Showing posts with label Cancer. Show all posts
Showing posts with label Cancer. Show all posts

Thursday, February 28, 2013

WHO: Estimated Health Risks From The Fukushima Radiation Release

 

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# 6973

 


The World Health Organization has today published a 172-page Health risk assessment from the nuclear accident after the 2011 Great East Japan earthquake and tsunami, based on a preliminary dose estimation  based on a preliminary estimate of radiation doses published in May 2012.

 

First some excerpts from the press release, then I’ll be back with a little more.

 

Global report on Fukushima nuclear accident details health risks

News release

28 February 2013 | GENEVA - A comprehensive assessment by international experts on the health risks associated with the Fukushima Daiichi nuclear power plant (NPP) disaster in Japan has concluded that, for the general population inside and outside of Japan, the predicted risks are low and no observable increases in cancer rates above baseline rates are anticipated.

 

The WHO report ‘Health Risk Assessment from the nuclear accident after the 2011 Great East Japan Earthquake and Tsunami based on preliminary dose estimation’ noted, however, that the estimated risk for specific cancers in certain subsets of the population in Fukushima Prefecture has increased and, as such, it calls for long term continued monitoring and health screening for those people.

 

Experts estimated risks in the general population in Fukushima Prefecture, the rest of Japan and the rest of the world, plus the power plant and emergency workers that may have been exposed during the emergency phase response.

 

“The primary concern identified in this report is related to specific cancer risks linked to particular locations and demographic factors,” says Dr Maria Neira, WHO Director for Public Health and Environment. “A breakdown of data, based on age, gender and proximity to the nuclear plant, does show a higher cancer risk for those located in the most contaminated parts. Outside these parts - even in locations inside Fukushima Prefecture - no observable increases in cancer incidence are expected.”

 

In terms of specific cancers, for people in the most contaminated location, the estimated increased risks over what would normally be expected are:

  • all solid cancers - around 4% in females exposed as infants;
  • breast cancer - around 6% in females exposed as infants;
  • leukaemia - around 7% in males exposed as infants;
  • thyroid cancer - up to 70% in females exposed as infants (the normally expected risk of thyroid cancer in females over lifetime is 0.75% and the additional lifetime risk assessed for females exposed as infants in the most affected location is 0.50%).

For people in the second most contaminated location of Fukushima Prefecture, the estimated risks are approximately one-half of those in the location with the highest doses.

 

The report also references a section to the special case of the emergency workers inside the Fukushima NPP. Around two-thirds of emergency workers are estimated to have cancer risks in line with the general population, while one-third is estimated to have an increased risk.

 

The almost-200-page document further notes that the radiation doses from the damaged nuclear power plant are not expected to cause an increase in the incidence of miscarriages, stillbirths and other physical and mental conditions that can affect babies born after the accident.

 

“The WHO report underlines the need for long-term health monitoring of those who are at high risk, along with the provision of necessary medical follow-up and support services,” says Dr Maria Neira, WHO Director for Public Health and Environment. “This will remain an important element in the public health response to the disaster for decades.”

(Continue . . . )

 

 

This press release deals primarily with the relative increases in risk among populations living or working very close to the Fukushima nuclear accident who received the highest exposure to radiation.

 

While relative risk is a valid way of looking at this accident’s impact - it is also helpful to look at the absolute risk (which is done in the FAQ and in the actual report) - particularly when looking at cancers that have a low baseline rate.

 

  • The largest increase in relative risk was for developing thyroid cancer among infant girls in their lifetime. The baseline rate in Japan is roughly .75% (1 in 133). Those living closest to the radiation leaks are expected to see a 70% increase, which elevates the absolute risk to approximately 1.25% (1 in 80).

 

  • Another example is breast cancer, which carries a lifetime risk of 5.53% (1 in 18).  The 6% increase in females exposed as infants raises that to 5.89% (1 in 17).

 

  • Lifetime leukemia risks in infant boys is estimated at roughly .60% (1 in 165). Adding in the extra Fukushima radiation exposure adds an additional 7% risk, which raises absolute risk to .64%  (1 in 156).

 

None of which is meant to minimize the overall impact of this nuclear accident in the least, or the devastating individual and family impacts that these additional cancers will bring.


But it does help to put these numbers in perspective.

 

Additional resources from WHO on the Fukushima radiation release include:

 

 

And lastly, as the press release notes, cancers are not the only serious long-term health consequences from the Fukushima disaster.

 

As well as the direct health impact on the population, the report notes that the psychosocial impact may have a consequence on health and well-being. These should not be ignored as part of the overall response, say the experts.

Friday, October 21, 2011

BMJ: Another Reassuring Report On Cell Phones & Brain Cancer

 

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# 5914

 

Yesterday, the British Medical Journal published the results of a follow up to large Danish cohort study that found no link between cell phone usage and an increase in brain tumors.

 

Although evidence for it has been scant, for a number of years some scientists have expressed concerns that prolonged exposure to cell phone RF (radio frequency) electromagnetic fields might cause certain types of head and neck cancers.

 

In 2010, the International Agency for Research on Cancer (IARC) released their long-delayed INTERPHONE report, which was unable to establish a link between cell phone use and brain tumors  (see The IARC Cell Phone Report).

 

Despite that initial finding, a year later (May 2011) the IARC released a statement (IARC Press Release N° 208) that listed mobile phone use in same `possibly’ carcinogenic hazard category as exposure to gasoline, engine exhaust and lead.

 

For details on this statement, you may wish to revisit IARC: Cell Phones `Possibly Carcinogenic’.

 

A couple of months later we saw a study that appeared in the Journal of the National Cancer Institute (see Reassuring Study On Cell Phones & Brain Cancer Risks) that found no link between cell phone use and brain tumors in children and adolescents.

 

While it is unlikely to be the final word on the subject, the study published yesterday in the BMJ follows up on the largest cohort study on mobile phone users to date.

 

And once again, the news is reassuring; long-term subscribers to cellular phone services showed no increase in brain or central nervous system tumors over non-subscribers. 

 

 

Use of mobile phones and risk of brain tumours: update of Danish cohort study

OPEN ACCESS

BMJ 2011; 343:d6387

Patrizia Frei, Aslak H Poulsen, Christoffer Johansen,  Jørgen H Olsen, Marianne Steding-Jessen,  Joachim Schüz

ABSTRACT

Participants All Danes aged ≥30 and born in Denmark after 1925, subdivided into subscribers and non-subscribers of mobile phones before 1995.

 

Main outcome measures Risk of tumours of the central nervous system, identified from the complete Danish Cancer Register. Sex specific incidence rate ratios estimated with log linear Poisson regression models adjusted for age, calendar period, education, and disposable income.

 

Results 358 403 subscription holders accrued 3.8 million person years. In the follow-up period 1990-2007, there were 10 729 cases of tumours of the central nervous system. The risk of such tumours was close to unity for both men and women. When restricted to individuals with the longest mobile phone use—that is, ≥13 years of subscription—the incidence rate ratio was 1.03 (95% confidence interval 0.83 to 1.27) in men and 0.91 (0.41 to 2.04) in women. Among those with subscriptions of ≥10 years, ratios were 1.04 (0.85 to 1.26) in men and 1.04 (0.56 to 1.95) in women for glioma and 0.90 (0.57 to 1.42) in men and 0.93 (0.46 to 1.87) in women for meningioma. There was no indication of dose-response relation either by years since first subscription for a mobile phone or by anatomical location of the tumour—that is, in regions of the brain closest to where the handset is usually held to the head.

 

Conclusions In this update of a large nationwide cohort study of mobile phone use, there were no increased risks of tumours of the central nervous system, providing little evidence for a causal association.

 

 

While this study was subject (as are all studies) to some limitations, In an accompanying BMJ editorial (Mobile telephones and brain tumours) professors Anders Ahlbom and Maria Feychting called the evidence in this report `reassuring’.

 

They cautioned, however, that `continued monitoring of health registers and prospective cohorts is still warranted.’

Thursday, July 28, 2011

Reassuring Study On Cell Phones & Brain Cancer Risks

 

 

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Photo Credit – Wikipedia

 

# 5822

 

Two months ago the World Health Organization’s International Agency for Research on Cancer (IARC) issued a new statement (IARC Press Release N° 208) that lists mobile phone use in same carcinogenic hazard category as exposure to gasoline, engine exhaust and lead.

 

For details on this announcement, you may wish to revisit IARC: Cell Phones `Possibly Carcinogenic’.

 

For a number of years some scientists had expressed concerns that prolonged exposure to cell phone RF (radiofrequency) electromagnetic fields might cause certain types of head and neck cancers.

 

And many researchers worried that children, teenagers, and young adults - who rank among the most fervent users of cell phones - could be at particular risk.

 

While it probably won’t settle the debate, today we’ve a new study that appears in the Journal of the National Cancer Institute that reassuringly found no link between cell phone use and brain tumors in children and adolescents.

 

 

Mobile Phone Use and Brain Tumors in Children and Adolescents: A Multicenter Case–Control Study

Denis Aydin, Maria Feychting, Joachim Schüz, Tore Tynes, Tina Veje Andersen, Lisbeth Samsø Schmidt, Aslak Harbo Poulsen, Christoffer Johansen, Michaela Prochazka, Birgitta Lannering, Lars Klæboe, Tone Eggen, Daniela Jenni, Michael Grotzer, Nicolas Von der Weid, Claudia E. Kuehni and Martin Röösli

 

The authors examined the medical records of 352 children aged 7-19  from Norway, Denmark, Sweden, & Switzerland with brain tumors. They conducted interviews with them to determine their cell phone usage, and compared this data to 646 control subjects.

 

The researchers found no statistically significant increase in the incidence of brain tumors among children and adolescents who were exposed to cell phone radiation, compared to those who were not.

 

Their conclusion:

 

The absence of an exposure–response relationship either in terms of the amount of mobile phone use or by localization of the brain tumor argues against a causal association.

 

 

Today’s study has some limitations. 

 

It is based primarily on self-reported data, the subjects had been using cell phones for an average of only 4 years, and much of this usage was likely text messaging -as opposed to voice calls – which would reduce radiation exposure to the head and neck.

 

Since it can take years – or even decades – for brain cancers to develop, the true health impacts from the stratospheric rise in cell phone use over the past decade may be difficult to accurately gauge for some time.

 

While today’s results are encouraging, the authors believe that it is important to continue to study the issue and be on the lookout for potential negative health effects related to cell phone use in children.

Tuesday, May 31, 2011

IARC: Cell Phones `Possibly Carcinogenic’

 

 

# 5588

 

 

It was just over a year ago that the the World Health Organization’s International Agency for Research on Cancer (IARC) released their long-delayed INTERPHONE report, which was unable to establish a link between cell phone use and brain tumors (see The IARC Cell Phone Report) .

 

For a number of years some scientists have expressed concerns that prolonged exposure to cell phone RF (radiofrequency) electromagnetic fields might cause certain types of head and neck cancers.

 

And researchers worried that children, teenagers, and young adults, who rank among the most fervent users of cell phones, could be at particular risk.

 

While reassuring, the 2010 INTERPHONE report wasn’t exactly an `All Clear’ on cell phone dangers. The study, the authors admitted, had limitations. And some scientists were less than mollified by their findings.

 

At the time, Dr Christopher Wild, Director of IARC warned that additional studies were warranted.  From the IARC press release of May, 2010:

 

"An increased risk of brain cancer is not established from the data from Interphone.

 

However, observations at the highest level of cumulative call time and the changing patterns of mobile phone use since the period studied by Interphone, particularly in young people, mean that further investigation of mobile phone use and brain cancer risk is merited."

 


Earlier this year we also saw a major report in the Journal of the American Medical Association that looked at the effects of RF signal exposure on brain activity (see JAMA: Cell Phone Use Stimulates Brain Activity).

 

Using PET scans researchers were able to prove that areas of the brain in close proximity to the antennas of activated cell phones demonstrated increased glucose uptake, indicating increased localized brain activity in response to the RF (radio frequency) emissions.

 

This study indicates that the prolonged use of a cell phone does affect brain activity. What all this might mean in regards to human health remains unknown for now.

 

Fast forward to today, and the IARC has released a new statement (IARC Press Release N° 208) that lists mobile phone use in same carcinogenic hazard category as exposure to gasoline, engine exhaust and lead.

 

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Given the popularity of (and our societal reliance upon) cell phones, this report – which classifies radio-frequency electromagnetic fields as possibly carcinogenic to humans (Group 2B) - is likely to spur a good deal of news coverage.

 

Group 1 carcinogens are those that are most strongly associated with cancer, like smoking and asbestos, and are considered the most dangerous.

 

Group 2a carcinogens are considered probably carcinogenic based on limited evidence of carcinogenicity in humans and sufficient evidence of carcinogenicity in experimental animals.

 

Group 2b carcinogens – where cell phones have now been ranked – are considered possibly carcinogenic, but evidence is limited in both humans and experimental animals.

 

For now, the evidence supporting a link between cell phones and certain types of brain cancer is limited. However, Dr Jonathan Samet, the overall chairman of the working group  states :

 

“ . . . the  evidence, while still accumulating, is  strong enough to support a conclusion and the 2B classification. The conclusion means that there could be some risk, and therefore we need to keep a close watch for a link between cell phones and cancer risk.” 

 

 

None of this proves that cell phones cause brain cancer.  Only that there is enough evidence to suggest a link to a specific type of cancer (glioma), and that more studies must be done.

 

Since it can take years – or even decades – for brain cancers to develop, the true health impacts from the stratospheric rise in cell phone use over the past decade may be difficult to accurately gauge for some time.

 

A full report on the IARC’s findings will be published over the next few days in The Lancet Oncology.

Tuesday, May 18, 2010

The IARC Cell Phone Report

 

 

 

# 4576

 

 

During my `back to the land’ phase - where I tried to tame 24 acres of Missouri wilderness (starting in 1995) - I lived in a remote area of the country where cell phone coverage was spotty at best.  

 

The only internet access was dial-up, and slow dialup at that.  On a good dry day, I might get 28.8K.  If it had rained recently . . . well, forget about it. 

 

So I missed out on a good deal of the technological revolution of the late 1990s, including cell phones.

 

When I finally returned to Florida (the statue of limitations having expired), I bought my first cell phone.  I don’t use it much, less than 90 minutes a month . . . but I’d hate to be without it. 

 

At age 56, I consider my cell phone a tool, even a bit of a luxury. 

 

But for my teenage grandnieces, they are practically implants. As necessary to them as oxygen or internet access. They burn more cell phone minutes in an average day than I do most months, along with sending hundreds of text messages every week.   

 

To them, cell phones are an integral part of their lives.   But as with almost everything, there’s a catch.  

 

Some scientists have concerns that prolonged exposure to cell phone RF (radiofrequency) electromagnetic fields could cause certain types of head and neck cancers. And researchers worry that children, teenagers, and young adults, who rank among the most fervent users of cell phones, could be at particular risk.

 

Yesterday, the International Agency for Research on Cancer (IARC) released their long-delayed INTERPHONE report, which was unable to establish a link between cell phone use and brain tumors

 

Which isn’t quite the same as saying that `no risk’ exists. The study, the authors admit, had limitations.

And some scientists are less than mollified by their findings.

 

This study leaves us with a good many unanswered questions.  From the Press Release:


Dr Christopher Wild, Director of IARC said: "An increased risk of brain cancer is not established from the data from Interphone. However, observations at the highest level of cumulative call time and the changing patterns of mobile phone use since the period studied by Interphone, particularly in young people, mean that further investigation of mobile phone use and brain cancer risk is merited."

 

First the IARC reports: a link to the (subscription) Journal article, the audio to yesterday’s press conference,  and the press release.

 

 

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WHO Press Conference - Interphone Study

18/05/2010 -
17 May 2010 16:00 - 16:45, WHO Headquarters, Geneva
Interphone study reports on mobile phone use and brain cancer risk
- Dr Christopher Wild, Director, IARC
- Dr Vincent Cogliano, Head, IARC Monographs Program
- Dr Elisabeth Cardis, Centre for Research in Environnement Epidemiology (CREAL)



Listen to the WHO Press Conference [mp3 28Mb]

 

 

Interphone Study Results published

17/05/2010 -
Brain tumour risk in relation to mobile telephone use: results of the INTERPHONE international case–control study
International Journal of Epidemiology 2010;1–20. doi:10.1093/ije/dyq079
The INTERPHONE Study Group
 
IARC Press Release No. 200

 

We also have this release from the FDA.

 

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The 4-year delay in presenting this data, the participation in the study by the cell phone industry, the methods used, and some aspects of this data’s presentation have caused some observers to view this study as frustratingly flawed.

 

From Reuters, we get this report calling into question the methods used in the study.

 

Cell phone cancer study shows problems with method

 

Kate Kelland, Health and Science Correspondent – Analysis

LONDON (Reuters) - The frustratingly inconclusive results from the world's biggest study so far into possible links between mobile phone use and cancer are symptomatic of problems that can dog scientific research like this.

 

Campaigners, cancer doctors and mobile phone manufacturers have been waiting for a decade to see if the findings of the study led by the respected International Agency for Research into Cancer (IARC) would finally provide an answer.

 

It didn't and experts say the biases and potential errors that rendered the study unreliable are difficult to avoid, yet very hard to adjust for.

(Continue . . . )

 

 

Time Magazine’s coverage of this report is even less reassuring.

 

 

Cell Phones and Cancer: a Study's Muddled Findings

By Bryan Walsh Monday, May. 17, 2010

It has become one of the most controversial questions in cancer medicine: can using a cell phone cause brain tumors? The federal government and the mobile industry have maintained there is no conclusive data to support a link between cell-phone radiation and cancer, but a growing band of scientists are skeptical, suggesting that the evidence that does exist is enough to raise a warning for consumers — before mass harm is done.

(Continue . . )

 

As then there’s this from New York Times

 

May 18, 2010, 7:03 am

Questions About Cellphones and Brain Tumors

By TARA PARKER-POPE

A long-awaited study of cellphone use and brain health has finally been released, but the data are raising more questions than answers.

The report is called Interphone, a 13-country study that amounts to the largest and longest study of whether extensive cellphone use increases risk for brain tumors. The study results, published in The International Journal of Epidemiology, were delayed by four years, reportedly after researchers disagreed over how to present the results.

(Continue . . .)

 

For now, the good news is there is no firm evidence linking cell phone use to an increased risk of cancer.  The bad news is, if such a link does exist, it could be another 10 years or more before a spike in head and neck tumors becomes measurable.

 

In the meantime, the FDA suggests that people who are worried about about cell-phone cancer risks should consider:

Minimizing RF Exposure


Although evidence shows little or no risk of brain  tumors  for most  long-term users of cell phones, FDA says people who want to reduce their RF exposure can:


•   reduce the amount of time spent on the cell phone
•   use speaker mode or a headset to place more distance between the head and the cell phone