# 7184

 

 

The Journal Nature this morning has a commentary by Dr. Peter Horby - Director of the Oxford University Clinical Research Unit in Hanoi, Vietnam – who explains why he and some of his colleagues believe the threat of H7N9 should not be ignored.

 

 

H7N9 is a virus worth worrying about

Warnings about the emergence of another influenza virus may elicit scepticism, but we should not be complacent, cautions Peter Horby.

 


Highly recommended.

Wednesday, December 07, 2011

Nature: Special Influenza Supplement

 

 

 

# 5995

 

 

The journal Nature has released a special, freely accessible, influenza-centric supplement on their website today. 

 

 

You’ll find articles on antiviral drugs, vaccines, epidemiology, and viral evolution. While I’ve only just quickly scanned a couple of the articles, it looks very much worth perusing.

 

Follow the link below to read:

 

Influenza

image 

Vol. 480, No. 7376 (08 December 2011)

Produced with support from Sanofi Pasteur, Crucell and Baxter.

 

Our centuries-old battle against influenza occasionally erupts into mass death – the 1918 pandemic alone killed at least 50 million people. What makes this virus such a tough foe is its ability to mutate so that vaccines and drugs quickly become obsolete. Can new research offer hope for defeating this pathogen for good?

Wednesday, August 18, 2010

Nature Editorial: After The Pandemic

 

 

# 4819

 

 

The respected Journal Nature has published a brief editorial on the WHO’s (World Health Organization’s) handling of the pandemic.

 

 

After the pandemic

Date published: (19 August 2010)
DOI:10.1038/466903b

Despite some mistakes, the World Health Organization handled the flu outbreak well.

 

A hat tip to Ironorehopper on FluTrackers for posting this link.

 

In early June Nature published a detailed rebuttal of many of the outrageous conflict-of-interest allegations that have been cast in the WHO’s direction, so it isn’t terribly surprising to see this editorial stance.

 

(See Experts Weigh In On Allegations Against The WHO)

 

After months of the media reporting on unsubstantiated accusations of impropriety on the part of the WHO, I’m heartened to hear some reasonable and respected voices speaking out.

 

A few of my essays on this `blame game’ directed at the WHO, the CDC, and vaccine manufacturers includes:

 

WHO To Review Their Pandemic Response

Hubris And The Flu

Before We Ride Down And Shoot The Survivors.