Showing posts with label Shanghai. Show all posts
Showing posts with label Shanghai. Show all posts

Tuesday, April 07, 2015

Shanghai Reports 2nd Recent H7N9 Case

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Location Shanghai China

 

# 9906

 

 

After nearly a month of no news regarding H7N9 in China we’ve our second report out of Shanghai in three days, this time regarding a 37 year-old woman who is reportedly in critical condition. 

 

Although not mentioned in this CHP notification, the statement on the Shanghai Municipal Commission On Health And Family Planning  lists this woman from neighboring Jiangsu Province.

 

This from Hong Kong’s CHP.

 

CHP closely monitors additional human case of avian influenza A(H7N9) in Mainland 

The Centre for Health Protection (CHP) of the Department of Health (DH) is today (April 7) closely monitoring an additional human case of avian influenza A(H7N9) in the Mainland, and again urged the public to maintain strict personal, food and environmental hygiene both locally and during travel.


According to the Shanghai Municipal Commission of Health and Family Planning, the patient is a 37-year-old woman who is under treatment in critical condition.


To date, 620 human cases of avian influenza A(H7N9) have been reported by the Mainland health authorities in Guangdong (181 cases), Zhejiang (167 cases), Jiangsu (73 cases), Fujian (59 cases), Shanghai (47 cases), Hunan (26 cases), Anhui (24 cases), Xinjiang (10 cases), Jiangxi (10 cases), Shandong (six cases), Beijing (five cases), Henan (four cases), Guangxi (three cases), Jilin (two cases), Guizhou (two cases) and Hebei (one case).

(Continue . . .)

Sunday, April 05, 2015

HK CHP Notified Of H7N9 Case In Shanghai

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Location Shanghai China

 

# 9901

 

For nearly a month we’ve heard practically nothing regarding H7N9 cases from the Chinese mainland – case reports abruptly stopped on March 9th – a full two months earlier than previous waves would have led us to expect. 


Whether this represents a true halt in cases, or a change in the way the Chinese are choosing to report cases, isn’t known.  Even before this stoppage, getting timely reports out of China this winter has been difficult.

 

In any event, yesterday Xinhua News carried a report of an H7N9 case in Shanghai, and roughly 24 hours later there is an official notification published by Hong Kong’s CHP.

 

 

CHP closely monitors additional human case of avian influenza A(H7N9) in Mainland

The Centre for Health Protection (CHP) of the Department of Health (DH) is today (April 5) closely monitoring an additional human case of avian influenza A(H7N9) in the Mainland, and again urged the public to maintain strict personal, food and environmental hygiene both locally and during travel.


According to the Shanghai Municipal Commission of Health and Family Planning, a male patient aged 52 was hospitalised for management in stable condition.


To date, 619 human cases of avian influenza A(H7N9) have been reported by the Mainland health authorities in Guangdong (181 cases), Zhejiang (167 cases), Jiangsu (73 cases), Fujian (59 cases), Shanghai (46 cases), Hunan (26 cases), Anhui (24 cases), Xinjiang (10 cases), Jiangxi (10 cases), Shandong (six cases), Beijing (five cases), Henan (four cases), Guangxi (three cases), Jilin (two cases), Guizhou (two cases) and Hebei (one case).

(Continue . . .)

 

For more on the erratic reporting of avian flu cases by both China and Egypt this winter, you may wish to revisit More Than One Way to `Contain An Outbreak’.

Thursday, February 12, 2015

Shanghai & Guangdong Province Report H7N9 Cases

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# 9702

 

Guangdong Province reports 2 more cases to Hong Kong’s CHP, while Shanghai -   which appears to have been very proactive in their regulating and closing of live bird markets – reports only their 4th case of this third wave.

 

CHP closely monitors three additional human cases of avian influenza A(H7N9) in Mainland 

The Centre for Health Protection (CHP) of the Department of Health (DH) is today (February 12) closely monitoring three additional human cases of avian influenza A(H7N9) in the Mainland, and again urged the public to maintain strict personal, food and environmental hygiene both locally and during travel.

According to the notification of the Health and Family Planning Commission of Guangdong Province, a male patient aged 61 (in Guangzhou) died while another male patient aged 60 (in Shantou) is in critical condition and was hospitalised for management.

According to the Shanghai Municipal Commission of Health and Family Planning, the patient in Shanghai is a man aged 53 who was under treatment in critical condition.

To date, 568 human cases of avian influenza A(H7N9) have been reported by the Mainland health authorities, respectively in Guangdong (157 cases), Zhejiang (156 cases), Jiangsu (70 cases), Fujian (58 cases), Shanghai (45 cases), Hunan (24 cases), Anhui (17 cases), Xinjiang (10 cases), Jiangxi (nine cases), Shandong (six cases), Beijing (five cases), Henan (four cases), Guangxi (three cases), Jilin (two cases), Guizhou (one case) and Hebei (one case).

(Continue . . . )

 

Friday, January 23, 2015

Guangdong, Zhejiang & Shanghai Report H7N9 Cases

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# 9617

We continue to see sporadic reports of H7N9 coming out of the Chinese Mainland, with four cases reported today from three separate provinces.  

 

First stop, a notice from  Guangdong province – which has now reported 18 cases during this third H7N9 season – that informs us of two new cases.

 

Shantou, Zhaoqing City, one case of H7N9 cases were reported

2015-01-23 16:59:29   Ministry of Health and Family Planning  |      Health and Family Planning Commission of Guangdong Province January 23 briefing, Shantou, Zhaoqing were reported one case of H7N9 cases. 

Case 1 Humou, male, 68 years old, currently living Shantou area. January 23 diagnosed cases of H7N9, sicker patients currently in Shantou City, admitted to inpatient hospitals.


Case 2 Leimou, male, 4 years old, now living in Zhaoqing Sihui City, January 22 H7N9 cases diagnosed, the patient's condition is currently stable, in Zhaoqing City hospitals admitted to hospital.

 

For the second time this week Shanghai is reporting a new case as well.

 

Shanghai reported one new confirmed cases of human infection with H7N9 virus

Published: 2015-1-22

Shanghai Health and Family Planning Commission on January 22 briefing, Shanghai reported confirmed cases of the new H7N9 virus one case of human infection.

Patients, Chen, female, 75 years old, the city residence. Confirmed on January 22, patients in critical condition, is now in active treatment.

 

And lastly, Hong Kong’s CHP reports a `new’ case from Zhejiang Province.   Whether this case belongs to the group reported earlier this week by Xinhua News (see Zhejiang province has seen 14 cases this winter) or is a fresh case, is impossible to tell from the information provided.   Despite the Xinhua report, Hong Kong is only showing 8 new cases this winter in Zhejiang. 

 

CHP closely monitors four additional human cases of avian influenza A(H7N9) in Mainland

The Centre for Health Protection (CHP) of the Department of Health (DH) is today (January 23) closely monitoring four additional human cases of avian influenza A(H7N9) in the Mainland, and again urged the public to maintain strict personal, food and environmental hygiene both locally and during travel.


According to the notification of the Health and Family Planning Commission of Guangdong Province, the two cases involved a 68-year-old man in Shantou who was hospitalised for treatment in serious condition, and a 4-year-old boy in Zhaoqing who is in stable condition.


According to the Shanghai Municipal Commission of Health and Family Planning, the patient in Shanghai is a woman aged 75 who was under treatment in critical condition. In addition, according to the Health and Family Planning Commission of Yiwu Municipality, the patient in Yiwu, Zhejiang, is a man aged 45 who was under isolation and treatment.


To date, 489 human cases of avian influenza A(H7N9) have been reported by the Mainland health authorities, respectively in Zhejiang (146 cases), Guangdong (127 cases), Jiangsu (63 cases), Shanghai (44 cases), Fujian (28 cases), Hunan (24 cases), Anhui (17 cases), Jiangxi (nine cases), Xinjiang (nine cases), Shandong (six cases), Beijing (five cases), Henan (four cases), Guangxi (three cases), Jilin (two cases), Guizhou (one case) and Hebei (one case).

(Continue . . .)

  

The above listing showing 489 human cases represents only those cases hospitalized, tested, and diagnosed with the H7N9 virus and likely represents only a portion of the total number of cases. There are likely a number of mild, or even asymptomatic infections that go unnoticed, as well as serious or even fatal cases that are simply never diagnosed.

 

In 2013, a study appearing in  The Lancet (see Lancet: Clinical Severity Of Human H7N9 Infection) attempted to quantify that number - at a time when the `official count’ hovered around 130 cases -estimating `that between 1500 and 27 000 symptomatic infections with avian influenza A H7N9 virus might have occurred as of May 28, 2013’.

 

The accuracy of these estimates is unknown, but it is very likely that the official case counts under-represent the real burden of H7N9, perhaps by a sizable margin.


And this winter, the reporting of cases out of China seems more inconsistent than during previous H7N9 epidemic waves, with less detailed information provided, all of which adds a bit more `fog’ to obscure our view of this year’s outbreak.

Sunday, January 18, 2015

Guangdong & Shanghai Report New H7N9 Cases

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# 9594

 

The flow of H7N9 information out of China has been - to put it kindly - `variable’  this winter, with some provinces releasing information as they get it, and others waiting to release case reports in weekly or monthly summaries.  

 

We are also not seeing the kind of detail (onset dates, possible exposures, etc.) this year that we often saw released during the first two H7N9 waves, complicating the creation of reliable line-list reports.

 

Although I haven’t found anything on the Guangdong Health Department website, we have this first report on two new Guangdong cases reported by Xinhua News.

 

Guangdong soared two H7N9 cases

CNA -January 18, 2015 19:55 pm

(CNA Taipei 18 (Xinhua)) today informed the Guangdong Provincial Health and Family Planning Commission, Shenzhen, Shanwei were a new confirmed cases of avian influenza virus H7N9. In which a man in critical condition, another girl of clinical symptoms disappeared already.

Xinhua News Agency reported, H7N9 cases confirmed in Shenzhen for 66-year-old man surnamed Chen patients, now living Longhua District, renal insufficiency, diabetes and other diverse history, the 17th confirmed, is currently in critical condition at a hospital in Shenzhen, treatment .

Shanwei confirmed H7N9 cases was a year and a half of Huang girl now living Shanwei City, on the 13th specimen was collected specimens, 16 were confirmed as H7N9 positive.

But reported that, after treatment, clinical symptoms Huang girls have disappeared, and then after 17 specimen samples collected and tested, has been restored to a negative reaction.

 

 

Along with this brief report from the Shanghai Department of Health & Family Planning.

 

Shanghai reported one case of H7N9 virus infection confirmed cases

January 17, 2015

Shanghai Health and Family Planning Commission on January 17 briefing, Shanghai reported one case of H7N9 virus infection confirmed cases.

Patients Zhang, male, 69 years old, the city residence. Confirmed on January 17, is now in active treatment.

 

Although there is a high degree of uncertainty over just how many cases China is seeing right now, so far there are no indications that the H7N9 virus is spreading any more efficiently this year than we’ve seen in previous years.

Saturday, December 06, 2014

Shanghai Reports H7N9 Case

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Credit Wikipedia


# 9418

 

 

A brief announcement today from the Shanghai Department of Health and Family Planning gives us the bare-bones details on what is their first reported case of H7N9 case of this fall. During the first two waves (spring 2013, winter-spring 2014), Shanghai was the fourth most active region in China, reporting 41 human infections.


With more than 24 million people, Shanghai is China’s most populous city, and was one of the first regions to report H7N9 in the spring of 2013.

 

While we watch all human infections with novel influenza viruses with concern, H7N9 has spread faster to humans than any other avian flu virus, and studies suggest it continues to evolve towards becoming a `mammalian adapted’ virus. Over the past month we’ve begun to see an uptick in human infections in China, and more cases are expected as we get deeper into the winter season.

 

 

Shanghai 1 new confirmed cases of human infection with H7N9 avian influenza

Published: 2014-12-6

Shanghai Health and Family Planning

December 6, 2014

Shanghai Health and Family Planning Commission Dec. 6 briefing, Shanghai new confirmed cases of H7N9 avian influenza case of human infection.

Patients Sheng, male, 38 years old, the city residence. Confirmed on December 6, is now in active treatment.

Thursday, January 23, 2014

Zhejiang, Shanghai & Guangdong Announce H7N9 Cases

 

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# 8208

 

With just  a week to go before China’s New Year’s Eve celebrations really take off, the number of new H7N9 cases continues its slow rise, with the greatest concentration of cases coming from Zhejiang province.  

 

Overnight Crof had some good news to report in Zhejiang: Shaoxing wet markets closed over H7N9, where - at least in the city of a little more than 4 million in Zhejiang province (ttl pop. 54 million) - city officials are pulling the plug on live markets in an attempt to curb the transmission of the virus.

 

Despite the successful mitigation last spring, as described in The Lancet: Poultry Market Closure Effect On H7N9 Transmission, for the most part, market closures announced in Eastern China this year have been temporary to allow for `disinfection days’.

 

Today Zhejiang breaks its streak of 6 consecutive days of reporting 3 cases of H7N9 by  reporting 5.

 

Zhejiang Province, five new cases of human H7N9 avian influenza infection

Source: Ministry of Health and Family Planning Commission

January 23, 2014

Zhejiang Provincial Health and Family Planning Commission January 23 briefing, the province today five new cases of human infection of H7N9 avian influenza.


1, patients Moumou, female, 66 years old, retired, Shaoxing City people. January 22 confirmed human infection of H7N9 avian influenza. Is now in critical condition, a hospital for treatment in Shaoxing.


2, patients with the surname Wang, female, 71 years old, retired, Hangzhou Riverside area people. January 22 confirmed human infection of H7N9 avian influenza. Is now in critical condition, in Hangzhou, a hospital for treatment.


3 patients Xu X, male, 71 years old, farmer, Cangnan County of Wenzhou people. January 22 confirmed human infection of H7N9 avian influenza. Now the condition is severe, treatment at a hospital in Wenzhou.


4, the patient Moumou, male, 59 years old, workers, Yinzhou District, Ningbo people. January 22 confirmed human infection of H7N9 avian influenza. Now the condition is severe, in Ningbo, a hospital for treatment.


5, the patient Hu Moumou, female, 63 years old, farmer, Huzhou, Deqing County. January 22 confirmed human infection of H7N9 avian influenza. Is now in critical condition, in Hangzhou, a hospital for treatment.

 

Shanghai, which ranks second in the number of H7N9 cases reported to date, announces a new case as well.

 

Shanghai 1 new confirmed cases of human infection with H7N9 avian influenza

Published :2014 -1-23

Shanghai Health and Family Planning Commission January 23 briefing, Shanghai reported new confirmed cases of H7N9 avian influenza case of human infection.

Patients, Qin Moumou, female, 61 years old, the city residence. Confirmed on January 22, is now in active treatment.

According to state regulations, from November 1, 2013 the city began infected with H7N9 avian influenza has been incorporated into human B infectious management.

 

And our last stop (for now), Guangdong Province also reported a fresh case this morning.

 

Province added one case of human infection of bird flu H7N9 two cases were cured

2014-01-23 17:30:22 Ministry of Health and Family Planning Commission | 

Health and Family Planning Commission of Guangdong Province on January 23 briefing, Shenzhen 1 new confirmed cases of human infection with H7N9 avian influenza, the province there are two cases cured.


Patients Zhang, female, 34 years old, currently residing in Baoan, Shenzhen, January 23 confirmed cases of human infection of H7N9 avian influenza, the patient is currently in critical condition in Shenzhen designated hospital admission.

Also, Guangzhou City on January 18 confirmed cases Panmou and Foshan City on January 10 confirmed cases Ryu were cured and discharged on January 22. So far, the province a total of seven cases of human infection with the H7N9 avian flu cured.

 

It is possible we will see additional cases announced later in the day.

 

Despite this daily parade of new cases, thus far these cases appear to be sporadic in nature, and without direct links to one another, and so we’ve no evidence of sustained or efficient human-to-human transmission of this virus.

Monday, January 20, 2014

Shanghai, Zhejiang Report New H7N9 Cases (2 Fatal)

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# 8189

 

The end-of-day H7N9 reports for Monday are beginning to filter in and thus far we have two fatal cases – including an Emergency Room doctor – from Shanghai and, for the 12th day running, Zhejiang province is reporting new cases as well.  Additional case reports may appear later in the day.

 

For now, our first stop is Shanghai, where an two people who died on Saturday were later determined to have had the H7N9 infection. 

 

In the most high profile case – that of an ER doctor who worked at Pudong New Area People's Hospital – media reports suggest his early symptoms were atypical for influenza, consisting primarily of fever for the week before his death (see Atypical Influenza (H5N1,H7N9, pH1N1) Presentations)

 

According to a Shanghai Daily report overnight (see Doctor suspected to have died from H7N9), the doctor worked his shifts up until Friday despite his ongoing fever, but his condition suddenly deteriorated on Friday and he died Saturday morning of pneumonia and respiratory failure.  How, and where, he acquired the infection is unknown.

 

As we have only limited evidence of human-to-human transmission of the virus, it is impossible to even guess whether this doctor might have passed the virus on to others while he worked in the emergency room. 

 

His co-workers were likely at greatest risk, and presumably will be monitored.

 

This somewhat less detailed report from Shanghai’s Ministry of Health and Family Planning.

 

Shanghai 2 new confirmed cases of human infection with H7N9 avian influenza

Published :2014 -1-20

Shanghai Health and Family Planning Commission January 20 briefing , Shanghai reported new confirmed cases of H7N9 avian flu two cases of human infection .


Patients First, Moumou , male, 31 years old , Shanghai household registration , medical personnel . Patients were around at 4:00 on January 18 , after she died . January 19 , samples of laboratory test results for patients with H7N9 avian influenza virus nucleic acid positive clinical expert by the municipal cases based on clinical manifestations , laboratory test results and epidemiological investigation , the overall judgment of the people infected with H7N9 avian case confirmed cases of influenza .

Two patients , Wu Moumou , male, 77 years old , Shanghai household registration , farmers. Patients were around at 0:00 on January 18 , after she died . January 19 , samples of laboratory test results for patients with H7N9 avian influenza virus nucleic acid positive clinical expert by the municipal cases based on clinical manifestations , laboratory test results and epidemiological investigation , the overall judgment of the people infected with H7N9 avian case confirmed cases of influenza .

Since July this year, the city reported a total of confirmed cases of human infection with H7N9 avian influenza , are sporadic cases . Close contacts of all cases , have been observed to implement health measures , the current situation is no exception .

According to state regulations , from November 1, 2013 the city began infected with H7N9 avian influenza has been incorporated into human B infectious management.

 

Zhejiang Province meanwhile is reporting three new cases, bringing to 27 the total number reported out of that province since the start of 2014.

 

Zhejiang Province, three new cases of human infection of bird flu H7N9

Release date :2014 -01-20
Source: Ministry of Health and Family Planning Commission


January 20, 2014

Zhejiang Provincial Health and Family Planning Commission January 20 briefing, the province today added three cases of human infection with H7N9 avian influenza.

1, patients Jin Moumou, female, 71 years old, farmer, Yuhang District, Hangzhou people. January 19 confirmed human cases of avian influenza H7N9 infection. Is now in critical condition, in Hangzhou, a hospital for treatment.

2, the patient Fang Moumou, male, 63 years old, farmer, Longyou County, Zhejiang Province, Jiaxing County is now live. January 19 confirmed human cases of avian influenza H7N9 infection. Now the condition is severe, treatment in a hospital in Hangzhou.

3, the patient Cao Moumou, male, 55 years old, farmer, Yinzhou District, Ningbo people. January 19 confirmed human cases of avian influenza H7N9 infection. Is now in critical condition, a hospital for treatment in Ningbo.

 

Despite enhanced awareness in hospitals across Eastern China, it is apparent that some of these cases are not being diagnosed until they have progressed to a severe level of  illness, or even after the patient’s death.  Not only does this bode ill for the individual patient, it allows potentially infectious patients to expose others to the virus.


The difficulty is, that in its early stages, H7N9 infection looks like any other respiratory or viral illness.  And this time of year, literally millions of people across China (and the globe) are experiencing typical winter respiratory infections. In an ideal world, every flu-like case would be tested for novel influenza, but logistically, that simply isn’t going to happen.

 

Unknown also is how many mild, or even asymptomatic H7N9 infections are going undetected.  While we see a high percentage of severe illness among the cases that are diagnosed, we really have no idea how much of the big picture we are seeing.


While this daily parade of new cases is concerning, thus far we haven’t seen compelling evidence of sustained or efficient human-to-human transmission of this virus.

 

The virus, however, continues to evolve, and so we continue to track these cases carefully, looking for any signs that its behavior has changed.

Wednesday, January 15, 2014

Guangdong, Shanghai & Zhejiang Add New H7N9 Cases

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Credit CDC

 

 

 

# 8173

 

As usual, reports are coming in piecemeal this morning from the various provinces in China where new H7N9 cases have been detected.  Thus far, we’ve 2 official announcements (2 cases in Guangdong Province, 1 in Shanghai) and media accounts of another case (not yet posted on the MOH site) in Zhejiang Province.

 

 

Guangdong Province to add two cases of human infection with H7N9 bird flu

2014-01-15 16:03:46 Ministry of Health and Family Planning Commission 

Health and Family Planning Commission of Guangdong Province on January 15 briefing, the province confirmed two cases of human infection with the H7N9 avian influenza.

Case 1 patient Xie Moumou, male, 48 years old, currently residing in the town of Nanhai District, Foshan City. January 15 confirmed human cases of avian influenza H7N9 infection. Currently in critical condition, in Foshan City, the designated hospital for treatment.


Case 2 patients surname Wang, male, 55 years old, now living Zhangmutou. January 15 confirmed human cases of avian influenza H7N9 infection. Currently in critical condition, in Shenzhen designated hospital for treatment.

 

 

Confirmed cases of H7N9 avian influenza reported one case of human infection in Shanghai

Published :2014-1-15

Shanghai Health and Family Planning Commission January 15 briefing, H7N9 bird flu case in Shanghai, reported one case of human infection.


Patients Wu Moumou, male, 35 years old, Ningbo City, Zhejiang Province domicile. Confirmed on January 4, is now a city hospital for treatment.

According to state regulations, from November 1, 2013 the city began infected with H7N9 avian influenza has been incorporated into human B infectious management.

 

 

While it has yet to appear on the Zhejiang MOH website, this reports of this next case are appearing in multiple media outlets.  If confirmed, this would be the 7th day in a row that Zhejiang Province has reported new cases.

 

  This from CCTV (h/t Tetano on FluTrackers)

 

 

Zhejiang new case of human infection of bird flu H7N9

At 15:09 on January 15, 2014
Source: CCTV

0 People involved 0 Comment

CCTV News [Zhejiang add one case of human infection with H7N9 avian influenza] Zhejiang Health and Family Planning Commission today informed, Zhejiang confirmed one case of human infection with the H7N9 avian flu yesterday. Patients Hou Moumou, male, 41 years old, farmer, now living in Hangzhou Yuhang District, yesterday confirmed cases of human infection of H7N9 avian influenza, is in critical condition, in Hangzhou, a hospital for treatment

 

 

We will probably see a more complete round up of today’s cases from Hong Kong’s CHP later today.

 

Despite the continual rise in cases, thus far they appear to be sporadic, and few have been epidemiologically linked.

 

Meaning that while some small clusters have occurred, there are no signs that the virus has learned to spread from human-to-human in an efficient or sustained fashion.

Saturday, January 04, 2014

Shanghai Reports New H7N9 Case

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Location Shanghai China

 

 

# 8126

 

In a very brief announcement on their website, Shanghai’s Municipal Commission of Health & Family Planning, has reported their first H7N9 case of 2014 – that of an 86 year-old man who is currently hospitalized.  First the Shanghai statement (machine translated), followed by Hong Kong’s publication of the notification, after which I’ll return with more. 

 
Confirmed cases of H7N9 avian influenza reported one case of human infection in Shanghai

Shanghai Health and Family Planning Commission January 3 briefing, H7N9 bird flu case in Shanghai, reported one case of human infection.

Patients Zhou Moumou, male, 86 years old, the city residence. Confirmed on January 3, is now a city hospital for treatment.

According to state regulations, from November 1, 2013 the city began infected with H7N9 avian influenza has been incorporated into human B infectious management.

 

From Hong Kong’s CHP:

Additional human case of avian influenza A(H7N9) in Shanghai verified by NHFPC

The Centre for Health Protection (CHP) of the Department of Health (DH) today (January 4) verified with the National Health and Family Planning Commission (NHFPC) an additional human case of avian influenza A(H7N9) in Shanghai affecting a man aged 86.

The case was confirmed yesterday (January 3) and the patient is currently admitted to a local hospital for treatment.

To date, a total of 145 human cases of avian influenza A(H7N9) have been confirmed in the Mainland, including Zhejiang (51 cases), Shanghai (34 cases), Jiangsu (28 cases), Guangdong (six cases), Jiangxi (six cases), Fujian (five cases), Anhui (four cases), Henan (four cases), Beijing (two cases), Hunan (two cases), Shandong (two cases) and Hebei (one case).

The CHP will follow-up with the Mainland health authorities for more case details.

"Locally, enhanced disease surveillance, port health measures and health education against avian influenza are ongoing. We will remain vigilant and maintain liaison with the World Health Organization (WHO) and relevant health authorities. Local surveillance activities will be modified upon the WHO's recommendations," a spokesman for the DH remarked.

All border control points (BCPs) have implemented disease prevention and control measures. Thermal imaging systems are in place for body temperature checks of inbound travellers. Suspected cases will be immediately referred to public hospitals for follow-up investigation.

(Continue . . . )

 

Although it seems as if we’ve been discussing H7N9 for a long time, in truth, we first learned of this emerging virus about 9 months ago, when China’s CDC announced the first two cases from Shanghai (see  More Details Emerge On Shanghai H7N9 Case) on March 31st.

 

In the two months that followed, we learned that cases had begun to appear in February of 2013, and continued to appear until aggressive controls on live bird markets were imposed in April and May (see The Lancet: Poultry Market Closure Effect On H7N9 Transmission).

 

After a quiescent summer, as expected (see Chinese CDC: Be Alert For H7N9), colder fall and winter temperatures have brought a resurgence in the number of human infections being reported.  As we saw last spring, thus far, these appear to be sporadic cases, without any epidemiological evidence of efficient and sustained transmission.

 

Of concern is that Chunyun - or the Spring Festival travel season - begins about 15 days before the Lunar New Year (January 31st this year) and runs for about 40 days total, is only a couple of weeks away.  Over these six weeks more than 2 billion passenger journeys will be made (mostly via crowded rail and bus) across Asia.

 

During this time poultry sales in China also reach record levels, as duck and chicken are popular dishes served during these reunion dinners.  It is probably no coincidence that the first outbreak of the H7N9 virus emerged during and just after the last (2013) Spring Festival, and that has public health officials concerned.

 

On December 1st, we saw a preventative measure announced - Shanghai To Close Poultry Markets Over Lunar New Years To Curtail H7N9 - but the plan was to keep live bird markets open up until the Lunar New Year’s Eve – January 31st.   Whether today’s announcement will influence that decision is something we’ll have to wait to see.

 

Over the years we’ve seen occasional attempts to close live bird markets in Asia – as they are often linked to the spread of avian (and other) pathogens to humans - only to be met with tremendous public resistance (see 2009 blog China Announces Plan To Shut Down Live Poultry Markets In Many Cities).  Their ambitious plans,  announced 4 years ago to `shut live poultry markets in all large and medium-sized cities throughout China’, obviously never happened.

 

Purchasing live market birds is deeply ingrained in Asian culture, and in a part of the world where refrigeration isn’t always available, it reassures the buyer that the bird is both fresh and healthy. 

 

While concerns run high that Chunyun could usher in another mini-epidemic of H7N9 cases like we saw last spring  – and patient reports and laboratory testing have suggested it is unusually well-adapted to mammalian physiology (see mBio: H7N9 Naturally Adapted For Efficient Growth in Human Lung Tissue)  – thus far this virus has failed to demonstrate the ability to transmit efficiently among humans.

 

And it may be that it never will.  

 

But – like H5N1 – over time this virus will likely mutate and evolve into multiple clades (see EID Journal: The Expanding Variants Of H5N1). And we could discover H7N9 version 2.0 (or beyond) to be better adapted to humans than this first incarnation.

 

So anything that can be done to reduce the spread – and opportunities for adaptation –of the H7N9 virus today could go a long ways towards preventing a possible pandemic tomorrow. 

 

Complicating matters, this virus is a stealthy one - at least in birds - making eradication and containment more difficult than with other more pathogenic avian viruses. Often, the only indication we get that local birds are infected is when a human in contact with them falls ill.

 

Which illustrates the importance of surveillance and testing of humans with flu-like symptoms over the coming months in China, if this virus is to be detected and contained.

Sunday, December 01, 2013

Shanghai To Close Poultry Markets Over Lunar New Years To Curtail H7N9

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Photo Credit – FAO

 

# 8023

 

 

Each winter the largest annual migration of human beings commences when millions of  people return home to attend a reunion dinner with their families on the eve of the lunar New Year.  As you might imagine, these mass migrations (along with mass gatherings) are of considerable interest to public health officials and epidemiologists.

 

Chunyun, or the Spring Festival travel season, begins about 15 days before the Lunar New Year and runs for about 40 days total, during which time more than 2 billion passenger journeys will be made (mostly via crowded rail and bus) across Asia.

 

During this time poultry sales in China often reach record levels, as duck and chicken are popular dishes served during these reunion dinners.  It is probably no coincidence that the first outbreak of the H7N9 virus emerged during and just after the last (2013) Spring Festival.

 

The outbreak was finally brought under control by the mass closing of live poultry markets in April and May.  But since then, those markets have reopened, and the concerns run high that we could see a recurrence of this outbreak this winter. 


Today, Shanghai authorities have announced that live poultry  markets will be closed on January 31st (the Lunar New Year) and will remain closed until the end of April. I would imagine that the trade in poultry will be very brisk those last few days of January.  For now, this policy only appears to be enacted in Shanghai.  

 

Poultry market to shut over bird flu fears

By Cai Wenjun and Zhao Wen | December 2, 2013, Monday |

Shanghai will suspend live poultry trading from January 31, the first day of the Chinese Lunar New Year, until April 30 to prevent a recurrence of the bird flu.

The suspension will be an annual feature for the next five years, dependent on the evaluation and warning of the bird flu and the seasonal onset, according to a joint statement issued by the Shanghai Agricultural Commission and the Shanghai Commerce Commission.

All the designated wholesale and retail markets will be banned from trading in poultry and violators face hefty fines between 10,000 yuan (US$1,641) and 30,000 yuan under a new rule that took effect in June.

Unlicensed street vendors who sell live poultry during the period will be punished by urban management teams.

Poultry from other cities and provinces must be sent to designated slaughterhouses and cannot enter the local market directly, it said.

(Continue . . . )

 

Mass gatherings and migrations always raise concerns over infectious disease transmission, something we watched carefully during this year’s Hajj.   Luckily, there appears to have been only a small handful of MERS cases reported during that time. 

 

Still, events like Carnival in Rio, The Super Bowl, Chunyung, and Mardi Gras all keep public health officials on their toes.

 

In 2010, in The Impact Of Mass Gatherings & Travel On Flu Epidemics , we looked at a study  published in BMC Public Health, that looked at and attempted to quantify the impacts of mass gatherings and holiday travel on the spread of an influenza epidemic.


And in 2011, in Viruses With A Ticket To Ride, we looked at a study that  appeared in BMC Infectious Diseases, that looked at the incidence of ARI (Acute Respiratory Infection) presenting within 5 days of train or tram travel in the UK. They found that recent  bus  or  tram  use  within  five  days  of  symptom  onset  was  associated  with  an  almost  six-fold  increased  risk  of  consulting  for  ARI.

While seemingly a strong finding, this observational study was limited by its small size, the fact that it was only conducted in a single location (Nottingham, UK), and that it was conducted during a normal flu season, not a pandemic.

 

It will be interesting to see if other cities and provinces in Easter China follow suit, and what – if any – effect this step will have in mitigating the spread of the H7N9  (or any other avian virus) this winter.

Thursday, June 20, 2013

H7N9: Shanghai Reopens Live Poultry Markets

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Photo Credit – FAO

 

 

# 7412

 

For reasons that are not entirely clear – but that many have attributed to warmer summer temperatures and the mass closure of live poultry markets – China’s spring H7N9 outbreak had lost steam and dissipated by the middle of May.

 

The source of this outbreak, which infected at least 132 individuals and produced 37 deaths (see WHO Human infection with avian influenza A(H7N9) virus – update) has never been determined, but a substantial portion of these infections appeared to be linked to live poultry markets.

 

While only a handful of market birds ever tested positive for the virus, one of the first steps taken in Shanghai - and across much of Eastern China  - was to shutter all of their live poultry markets.

 

Within weeks the number of new cases had dropped precipitously, seemingly confirming the wisdom of this decision. 

 

Today, roughly 10 weeks after they were first closed, Shanghai allowed the reopening of roughly 200 (of their 461) live markets. Chickens, pigeons, and quail may be sold (but not ducks & geese), and strict daily disinfections are required.

 

China’s health authorities (and indeed, the rest of the world) will be watching closely to see if this limited, highly regulated, re-opening of markets reintroduces the virus to the community.

 

Given that avian flu viruses historically spread best in cooler weather, the real test for these new poultry market regulations may not come until next winter and spring.

 

This from today’s Shanghai Daily.

 

Live poultry marts reopen as H7N9 bird flu ban lifted

By Ke Jiayun  |   2013-6-20  |LIVE poultry will be allowed for sale in local markets starting today, almost 10 weeks after the city imposed a ban to prevent the spread of H7N9 bird flu.

 

Live chickens, pigeons and quails will be for sale, while live ducks and geese still are prohibited, officials said yesterday. They did not say when other types of live poultry might be sold.

 

Retail outlets qualified to sell live poultry must follow regulations strictly and disinfect their spaces regularly. The stores will be separated from the other sections of markets and have their own entrances.

 

The number of live poultry retail stores in the city will shrink from 461 before the outbreak to 200. One of the three main wholesale poultry markets will remain closed while the two others, in the Pudong New Area and Songjiang District, will reopen after test results are accepted by authorities.

 

The city is considering cutting back on live poultry sales every year between Spring Festival and the end of April. A preliminary proposal would ask designated retail outlets to close one day per week, while wholesale markets would close one or two days a week.

(Continue . . .)

Monday, April 15, 2013

H7N9: 1 New Case Zhejiang Province, 0 In Shanghai

 

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Location Shanghai China

 


# 7140

 


After a three-day span that saw the number of new H7N9 cases surge by roughly 50%, the number of new cases reported this morning has dropped off considerably.

 

While welcome news, it is far to soon to say whether this represents a trend.

 

We saw an earlier report of a single case in Jiangsu Province, and now we have a single case in Zhejiang.  Additionally, Shanghai announced no new cases today.

 

This from the Zhejiang Health Department.

 

New cases of human infection with the H7N9 avian flu cases in Zhejiang province

Date :2013 -04-15
Source: Provincial Health Department Zhejiang

Provincial Health Department informed that, as of April 15, 2011 16:00 April 15, Zhejiang new case of human infection of H7N9 avian influenza.

Patients with Wang, female, 68 years old, farmer, who lives in Huzhou onset on April 3, now a hospital treatment. Testing by the provincial CDC, human infection with the H7N9 avian influenza virus nucleic acid positive patient specimens. My Office Organization expert on the clinical manifestations, epidemiological data and laboratory test results to discuss the diagnosis of human infection confirmed cases of the H7N9 avian flu. Currently, the patient was seriously ill, the hospital is actively treatment.

 

 

The next announcement from Shanghai is notable for two reasons; because no new cases were reported and because testing seems to be having difficulty finding the virus among local poultry or their environment.

 

This from Xinhua News.

 

Shanghai today no new human cases of infection with the H7N9 avian flu

April 15, 2013 18:40:47

According to Voice of China "peak evening news" reports, according to the Planning Commission of Shanghai Wei Bulletin, 17:00 As of today, the city no new human cases of infection with the H7N9 avian flu.

 

Today, the Shanghai animal disease prevention and control center of Shanghai, poultry farms and other 2212 samples of avian influenza virus nucleic acid detection, and the results were negative. The business sector accumulated ban all kinds of street market, live poultry, birds transaction point 125.

 

Despite strong suspicions that poultry are heavily involved in the transmission of this virus, and some birds have tested positive, we continue to see a lot of negative test results come back from poultry and their environment.

Saturday, April 13, 2013

H7N9: 1 Shanghai Family Contact, 2 in Zhejiang Province – Total 49

 

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Regions Reporting H7N9

 

 

# 7126

 

In addition to the `big news’ that a case of H7N9 has turned up in China’s Capital, Beijing, we also have word this morning of a man diagnosed in Shanghai, who’s wife was diagnosed last week (and who died April 3rd).

 

While it is certainly possible that these two cases had a common environmental or poultry exposure, it does once again raise the question over possible human-to-human transmission.

 

This (machine translation) the People’s Daily:

 

Shanghai same home to two cases of human infection with the H7N9 avian influenza confirmed cases

Apr. 13, 2013 17:08
Source:
People's Daily

Wang Youjia) Shanghai, People's Daily, Shanghai, April 13 (same family of two cases of human infection with the H7N9 avian influenza confirmed cases.

 

Communications According to Shanghai Methodist Planning Commission, the then Shanghai Municipal Center for Disease Control report on April 11, found one cases of laboratory detection of the H7N9 avian influenza virus positive patients. The patients by the the municipal expert group consultation. As of 16:00 this afternoon, a total of 21 cases of human infection with the H7N9 avian influenza confirmed cases, of which 7 died, and another 13 cases are isolated treatment.

 

The new cases are as follows: Gumou, male, 56 years old, the people of Shanghai. Fatigue, fever and other symptoms start to appear on April 1, April 3, 4, two to the Huashan Hospital doctor, go to the 4th treatment of the Shanghai Public Health Clinical Center. Currently being further treatment. April 11 test results positive for H7N9 avian influenza nucleic acid.

 

His wife than some fever and other symptoms on March 27, April 4 patients collected respiratory specimens were found positive for H7N9 avian influenza virus nucleic acid. Shanghai Wei Planning Commission said that, based on currently available information, insufficient determine Gumou incidence is due to an infection caused by.

 

The experts believe that the emphasis on the study of clusters of cases of human infection with the H7N9 avian influenza, and strengthen co-exposure cases, the pathogenic characteristics of the virus and the study of the natural history of disease.

And in Zhejiang Province, two new cases were reported overnight, which – if my slightly sleep-deprived mind hasn’t led me astray – puts us now at 49 confirmed cases, and 11 fatalities.

 

Additional two cases of human infection with the H7N9 avian flu cases in Zhejiang province

Date :2013 -04-13
Source: Health Department

Zhejiang Provincial Health Department

April 13, 2013

Zhejiang Provincial Health Department Bulletin, as of April 13, 2011 14:00 April 13, Zhejiang add two cases of human infection with the H7N9 avian influenza.

 

Patients Kwak, male, 65 years old, retired, and now lives in Hangzhou. Incidence on April 3, to Hangzhou, a hospital in the 9th. April 13, Zhejiang Province CDC report patient specimens positive for H7N9 avian influenza virus nucleic acid.

 

Patients with Jo, male, 38 years old, workers, now living in Hangzhou. Disease, to a hospital on the evening of 11 April 6. April 13, Zhejiang Province CDC report patient specimens positive for H7N9 avian influenza virus nucleic acid.

 

I Office organization expert clinical manifestations of these two patients, discuss the epidemiological data and laboratory test results, the diagnosis of human infection confirmed cases of the H7N9 avian flu. Currently, more than two patients in critical condition, have been transferred to a hospital at the provincial level, being rescue work.

Wednesday, April 10, 2013

Shanghai Reports Two New H7N9 Cases – Total Now 33

 

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Credit Wikipedia

 

# 7107

 

Two more cases of H7N9 infection are being reported this morning, which in addition to my earlier report China: Reports Of 3 New H7N9 Cases, makes 5 new cases today. 


First, a brief announcement from Xinhua News, followed by the press release from the Shanghai Health Department.

 

Two more H7N9 infection cases reported in Shanghai

English.news.cn   2013-04-10 18:47:25

SHANGHAI, April 10 (Xinhua) -- Two more cases of H7N9 bird flu infections were reported on Wednesday in Shanghai Municipality, bringing the total number of infected people in the country to 33, health authorities said.

 

The following is from the Shanghai Health and Family Planning Commission.

 

Shanghai today, two cases of new confirmed cases of human infection with the H7N9 avian influenza patients discharged from hospital today

 

Deadline 17:00, the city newly diagnosed cases of human infection of H7N9 avian influenza. At present, a total of 15 cases of human infection with the H7N9 avian influenza confirmed cases, of which 5 died, the other nine cases being treated in isolation, 1 patient was discharged today (the 10th).

 

2 new cases as follows:

 

The patients named Ma, female, 76 years old, the people of Shanghai, retirees. Patients 1 day 21 discomfort, cough, sore throat, fatigue symptoms. April 2 self-test temperature of 39 ℃, to self-medicate symptoms without relief to the Huashan hospital on April 5, the diagnosis of pneumonia. On the evening of April 9, City CDC test results for the H7N9 avian influenza virus nucleic acid positive.

 

Organization of municipal clinical expert group in accordance with the relevant requirements, the City Health and Family Planning Commission to discuss the cases, the diagnosis of the cases of human infection of H7N9 avian influenza confirmed cases. Patients are medically stable, in being active treatment. After investigation, the close contacts of cases of a total of four people have been implemented under medical observation, until now, were not unusual.

 

Patients with Kim, female, 81 years old, the people of Shanghai, farmers. Patients April 4 no obvious incentive diarrhea, fever, to Pudong hospital, diagnosed with acute enteritis. No significant improvement in the disease, the patient afterwards to Pudong hospital referral, was diagnosed with a right lower pneumonia. On the evening of April 9, City CDC test results for the H7N9 avian influenza virus nucleic acid positive.

Organization of municipal clinical expert group in accordance with the relevant requirements, the City Health and Family Planning Commission to discuss the cases, the diagnosis of the cases of human infection of H7N9 avian influenza confirmed cases. Patients are medically stable, in being active treatment. After investigation, the close contacts of the cases, a total of five have been implemented under medical observation, until now, were not unusual.

 

 

 

While new cases - with onset dates well into the first week of April - continue to turn up, the source and manner of infection remains uncertain. 

 

For now, there is no evidence of sustained or ongoing human-to-human transmission.

 

But as Declan Butler wrote yesterday in the Nature article Urgent search for flu source, it is imperative that investigators get a handle on where this virus is coming from, and how it is being transmitted to humans.

Tuesday, April 09, 2013

Shanghai: Testing Reveals No Widespread H7N9 In Market Poultry

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Photo Credit – FAO

 

# 7099

 

 

A report this morning from Xinhua News reveals only a small percentage of Shanghai market birds tested this week showed signs of the newly emerging H7N9 virus.

 

Of 738 samples collected from  birds and surrounding environment, only 20 (less than 3%) proved positive for the H7N9 virus.

 

The type and sensitivity of these tests are not described in this report, nore are we provided with exactly how many birds were tested. We basically learn that only 10 chickens, and 3 pigeons tested positive.

 

 

No H7N9 epidemic among poultry: expert

 

English.news.cn   2013-04-09 15:32:06

BEIJING, April 9 (Xinhua) -- A preliminary analysis shows that H7N9 bird flu has not triggered an epidemic among poultry, according to a Tuesday report in the People's Daily that cited a veterinary expert.

 

Of the 738 samples collected from three live poultry markets in Shanghai, where the first known human deaths of the disease were reported, only 20 samples contained H7N9 virus, including 10 from chickens, three from pigeons and seven from environmental samples, the report said.

 

The government's chief veterinarian Yu Kangzhen was quoted as saying that it was the first time the Ministry of Agriculture had detected the virus in domestic animals.

 

The relationship between the virus detected in poultry and the virus that has infected humans has yet to be determined, Yu said.

 

The possibility of infection among animals in other regions has not been ruled out and the ministry has called for epidemic monitoring for animals across the nation, the report said.

 

It quoted Yu as saying that it's still safe to eat poultry meat purchased from regular channels, such as supermarkets, as long as they are thoroughly cooked.

 

"The virus could be killed under high temperature," said Yu.

 


While reassuring to poultry sellers in Shanghai, this report (if corroborated by additional testing in Shanghai and other provinces) leaves us without clear answers regarding the reservoir host (or hosts) for this virus, or the manner in which 24 people have recently been infected.

 

The epidemiological investigation continues.  Stay tuned.

Sunday, April 07, 2013

Shanghai: 2 Additional H7N9 Cases – Count Now At 20

image

Credit Wikipedia

 

 

# 7087

 

A statement this morning from Shanghai’s Municipal Health Bureau describing two new H7N9 cases, one from Shanghai and the other from neighboring Anhui Province.

 

The latest cases are described as:

 

Shen, age 59, M, Retiree, Onset March 25th

Lee, age 67, M, ? , Onset March 30th

 

These latest two cases raise the total number of confirmed H7N9 cases in China to 20. 

 

 

 

 

Shanghai new confirmed cases of human infection with the H7N9 avian influenza in two cases

As of today (7th) 17:00, the city newly diagnosed cases of human infection of H7N9 avian influenza. Up to now, Shanghai has found 10 cases of human infection of H7N9 avian influenza confirmed cases, including four cases of death, and the other six cases being treated in isolation.

 

2 new cases as follows:

 

Patients Shen, male, 59 years old, Anhui, retirees. Patients March 25, recurrent fever, cough, and themselves to a nearby pharmacy to buy medication, did not improve the patient to Tang town, Pudong New Area Community Health Center and Pudong New Area People's Hospital on March 30-April 1, has treatment. April 4, patients go to Yan Chai Hospital Pudong Branch of treatment, diagnosis of severe pneumonia, in being active treatment. On the evening of April 6, Shanghai Municipal Center for Disease Control laboratory test results for the H7N9 avian influenza virus nucleic acid positive. In accordance with the relevant requirements, the Shanghai Municipal Health and Family Planning Commission organized municipal clinical expert group to discuss the cases, experts based on the clinical manifestations, laboratory testing and epidemiological data, the diagnosis of the cases of human infection confirmed cases of the H7N9 avian flu . After investigation, the close contacts of cases total of four people, until now, were not unusual.

 

Patients Lee, male, 67 years old, the people of Shanghai. Patients March 29, body aches, fever, South hospital on March 30 to the First People's Hospital, the diagnosis of the upper left pneumonia. In the early morning of April 7, Shanghai Disease Prevention and Control Center laboratory test results for the H7N9 avian influenza virus nucleic acid positive. In accordance with the relevant requirements, the Shanghai Municipal Health and Family Planning Commission organized municipal clinical expert group to discuss the cases, experts based on the clinical manifestations, laboratory testing and epidemiological data, the diagnosis of the cases of human infection confirmed cases of the H7N9 avian flu . The patient's condition is stable and under active treatment. After investigation, the close contacts of the cases total of 2 people, until now, were not unusual.

 

As of this afternoon, the city had a total of 10 confirmed cases, 194 close contacts carried out under medical observation. All close contacts, accumulated a fever with cough or sore throat and other symptoms in close contact, 2 people in Shanghai Public Health Clinical Center, treatment, laboratory tests have been to exclude the H7N9 avian flu.

Saturday, April 06, 2013

Shanghai Health Bureau: Two New H7N9 Cases

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Credit Wikipedia

 

UPDATE:  Within an hour of this news breaking the World Health Organization  @WHO issued the following announcement on Twitter:

image

 

 


# 7086

 

My thanks to posts by Shiloh & Treyfish on FluTrackers  this morning (see thread) that led me to this press release from Shanghai’s Municipal Health Bureau  describing two new H7N9 cases diagnosed in Shanghai.

 

The patients are listed as:

 

Zhou, age 74, M, Farmer, Onset March 28th

Yang, age 66, M, Retiree, Onset March 29th

 

 

Shanghai new confirmed cases of human infection with the H7N9 avian influenza in two cases

 

As of today (April 6) 18:30 city newly diagnosed two cases of human infection with the H7N9 avian influenza. Until now, a total of eight cases of human infection with the H7N9 avian influenza confirmed cases, including four cases of death, the other four cases is where.

 

New cases are as follows:

 

Patients Zhou, male, 74 years old, the people of Shanghai, farming. Patients 28 March conscious weakness, shortness of breath, fever, March 31 to Fengxian District Chinese Medicine Hospital for treatment, transferred to East hospital on April 5, diagnosed with severe pneumonia, being active treatment. In the morning of April 6, the Shanghai Municipal Center for Disease Control laboratory test results for the H7N9 avian influenza virus nucleic acid positive. Organization municipal clinical expert in accordance with the relevant requirements, the Shanghai Municipal Health and Family Planning Commission to discuss the cases, the experts based on the clinical performance of laboratory testing and epidemiological data, the diagnosis of the cases of human infection of H7N9 avian influenza confirmed cases . After investigation, a total of five people in the close contacts of the cases, were not found until now an exception.

 

Patients Yang, male, 66 years old, the people of Shanghai, retirees. Patients chills symptoms on March 29, on April 2 to the Tenth People's Hospital for treatment, diagnosis of acute upper respiratory tract infection, given symptomatic treatment. April 4 patients symptoms were not relieved, and a cough, fever symptoms, once again to the Tenth People's Hospital for treatment, diagnosis of left lower pneumonia. In the morning of April 6, the Shanghai Municipal Center for Disease Control laboratory test results for the H7N9 avian influenza virus nucleic acid positive. Organization municipal clinical expert in accordance with the relevant requirements, the Shanghai Municipal Health and Family Planning Commission to discuss the cases, the experts based on the clinical performance of laboratory testing and epidemiological data, the diagnosis of the cases of human infection of H7N9 avian influenza confirmed cases . The patient's condition is stable and under active treatment. After investigation, the close contacts of the cases to a total of six people, until now, were not unusual.

 

 

This should increase the total to 18 cases, 6 fatal across four provinces in Eastern China.  

Thursday, April 04, 2013

Shanghai: Culling Begins While One Contact Shows Signs Of Illness

 

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Photo Credit – FAO

 

# 7074

 

 

The big news today coming out of China, beyond the five new cases and 2 deaths (see Xinhua: Updating The H7N9 Case Counts In Shanghai), has been the detection of the H7N9 virus in pigeons tested at a live-bird market.

 

We are also seeing reports that at least one contact of a confirmed (fatal) case has now developed symptoms, and is in isolation. 

 

Even though it is the middle of the night in China, reports and announcements continue to filter out  via Weibo, Twitter, and other media sources.

 

The following update (h/t Eric) from Xinhua News indicates that extensive culling of poultry has now been ordered. The mention of a `contact’ in isolation may be significant, as it is at least suggestive of H2H transmission, although we have no laboratory confirmation of infection. 

 

 

Shanghai begins culling poultry; one contact shows flu symptoms

English.news.cn   2013-04-05 01:30:22

SHANGHAI, April 5 (Xinhua) -- Authorities in Shanghai on Thursday closed a live poultry trading zone in an agricultural products market and began slaughtering all birds there after detecting H7N9 bird flu virus from samples of pigeon from the market.

 

Meanwhile, a person who had close contact with a dead H7N9 bird flu patient in Shanghai has been under treatment in quarantine after developing symptoms of fever, running nose and throat itching, the Shanghai Municipal Health and Family Planning Commission said late Thursday.

 

China's Ministry of Agriculture said Thursday it found the H7N9 virus from pigeon samples collected at the Huhuai wholesale agricultural products market in Songjiang district of Shanghai.

 

After gene sequence analysis, the national avian flu reference laboratory concluded that the strain of the H7N9 virus found on pigeons was highly congenetic with those found on persons infected with H7N9 virus, the ministry said.

 

The Shanghai municipal agricultural commission said it has ordered proper disposal of the culled birds, their excrements and contaminated food as well as disinfection of the market and vehicles that carried them and other things that have contacts with them.

 

The commission will also investigate and track where the pigeons came from, it said.

Meanwhile, the agency ordered the closure of the live poultry trading areas of two markets in Minhang district after samples there were found with H7 bird flu virus.

(Continue . . . )

 

 

You may recall that it was the controversial decision by Margaret Chan to cull all of the poultry in Hong Kong in 1997 that was credited with eventually stopping the first outbreak of H5N1 in its tracks. 

 

In that case, the H5N1 bird flu virus was more geographically contained. We currently have reports of H7N9 cases from multiple cities across three provinces, which will make culling operations more difficult.

 

It is unknown at this time where or how the pigeons that tested positive in the Shanghai market contracted the virus, or how many of the human infections are due to poultry exposure.

 

Whether this virus has found a home in the wild bird population, or other host animals (like pigs, rodents, or other small mammals) is likewise an open question.

 

Until the actual sources and modes of transmission of this virus are better understood, containment and eradication strategies such as culling may only prove partially successful.

Xinhua: Updating The H7N9 Case Counts In Shanghai

image

Credit Wikipedia

 

# 7073

 

 


The news on new and/or suspected infections with the emerging H7N9 virus continue to come in via a variety of sources, including Twitter, Weibo, and more traditional news sources.  


Sometimes these reports are fragmented, confusing, or difficult to decipher machine translations from Chinese.  While these translated reports are often useful, English language reports are generally more reliable.


Via Xinhua news, we get this most recent summary of cases, in English:

 

China has confirmed 14 H7N9 cases -- six in Shanghai, four in Jiangsu, three in Zhejiang and one in Anhui, in the first known human infections of the lesser-known strain. Of all, four died in Shanghai and one died in Zhejiang.

 

It seems likely that more cases will be identified over the coming days, but until we can learn the mode of transmission, it is impossible to say how much of a public health threat this virus currently poses.

 

Here is the Xinhua report in its entirety.

 

 

China reports 5th death from H7N9 bird flu

English.news.cn   2013-04-04 23:00:20
 

SHANGHAI, April 4 (Xinhua) -- Authorities in Shanghai said Thursday night that another person has died from H7N9 bird flu, bringing the death toll from the new deadly strain to five around the country.

 

The city has reported six infections to date, and four have died, said the Shanghai Municipal Health and Family Planning Commission.

 

Of the rest two, there was a four-year-old, the agency said. The baby was recovering from mild illness, it added.

 

The person died at Huashan Hospital on Wednesday and was confirmed infected with the H7N9 strain on Thursday. The commission gave no further information on the latest case.

 

Also on Thursday, the commission reported the city's third death from the H7N9 bird flu.

 

The case involved a 48-year-old man surnamed Chu, a poultry transporter from Rugao in neighboring Jiangsu Province.

 

He developed symptoms of cough on March 28. After having a fever on Monday, he went to a private clinic for treatment. The man then sought help in the Tongji Hospital in Shanghai in the early hours of Wednesday after his condition worsened.

 

Chu died three hours after being admitted to the hospital. He was confirmed infected with the H7N9 virus on Thursday. Eight people who had close contact with him have shown no abnormal symptoms.

 

So far, China has confirmed 14 H7N9 cases -- six in Shanghai, four in Jiangsu, three in Zhejiang and one in Anhui, in the first known human infections of the lesser-known strain. Of all, four died in Shanghai and one died in Zhejiang.

 

 

China's Ministry of Agriculture said Thursday the H7N9 avian flu virus has been detected from pigeon samples collected at a marketplace in Songjiang District of Shanghai.

 

After gene sequence analysis, the national avian flu reference laboratory concluded that the strain of the H7N9 virus found on pigeons was highly congenetic with those found on persons infected with H7N9 virus.

 

The ministry has ordered beefed-up monitoring of H7N9 bird flu virus in more areas.

 

China's health authorities have promised transparency and cooperation to the World Health Organization in regards to human infections of the new strain of bird flu.

 

The Chinese Center for Disease Control and Prevention said Wednesday that no human-to-human transmission of H7N9 has been discovered and no epidemiological connection between these cases has been found.