Showing posts with label Statement. Show all posts
Showing posts with label Statement. Show all posts

Monday, April 20, 2015

WHO Statement On Ebola Response & Needed Reforms

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Credit CDC PHIL

 

# 9958

 

Overnight the World Health Organization published – and sent out to journalists – a statement on this past year’s Ebola response in Western Africa, the lessons learned, and the changes that must be made to ensure a better response the next time a major disease outbreak occurs.

 

 

WHO leadership statement on the Ebola response and WHO reforms

16 April 2015

The Ebola outbreak that started in December 2013 became a public health, humanitarian and socioeconomic crisis with a devastating impact on families, communities and affected countries. It also served as a reminder that the world, including WHO, is ill-prepared for a large and sustained disease outbreak.

We, the Director-General, Deputy Director-General, and Regional Directors of WHO, are making this commitment of collective leadership to Member States and their peoples in line with recommendations made by the Special Session of the Executive Board on Ebola held in January 2015. We have taken note of the constructive criticisms of WHO’s performance and the lessons learned to ensure that WHO plays its rightful place in disease outbreaks, humanitarian emergencies and in global health security.

What have we learned?

We have learned that new diseases and old diseases in new contexts must be treated with humility and an ability to respond quickly to surprises. Greater surge capacity contributes to a flexible response.

We have learned lessons of fragility. We have seen that health gains – fewer child deaths, malaria coming under control, more women surviving child birth – are all too easily reversed, when built on fragile health systems, which are quickly overwhelmed and collapse in the face of an outbreak of this nature.

We have learned the importance of capacity. We can mount a highly effective response to small and medium-sized outbreaks, but when faced with an emergency of this scale, our current capacities and systems – national and international – simply have not coped.

We have learned lessons of community and culture. A significant obstacle to an effective response has been the inadequate engagement with affected communities and families. This is not simply about getting the right messages across; we must learn to listen if we want to be heard. We have learned the importance of respect for culture in promoting safe and respectful funeral and burial practices. Empowering communities must be an action, not a cliché.

We have learned lessons of solidarity. In a disease outbreak, all are at risk. We have learned that the global surveillance and response system is only as strong as its weakest links, and in an increasingly globalized world, a disease threat in one country is a threat to us all. Shared vulnerability means shared responsibility and therefore requires sharing of resources, and sharing of information.

We have learned the challenges of coordination. We have learnt to recognise the strengths of others, and the need to work in partnership when we do not have the capacity ourselves.

We have been reminded that market-based systems do not deliver on commodities for neglected diseases – endemic nor epidemic. Incentives are needed to encourage the development of new medical products for diseases that disproportionately affect the poor. The scientific community, the pharmaceutical industry, and regulators have come together in a collaborative effort to vastly compress the time needed to develop and approve Ebola vaccines, medicines, and rapid diagnostic tests. In future, this ad hoc emergency effort needs to be replaced by more routine procedures that are part of preparedness.

Finally, we have learned the importance of communication – of communicating risks early, of communicating more clearly what is needed, and of involving communities and their leaders in the messaging.

What must we do?

We will engage with national authorities and request them to keep outbreak prevention, preparedness and response management at the top of national and global agendas.

We will develop the capacity to respond rapidly and effectively to disease outbreaks and humanitarian emergencies. This will require a directing and coordinating mechanism to bring together the world’s resources to mount a rapid and effective response. We commit to expanding our core staff working on diseases with outbreak potential and health emergencies so we will have skilled staff always available at the three levels of WHO. We will also create surge capacity of teams of trained and certified staff so that we have a reserve force in the event of an emergency.

We will create a Global Health Emergency Workforce – combining the expertise of public health scientists, the clinical skills of doctors, nurses and other health workers, the management skills of logisticians and project managers, and the skills of social scientists, communication experts and community workers. This Global Health Emergency Workforce will be made up of teams of trained and certified responders who can be available immediately. A key principle must be to build capacity in countries, with training and simulation exercises.

We will establish a Contingency Fund to enable WHO to respond more rapidly to disease outbreaks. We must ensure adequate resources – domestic and international - are available before the next outbreak.

We recognize that emergency situations demand a command and control approach and we commit to seamless collaboration between headquarters, regional offices, and country offices. Better WHO systems for rapid staff deployments, data collection and reporting, expansion of laboratory services, logistics, and coordination were developed as the outbreak evolved. These systems will be institutionalized.

The massive international response revealed the unique strengths of multiple partners, including UN agencies. We will build on these partnerships, concentrating on capacities that are most critically needed under the demanding conditions of emergencies.

We will strengthen the International Health Regulations – the international framework for preparedness, surveillance and response for disease outbreaks and other health threats. We commit to strengthening our capacity to assess, plan and implement preparedness and surveillance measures. We will scale up our support to countries to develop the minimum core capacities to implement the IHR. We will establish mechanisms for independent verification of national capacity to detect and respond to disease threats.

We will develop expertise in community engagement in outbreak preparedness and response. We will emphasise the importance of community systems strengthening and work with partners to develop multidisciplinary approaches to community engagement , informed by anthropology and other social sciences.

We will communicate better. We commit to provide timely information on disease outbreaks and other health emergencies as they occur. We will strengthen our capacity for outbreak and risk communications.

We call on world leaders to take the following steps

First, take disease threats seriously. We do not know when the next major outbreak will come or what will cause it. But history tells us it will come. This means investing domestically and internationally in prevention and in essential public health systems for preparedness, surveillance and response, which are fully integrated and aligned with efforts to strengthen health systems, and included in the scope of development assistance for health.

Second, remain vigilant. This Ebola outbreak is far from over, and we must sustain our support to the affected countries until the outbreak is over, in the face of increasing complacency and growing fatigue. We must continue to maintain a high level of surveillance. Ebola has demonstrated its capacity to spread – it may do so again.

Third, engage to re-establish the services, systems and infrastructure which have been devastated in Guinea, Liberia and Sierra Leone. This recovery must be country-led, community-based, and inclusive – engaging the many partners who have something to contribute; including bilateral and multilateral partners, national and international NGOs, the faith community, and the private sector.

Fourth, be transparent in reporting. Accurate and timely information is the basis for effective action. Speedy detection facilitates speedy response and prevents escalation.

Fifth, invest in research and development for the neglected diseases with outbreak potential – diagnostics, drugs, and vaccines. This will require innovative financing mechanisms, and public-private partnerships.

This is our commitment; together we will ensure that WHO is reformed and well positioned to play its rightful role in disease outbreaks, humanitarian emergencies and in global health security.

Thursday, April 09, 2015

CDC Statement On Canine Influenza In Chicago

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3D model generic Flu Virus – Credit CDC PHIL

 

# 9920

 

 

Up until a dozen years ago, most veterinarians would have told you that dogs are not generally susceptible to influenza viruses, but that notion changed in 2004 when we saw the jump of equine H3N8-like influenza to Florida greyhounds.

 

In 2008, an EID Journal article reported:

 

Influenza A Virus (H3N8) in Dogs with Respiratory Disease, Florida

Sunchai Payungporn*, P. Cynda Crawford†, Theodore S. Kouo*, Li-mei Chen*, Justine Pompey*, William L. Castleman†, Edward J. Dubovi‡, Jacqueline M. Katz*, and Ruben O. Donis*Comments to Author
Abstract

In 2004, canine influenza virus subtype H3N8 emerged in greyhounds in the United States. Subsequent serologic evidence indicated virus circulation in dog breeds other than greyhounds, but the virus had not been isolated from affected animals. In 2005, we conducted virologic investigation of 7 nongreyhound dogs that died from respiratory disease in Florida and isolated influenza subtype H3N8 virus.

Antigenic and genetic analysis of A/canine/Jacksonville/2005 (H3N8) and A/canine/Miami/2005 (H3N8) found similarity to earlier isolates from greyhounds, which indicates that canine influenza viruses are not restricted to greyhounds. The hemagglutinin contained 5 conserved amino acid differences that distinguish canine from equine lineages. The antigenic homogeneity of the canine viruses suggests that measurable antigenic drift has not yet occurred. Continued surveillance and antigenic analyses should monitor possible emergence of antigenic variants of canine influenza virus.

 


Like its equine counterpart (which has been around at least a half century) - canine H3N8 has not been shown to infect humans. The CDC considers this a dog-specific lineage of H3N8.

 

North American canine H3N8 should not be confused with a similarly named avian Mammalian Adapted H3N8 In Seals, Equine H3N8, or the more recently emerged canine H3N2 virus which is spreading in dogs and cats across parts of Asia (see Korea: Interspecies Transmission of Canine H3N2).

 

Over the past few weeks there has been an unusually large outbreak of canine H3N8 in and around the Chicago area, and yesterday the CDC posted the following statement.

 

Canine Influenza (Dog Flu) Outbreak in Chicago Area

April 8, 2015 – CDC is aware of reports of a canine influenza (dog flu) outbreak in the Chicago area. Dog flu is a contagious respiratory disease in dogs that does not cause illness in humans. A vaccine against this disease in dogs has been available since 2009. CDC recommends that people concerned about dog flu speak to their veterinarian.

Signs of dog flu infection include cough, runny nose and fever, but not all dogs will exhibit signs. The severity of illness associated with dog flu can range from no signs to severe illness resulting in pneumonia and sometimes death. Tests are available to determine if a dog has been infected, and your veterinarian can tell you if testing is appropriate. You and your veterinarian can also discuss whether vaccinating your dog against canine influenza is indicated.

Dog flu is caused by an influenza A (H3N8) virus that is closely related to an influenza virus found in horses for over 40 years. Experts believe this horse influenza virus changed in a way that allowed it to infect dogs, and the first dog flu infections caused by these viruses were reported in 2004, initially in greyhounds. This virus is now considered a dog-specific lineage of influenza A (H3N8) virus. Almost all dogs can be susceptible to infection, and illness tends to spread among dogs housed in kennels and shelters.

To date, there is no evidence of transmission of dog flu from dogs to people and there has not been a single reported case of human infection with the canine influenza virus.

For more information on dog flu, please visit:



While this strain of canine influenza is not currently viewed as having zoonotic properties, we’ve looked at studies on other canine-acquired influenza viruses – particularly in Asia – that have put dogs on the radar as a possible `mixing vessel’ for influenza reassortment.

 

A few recent blogs include:

 

Virology J: Human-like H3N2 Influenza Viruses In Dogs - Guangxi, China

China: Avian-Origin Canine H3N2 Prevalence In Farmed Dogs

MAFRA: H5N8 Antibodies Detected In South Korean Dogs (Again)

Wednesday, March 25, 2015

Saudi MOH: Fines And/Or Prison For Failure To Report MERS Cases

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Saudi Arabia

 

# 9862

 

Although it boggles the mind that this should be an ongoing problem, apparently the Saudi MOH is concerned that health practitioners are still not reporting all MERS cases to the Ministry of Health – essentially covering up cases.  

 

Last month it was widely reported in the Saudi press that Hospitals that do not report MERS cases would be shut down, with the the ministry undersecretary for general health warning:

“Fines of up to SR100,000 will be imposed on the facilities and on health practitioners who conceal cases, do not report them or do not take the necessary measures to prevent the spread of the disease.- Abdul Aziz Bin Saeed

 

Now, based on a statement posted today on the Saudi MOH website, a prison term of up to 6 months can be tacked on for failure to report as well.

 

Prison and a fine b (100) thousand riyals for not reporting injuries (Corona)

05 June 1436

From the keenness of the Ministry of Health to improve the work in health facilities, and to ensure the reduction of the spread of the virus (Corona) that causes respiratory syndrome, the Middle East, The ministry has stressed the need for the health practitioner's commitment to including issues of the decisions and instructions governing the reporting of infectious diseases, and are reported to the competent authorities, directly or through an entity that owns the health practitioner, including virus (Corona).

And the Minister of Health in the mainstream with his face to the directorates of health affairs in all regions of the Kingdom, the ministry emphasizes the paramount importance of reporting suspected syndrome Middle East respiratory (Corona) through the system adopted (fort); because the status quo is actively infectious diseases associated with, including Syndrome Middle East respiratory (Corona), requires all health practitioners to take maximum vigilance and readiness degrees.

Circular also stressed that the lack of communication or delay in reporting cases presents health practitioner violator to criminal responsibility and punishment prescribed in the system, and that link to jail for a period not exceeding six months and a fine of not more than 100 thousand riyals, or one of the two penalties, disciplinary sanctions the other, in addition to the consequent penalties of up to revocation of the license to practice the profession and write off the name of the licensed record.

 

While trying to hide cases may seem like absolute folly, it isn’t difficult to envision cases where the temptation may exist.

 

  • Hospitals or clinics that report nosocomial infections are subject to additional scrutiny by the MOH, including a review of their infection control protocols, which if found wanting could result in fines or other punitive actions (in extreme cases, even closure – see Saudi MOH Closes Riyadh Dialysis Center Over MERS Concerns).
  • Hospitals or clinics that admit to having MERS cases are likely to see a decrease in patient census, or difficulties keeping staff, over MERS concerns
  • And wealthy or powerful patients may offer `incentives’ to practitioners to avoid the stigma of being labeled a `MERS’ case.

 

Just how big a problem this really is in Saudi Arabia is hard to say, but the MOH has been ratcheting up MERS reporting and infection control warnings to healthcare facilities since early last fall.

Saturday, February 07, 2015

Saudi MOH Statement On MERS

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# 9683

 

 

Likely in response to both the recent surge in MERS cases, and media reports accusing the MOH of `secrecy’, the Saudi Ministry of Health has today published the following (translated) statement, confirming 11 MERS cases since the first of the month, and reminding people to practice good hygiene and to avoid close contact with camels. 

 

Ministry News

Health: Register (11) cases of Corona virus since the beginning of February

18 April 1436

In the framework of transparency adopted by the Ministry of Health and a continuation of the epidemiological surveillance carried out by the desire to keep everyone on the latest developments regarding the Corona virus that causes AIDS Middle East respiratory, the ministry would like to take it still recorded sporadic cases infected with the virus in some areas of the UK where the ministry recorded (11 ) case since the beginning of the month of February (2), two of them in Hofuf and (1) one case in Dammam and (2) two cases in output and five (5) cases in Riyadh and (1) one case in Najran and all of these cases gained outside hospitals where it is expected due to the change in the atmosphere during the coming period to increase the number of cases of respiratory infections, including HIV Corona, the ministry continues in collaboration with the Ministry of Agriculture and the World Health Organization WHO and the Center for Disease Control and American control of CDC and other stakeholders related to the application of precautionary and preventive measures to deal with the virus through a command and control center of the Ministry of Health to maintain the health and safety of all members of society, God willing.

The ministry stressed the importance of prevention of infection and advised citizens and residents of the following practices which wash your hands with soap and water and avoid contact with sick and refrain from touching the eyes, nose and cough into a tissue or put the arm on the mouth and then wash your hands as well as the arm carefully and avoid dealing in close contact with infected camels respiratory symptoms and commitment preventive measures when dealing with camels. Everyone must especially for those who have chronic illnesses to avoid contact with camel milk is boiled or eating or scalded with the importance of maintaining good health habits in general.

The ministry called on all workers in health facilities comply with the instructions and the application of preventive measures and work the basics of infection control and compliance paths sort of respiratory cases in emergency departments and the use of personal protective tools according to the instructions notifying them of the command and control center at the Ministry of Health.

And called on everyone if you want to get more information and to identify the steps infection prevention visit the ministry's website Www.moh.gov.sa   . It should be noted that the total number of cases of infection with Corona, which is currently under treatment in hospitals amounted to gross (15) case, including cases where the (11) recorded since the beginning of the current calendar month, we ask God for their healing and wellness.

 

With a new Health Minister - Dr. Muhammad Bin Ali Al-Hayazie – recently appointed, and a cloud of suspicion (see MOH Cancels Coronavirus Contracts Over Corruption Allegations) over previous Ministry management of MERS,  Saudi Arabia faces some unique challenges as this year’s `MERS season’ (March through May) approaches. 

The figure is an epidemiologic curve showing the number of cases of Middle East respiratory syndrome (MERS) coronavirus infection reported by the World Health Organization, by month and year of illness onset, worldwide during 2012-2015. The majority (504) of the 956 MERS cases were reported to have occurred during March-May 2014.

CDC MMWR - Number of cases of MERS infections reported by the World Health Organization,* by month of illness onset — worldwide, 2012–2015

 


Complicating matter, a recent EID Journal Dispatch (Lack of Middle East Respiratory Syndrome Coronavirus Transmission from Infected Camels) has been frequently misinterpreted, and heralded in the Arabic media (and via social media) as `exonerating beauty’ in the transmission of MERS.


This EID dispatch, which only looked at transmission to humans from one camel herd over a 90 day period,  specifically stated:

 

Our findings do not imply that dromedaries are not a source of infection for humans. Spillover infection of humans may be more common in other settings in which humans are exposed over sustained periods to animals among which virus prevalence is higher.

But that part of the story has either been ignored, or minimized, in the Arabic press.

 

The real takeaway is that camel to human transmission is rare, but it is a likely conduit of the virus into the human population.  Once seeded, humans continue to spread the virus (albeit, only with limited efficiency) to others. 

 

The R0, or basic reproduction number of the virus, remains low enough (< 1.0)  that the disease hasn’t taken off in humans yet. 

 

But as long as these rare camel-to-human zoonotic transmissions keep happening, new chains of human transmission will likely emerge.  And that gives the virus additional opportunities to acquire host adaptations that may eventually increase its threat to mankind.

Wednesday, December 24, 2014

CDC Statement On Ebola Lab Incident

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Credit CDC PHIL

 


# 9486

 

I’ve finally located the CDC’s statement on the Ebola lab incident (see CDC Reports Potential Ebola Exposure At Lab) announced late this afternoon.

 

Lab Safety Report on Ebola Virus Transfer


The Centers for Disease Control and Prevention is reporting today that a small amount of material from an Ebola virus experiment that was securely transported from a Select-Agent-approved BSL-4 lab to a Select-Agent-approved BSL-2 lab may have contained live virus. The material was on a sealed plate but should not have been moved into the BSL-2 laboratory. We cannot rule out possible exposure of the one laboratory technician who worked with the material in the BSL-2 laboratory.


There was no possible exposure outside the secure laboratory at CDC and no exposure or risk to the public. The event was discovered by the laboratory scientists yesterday, December 23, and reported to leadership within an hour of the discovery.


The event is under internal investigation by CDC, was reported to Secretary of Health and Human Services Sylvia Burwell, and reporting to the internal and national Select Agent Programs has been initiated. CDC will provide a report on the event when the investigation concludes. The BSL-2 laboratory area had already been decontaminated and the material destroyed as a routine procedure before the error was identified. The laboratory was decontaminated for a second time, and is now closed and transfers from the BSL-4 lab have been stopped while the review is taking place.


"I am troubled by this incident in our Ebola research laboratory in Atlanta," said CDC Director Tom Frieden, M.D., M.P.H. "We are monitoring the health of one technician who could possibly have been exposed and I have directed that there be a full review of every aspect of the incident and that CDC take all necessary measures. Thousands of laboratory scientists in more than 150 labs throughout CDC have taken extraordinary steps in recent months to improve safety. No risk to staff is acceptable, and our efforts to improve lab safety are essential -- the safety of our employees is our highest priority."


CDC will continue to provide support during the Ebola epidemic through its research and diagnostic lab work. Skilled lab scientists in the Ebola response are valued contributors to ending this epidemic.

Based on what was learned during the lab science and safety reviews earlier this year, CDC has taken several immediate actions in this incident including closure of the laboratory, notification of staff, initiation of a complete internal review, and notifications of regulatory oversight agencies. This review will give us a clear understanding of what happened in this case and what can be done to further improve laboratory safety.

CDC has established a CDC-wide single point of accountability for laboratory science and safety and this will aid in ensuring accountability in this situation. CDC will also report this event to its external advisory committee which provides ongoing advice and direction for laboratory science and safety.


One person--the BSL-2 lab technician who processed the material and who currently has no symptoms of illness--has been assessed and will be monitored for 21 days, according to CDC guidance. Others who entered the lab have been contacted and were assessed for possible exposure. As of this time we believe exposure requiring monitoring is limited to one individual.

 

Friday, October 24, 2014

CDC Statement: Ebola Case Tests Positive In NYC

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Credit CDC PHIL

 

 

# 9242

 

A not altogether unexpected statement this evening, given the media reports of this Healthcare Workers symptoms and recent work in Ebola stricken Guinea, but this evening the CDC has announced that local testing indicates he has been infected with the Ebola virus.

 

Confirmatory testing should come from the CDC in the coming hours, but there seems little doubt in the matter.


The epidemiological investigation is already underway, and potential contacts of this patient will be identified, notified, and monitored for up to 21 days. The good news is, Ebola patients are believed to be less infectious during the early hours and days of showing symptoms.



While many were hopeful as we approached the end of the 21 day incubation period in Dallas without any more cases, this is a reminder that as long as the virus is spreading in West Africa, the rest of the world is at risk from new importations of the virus.

 

I expect we will get a good many more details in the coming hours.  In the meantime we have the following statement from the CDC’s press room.

 

New York City Reports Positive Test for Ebola in Volunteer International Aid Work

A hospitalized medical aid worker who volunteered in Guinea, one of the three West African nations experiencing an Ebola epidemic, and since returned to the United States has tested positive for Ebola according to the New York City Health Department laboratory, which is part of the Laboratory Response Network overseen by the Centers for Disease Control and Prevention.

The patient has been notified of the test results and remains in isolation. The patient is currently at Bellevue Hospital in New York City. Bellevue Hospital is one of eight New York State hospitals that Governor Cuomo has designated to treat Ebola patients. A specially trained CDC team determined earlier this week that the hospital has been trained in proper protocols and is well prepared to treat Ebola patients.

Confirmation testing at the Centers for Disease Control and Prevention's laboratory will be done. The healthcare worker had returned through JFK Airport on Oct. 17 and participated in the enhanced screening for all returning travelers from these countries. He went through multiple layers of screening and did not have a fever or other symptoms of illness. The patient reported a fever to local health officials for the first time today. The patient was transported by a specially trained HAZ TAC unit wearing Personal Protective Equipment (PPE) to Bellevue. The New York City Health Department has interviewed the patient regarding close contacts and activities.

CDC is in close communications with the New York City Health Department and Bellevue Hospital, and is providing technical assistance and resources. Three members of CDC's Ebola Response Team will arrive in New York City tonight. This team is deployed when an Ebola case is identified in the United States, or when health officials have a very strong suspicion that a patient has Ebola pending lab results.

In addition, CDC already had a team of Ebola experts in New York City who can offer immediate additional support. The CDC experts were in New York City this week assessing hospital readiness to receive Ebola patients, including Bellevue hospital. CDC's Ebola hospital assessment teams are designed to make sure that hospitals that have volunteered to take Ebola patients are Ebola ready.

These teams assess a facility's infection control readiness and to determine if there are gaps in infection control readiness. They support a facility in developing a comprehensive infection control plan. The principle is to be ready for the patient coming in the front door and everything that happens through the patient's stay in the hospital. CDC's team is a multidisciplinary team of experts. It includes infection control practice specialists, personal protective equipment specialists, worker safety experts, clinical care and diagnostics experts, and laboratory processes experts. New York City and New York State have designated Bellevue as an Ebola treatment hospital. The CDC team, which had completed its assessment of Bellevue, found the facility to be well prepared to care for a patient with Ebola.

Ebola is spread through direct contact with bodily fluids of a sick person or exposure to objects such as needles that have been contaminated. The illness has an average 8-10 day incubation period (although it could be from 2 to 21 days). CDC recommends monitoring exposed people for symptoms a complete 21 days.

Confirmatory CDC laboratory tests will be shared when these tests are done, following appropriate patient notification.

Thursday, October 16, 2014

Two Overnight Statements From Texas Health Presbyterian Hospital

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# 9202

 

The Dallas Hospital where America’s index case of Ebola died, and where at least two nurses were infected, has issued a pair of statements overnight.  

 

The first is an offer to employees who have had a potential exposure to the Ebola virus that they can self quarantine at the hospital. The second refutes a number of the claims lodged yesterday by local nurses regarding the infection control protocol used in the treatment of their index case (see Nurses Claim Lack Of Safety Protocols For Dealing With Ebola).

 

Ebola Update, Oct. 15, 9:44 p.m. CDT
10/15/2014

Ebola Virus

Statement from Texas Health Presbyterian Hospital Dallas

With a second one of our health care workers now infected with the Ebola virus despite following recommended protection procedures, Texas Health Dallas is offering a room to any of our impacted employees who would like to stay here to avoid even the remote possibility of any potential exposure to family, friends and the broader public.

We are doing this for our employees’ peace of mind and comfort.

This is not a medical recommendation. We will make available to our employees who treated Mr. Duncan a room in a separate part of the hospital throughout their monitoring period.

We want to remind potentially affected employees that they are not contagious unless and until they demonstrate any symptoms, yet we understand this is a frightening situation for them and their families. We will be coordinating this effort with the county monitors who are already regularly checking on their temperatures for any sign of infection.

The hospital will contact directly those being monitored to make arrangements. We also ask our potentially affected employees to be the good citizens that we know they are by avoiding using public transportation or engaging in any activities that could potentially put others at risk.

 

With regard to the charges made yesterday by the coalition of nurses, and the denials today by the hospital, I can only hope that a full and open hearing of the facts will be held, so that we can find out what actually happened.

Ebola Update, Oct. 16, 4:00 a.m. CDT
10/16/2014

Correcting the Record: Facts about Protocols and Equipment at Texas Health Presbyterian Hospital Dallas

National Nurses United recently made allegations regarding the protocols and equipment in place during Thomas Eric Duncan’s treatment at Texas Health Presbyterian Hospital Dallas.

The assertions do not reflect actual facts learned from the medical record and interactions with clinical caregivers. Our hospital followed the Centers for Disease Control (CDC) guidelines and sought additional guidance and clarity.

The following are facts about procedures and protocols in place during Mr. Duncan’s treatment:

  • When Mr. Duncan returned to the Emergency Department (ED), he arrived via EMS. He was moved directly to a private room and placed in isolation. THD staff wore the appropriate personal protective equipment (PPE) as recommended by the CDC at the time.
  • Regarding the ED tube delivery system utilized during Mr. Duncan’s initial visit, all specimens were placed into closed specimens bags and placed inside a plastic carrier that travel through a pneumatic system. At no time did Mr. Duncan’s specimens leak or spill — either from their bag or their carrier — into the tube system.
  • During Mr. Duncan’s second visit, the tube system was not used at all. His specimens were triple-bagged, placed in a container, and placed into a closed transport container and hand-carried to the lab utilizing the buddy system. Additionally, while Mr. Duncan was in the MICU, all lab specimens were hand-carried and sealed per protocol. Routine labs were done in his room via wireless equipment.
  • Nurses who interacted with Mr. Duncan wore PPE consistent with the CDC guidelines. Staff had shoe covers, face shields were required, and an N-95 mask was optional — again, consistent with the CDC guidelines at the time.
  • When the CDC issued updates, as they did with leg covers, we followed their guidelines.
  • When the CDC recommended that nurses wear isolation suits, the nurses raised questions and concerns about the fact that the skin on their neck was exposed. The CDC recommended that they pinch and tape the necks of the gown. Because our nurses continued to be concerned, particularly about removing the tape, we ordered hoods.
  • Protective gear followed governing CDC guidelines at the time.
  • The CDC classified risk/exposure levels. Nurses who were classified as “no known exposure” or “no risk” were allowed to treat other patients per the CDC guidance.
  • Per the CDC guidelines, patients who may have been exposed were always housed or isolated per the CDC guidance.
  • Regarding hazardous waste, the hospital went above and beyond the CDC recommendations. Waste was well-contained in accordance with standards, and it was located in safe and containable locations.
  • Admittedly, when we received Tyvek suits, some were too large. We have since received smaller sizes, but it is possible that nurses used tape to cinch the suits for a better fit.

According to an employee satisfaction survey by Press Ganey, Texas Health Dallas is in the top one percent in the country when it comes to employee engagement and partnership. We support the tireless and selfless dedication of our nurses and physicians, and we hope these facts clarify inaccuracies recently reported in the media.

Wednesday, October 08, 2014

WHO: Statement On The Risks Of Ebola `Spreading’ In Europe

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Credit CDC PHIL

 

# 9160

 


Sometimes, it is just easier to wait for the clarification that you know will be coming, than to blog a hyperbolic news story when it first appears. 

 

On Tuesday headlines screamed - More cases of Ebola spreading in Europe 'unavoidable', WHO says - after comments by Zsuzsanna Jakab, Regional Director of the European Region of the World Health Organization, were carried by the wire services.

 

Although Director Jakab added the continent should be well prepared to control any outbreaks that might occur, that wasn’t the thrust for the headlines that followed, which included:

 

Ebola will spread across Europe, warns WHO chief Zsuzsanna Jakab

Ebola unavoidable in Europe, says WHO as Spain rushes to contain case

 

Of course, it is likely inevitable that additional cases will present in Europe, North America, and around the world.  But the risks of it `spreading across Europe’ – as suggested by these headlines – are currently very low.


Today the World Health Organization emailed out the following statement:

 

Statement by Zsuzsanna Jakab, WHO Regional Director for Europe

Risk of Ebola spreading in Europe is very low

Sporadic cases of Ebola virus disease in Europe are unavoidable. This is due to travel between Europe and affected countries.

  
However, the risk of spread of Ebola in Europe is avoidable and extremely low. European countries are among the best prepared in the world to respond to viral haemorrhagic fever (VHF) including Ebola.


There is a risk of accidental contamination for people exposed to Ebola patients: this risk can be and must be mitigated with strict infection control measures. Health care workers are on the frontline of the Ebola fight and they are those most at risk of infection. They need to be protected and supported by all means.


All countries have protocols and procedures that must be implemented when a case is suspected and it is important that these are followed diligently. WHO is, as always, ready to provide help and support where requested.

Friday, October 03, 2014

Statement From The UN Mission For Ebola Emergency Response Regarding Transmission Of Ebola

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Credit WHO

 

# 9145

 

In a sane world, an official could at least raise the possibility of low probability-high impact event without it being blown all out of proportion by the press, the internet, and through osmosis -  the public. 

 

But measured, rational discussions don’t sell papers, drive web traffic, or grab cable news viewers. 

 

And so any acknowledgement of an infinitesimal risk – such as an asteroid strike,  a Yellowstone eruption, or `airborne Ebola-  becomes instant fodder for the media and pure manna for conspiratorialists worldwide.

 

Exhibit A – yesterday’s headlines (see Ebola 'could become airborne' in nightmare scenario, UN mission chief warns).

 

This,  is why we can’t have adult discussions anymore.  At least not in public.

 

Admittedly, Banbury should have known better than to go there. He had to have known how this would have been played in the press, and he (hopefully) knows just how low the risk of that sort of outcome really is. Not zero, but pretty darn close.

 

Yes, in a rational universe, we should be able to discuss all possibilities – no matter how remote.

 

But we don’t live in one of those.   So officials have to watch what they say very carefully.  Too carefully, in my opinion.  

 

Today the UN Mission for Ebola Emergency Response has issued the following clarification.

 

UN Mission for Ebola Emergency Response statement for clarification: No threat that Ebola is airborne 

ACCRA, GHANA, 3 October 2014

Following recent media reports, the UN Mission for Ebola Emergency Response (UNMEER) seeks to clarify that Ebola is not an airborne disease. At this point in time we have no evidence and do not anticipate that the Ebola virus is mutating to become airborne.


However, there are real risks and concerns with this outbreak: every day more people are becoming infected and more are dying because they cannot get the care they need. Energy needs to be focused on swiftly addressing the real needs and gaps in communities affected by this disease.


The Ebola virus only spreads through contact with bodily fluids. The World Health Organization (WHO) monitors the virus closely. Viruses do mutate but it is a complex process that takes time. Right now, as advised by WHO, the safest thing anyone can do is avoid direct contact with bodily fluids of people who have Ebola, and with surfaces and materials (e.g. bedding, clothing) contaminated with fluids.


Media contacts:
Currently with the UNMEER delegation in Sierra Leone
Christy Feig,
feigc@who.int, +41.79.251.7055
Jon Greenway,
greenway@un.org, +1.917.209.3956
Margaret Harris,
mharrisenator@gmail.com, harrism@who.int, (use both emails when sending a request),  +232 78 335 660

Friday, September 05, 2014

WHO Statement: Consultation On Potential Use of Ebola Therapies & Vaccines

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# 9044

 

The WHO press conference is still ongoing, but the World Health Organization has emailed out a statement (see below) that summarizes the findings of the two-day consultation on the use of experimental Ebola drugs and vaccines.


Audio files on the press conference (and later video) should be available later this afternoon at

http://www.who.int/mediacentre/en/

 

For now, the most immediately available experimental therapy – at least in some facilities capable of doing it safely -  is the use of convalescent serum harvested from recovered patients.  I discussed some of the technical details of this type of treatment yesterday, in a preview called WHO Consultation On Potential Ebola Treatments & Vaccines.


Safety, but not efficacy data on the two vaccines under development should be available by November.  Assuming that small-scale study goes well, experimental vaccines could be offered to a limited number of health care workers in a matter of months.

 

 

Statement on the WHO Consultation on potential Ebola therapies and vaccines

5 September 2014

After two days of discussion on potential Ebola therapies and vaccines, more than 150 participants, representing the fields of research and clinical investigation, ethics, legal, regulatory, financing, and data collection, identified several therapeutic and vaccine interventions that should be the focus of priority clinical evaluation at this time.


Currently, none of these vaccines or therapies have been approved for human use to prevent or treat EVD. A number of candidate vaccines and therapies have been developed and tested in animal models and some have demonstrated promising results. In view of the urgency of these outbreaks, the international community is mobilizing to find ways to accelerate the evaluation and use of these compounds.


Safety in humans is also unknown, raising the possibility of adverse side effects when administered. Use of some of these products is demanding and requires intravenous administration and infrastructure, such as cold chain, and facilities able to offer a good and safe standard of care.


The experts determined:

  • There was consensus that the use of whole blood therapies and convalescent blood serums needs to be considered as a matter of priority.
  • Safety studies of the two most advanced vaccines identified – based on vesicular stomatitis virus (VSV-EBO) and chimpanzee adenovirus (ChAd-EBO) – are being initiated in the United States of America and will be started in Africa and Europe in mid-September. WHO will work with all the relevant stakeholders to accelerate their development and safe use in affected countries. If proven safe, a vaccine could be available in November 2014 for priority use in health-care workers.
  • In addition to blood therapies and candidate vaccines, the participants discussed the availability and evidence supporting the use of novel therapeutic drugs, including monoclonal antibodies, RNA-based drugs, and small antiviral molecules. They also considered the potential use of existing drugs approved for other diseases and conditions. Of the novel products discussed, some have shown great promise in monkey models and have been used in a few Ebola patients (although, in too few cases to permit any conclusion about efficacy).


Existing supplies of all experimental medicines are limited. While many efforts are underway to accelerate production, supplies will not be sufficient for several months to come. The prospects of having augmented supplies of vaccines rapidly look slightly better.


The participants cautioned that investigation of these interventions should not detract attention from the implementation of effective clinical care, rigorous infection prevention and control, careful contact tracing and follow-up, effective risk communication, and social mobilization, all of which are crucial for ending these outbreaks.


The recipients of experimental interventions, location of studies, and study design, should be based on the aim to learn as much as we can as fast as we can without compromising patient care or health worker safety.


The recipients of experimental interventions, locations of studies, and study design should be based on the aim to learn as much as we can as fast as we can without compromising patient care or health worker safety, with active participation of local scientists, and proper consultation with communities.


This will require the following crucial elements:

  • Appropriate protocols must be rapidly developed for informed consent and safe use.
  • A mechanism for evaluating pre-clinical data should be put in place in order to recommend which interventions should be evaluated as a first priority.
  • A platform must be established for transparent, real-time collection and sharing of data.
  • A safety monitoring board needs to be established to evaluate the data from all interventions.

All of these will require continued ethical oversight.

Thursday, July 31, 2014

CDC Statement On Travel Warnings & Ebola Situation In West Africa

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Credit CDC Ebola Outbreak Website

 

# 8900

 

In concert with today’s press conference, and travel warnings, the CDC has released the following statement on the Ebola situation – and their response – in Western Africa.

 

 

As West Africa Ebola outbreak worsens, CDC issues Level 3 Travel Warning

CDC surge scaling up response in Guinea, Sierra Leone, and Liberia

The Centers for Disease Control and Prevention (CDC) today issued a warning to avoid nonessential travel to the West African nations of Guinea, Liberia, and Sierra Leone. This Level 3 travel warning is a reflection of the worsening Ebola outbreak in this region.

CDC is rapidly increasing its ongoing efforts in the three nations. CDC disease detectives and other staff are on the ground:

  • Tracking the epidemic including using real-time data to improve response
  • Improving case finding
  • Improving contact tracing
  • Improving infection control
  • Improving health communication
  • Advising embassies
  • Coordinating with the World Health Organization (WHO) and other partners
  • Strengthening Ministries of Health and helping them establish emergency management systems

“This is the biggest and most complex Ebola outbreak in history. Far too many lives have been lost already,” said CDC Director Tom Frieden, M.D., M.P.H. “It will take many months, and it won’t be easy, but Ebola can be stopped. We know what needs to be done. CDC is surging our response, sending 50 additional disease control experts to the region in the next 30 days.”

CDC expects its efforts not only to help bring the current outbreak under control, but to leave behind stronger systems to prevent, detect and stop Ebola and other outbreaks before they spread.

In addition to warning travelers to avoid going to the region, CDC is also assisting with active screening and education efforts on the ground in West Africa to prevent sick travelers from getting on planes. On the remote possibility that they do, CDC has protocols in place to protect against further spread of disease. These include notification to CDC of ill passengers on a plane before arrival, investigation of ill travelers, and, if necessary, quarantine. CDC also provides guidance to airlines for managing ill passengers and crew and for disinfecting aircraft. Earlier this week, CDC issued a Health Alert Notice reminding U.S. healthcare workers of the importance of taking steps to prevent the spread of this virus, how to test and isolate suspected patients and how they can protect themselves from infection.

At this time, CDC and its partners at points of entry are not screening passengers traveling from the affected countries. It is important to note that Ebola is not contagious until symptoms appear, and that transmission is through direct contact of bodily fluids of an infected, symptomatic person or exposure to objects like needles that have been contaminated with infected secretions.

Over the next five years the United States has committed to working with at least 30 partner countries (totaling at least 4 billion people) to improve their ability to prevent, detect, and effectively respond to infectious disease threats -- whether naturally occurring or caused by accidental or intentional release of pathogens.

Improving these capabilities for each nation improves health security for all nations. Stopping outbreaks where they occur is the most effective and least expensive way to protect people’s health.

The President’s FY 2015 budget includes a request of $45 million to fund this global health security effort.

Saturday, April 19, 2014

Saudi MOH Statement On Rise In Asymptomatic/Mild MERS Cases

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# 8497

 

With the understanding that whenever any government agency issues a statement, they do so with the intent of presenting their case in the best possible light, we get a report this morning from Sabq.org on a press conference held earlier today by the Saudi MOH.

 

One with a slightly different tone than we’ve seen before.

Perhaps feeling the sting of some of the recent commentary appearing in the International (see WaPo Editorial)  and Arabic press (see Criticism of the Saudi Ministry of Health in its dealings with Corona virus infections for a Dr. Ian Mackay Interview in Arabic), today’s statement seems to take the situation more seriously than in the past.


A few points worth noting:

 

  • The Saudi MOH is no longer calling the situation in Jeddah `normalor `stable
  • They acknowledge an increase in the number of MERS cases, and add that many are mild and/or asymptomatic
  • They state that they are expanding their testing for the virus
  • They are calling upon `all experts’ to lend assistance in dealing with this threat
  • And lastly, the MOH continues to dangle the prospect of developing a vaccine, even though any MERS vaccine is likely years away

 

Of course, we get the obligatory boiler-plate assertions of their `continuing policy transparency and openness’ in dealing with this situation, and admonitions not to listen to rumors, but rather to get your information directly from official sources.  A machine translated version follows:

"Health": the increase in the number of cases of Corona and the emergence of infected without symptoms

"الصحة": زيادة في عدد حالات كورونا وظهور مصابين بلا أعراض

Abdullah Al-barqawi.-Riyadh: the Saudi Health Ministry issued shortly before a press statement about the coronavirus, indicating which it observed an increase in the number of cases and the emergence of a number of cases without any symptoms.

The Ministry said in a statement that the continuation of its efforts, in order to identify the extent of coronavirus (Mers), the Ministry has expanded the work of the survey and research on the prevalence, screening large numbers of contacts where the Ministry has noted an increase in the number of cases and the emergence of a number of cases without any symptoms, thankfully.

The Ministry confirmed it is in constant contact with universities and scientific, manufacturers of vaccines for the access to the information with the rest of the world to learn the ways of HIV transmission and the possibility of treatment and access to an appropriate vaccine God's grace.

The Ministry has shown continuing policy transparency and openness will allow everyone access to any new information in this respect, at the same time calls upon everyone, not pandering rumors and information from unreliable sources and to get information about this virus from official sources.

The Ministry has invited all experts who have ideas or research projects regarding SK advance to the Scientific Committee national infectious diseases, Ministry of health, the Saudi universities to study the feasibility of such research and cooperation for their implementation.

Tuesday, March 25, 2014

PHAC Statement On The Saskatchewan Patient In Isolation

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Credit WHO

 

# 8401

 

Canada’s Public Health Agency has posted the following statement regarding the negative test findings on a `suspected’ imported case of Ebola in a person who had recently returned from Western Africa. 

 

Word of his negative results had been announced earlier today (see Crofsblog  Canada: Sick man in Saskatoon tests negative for Ebola, but we now have an `official statement’.

 

The cause of this person’s illness remains undetermined, but he has tested negative for the most worrisome types of viral hemorrhagic fever (Ebola, Marburg, Lassa, Crimean Congo Hemorrhagic Fever).

 

 

Statement from the Deputy Chief Public Health Officer

Saskatchewan Illness

Ottawa, ON

Last night, the Public Health Agency of Canada’s National Microbiology Laboratory confirmed that the patient in Saskatchewan does not have Ebola, Lassa, Marburg or Crimean Congo virus. Testing continues to diagnose the patient’s illness.

The risk to Canadians remains very low. In addition, the ruling out of those four hemorrhagic viruses significantly reduces the risk to the people who have been in close contact with the patient while the patient has exhibited symptoms.

To be clear, there are no confirmed cases of Ebola or any other hemorrhagic viruses in Canada. In fact, there has never been a confirmed case of a hemorrhagic virus in this country.

If a case were ever confirmed in Canada, the Public Health Agency of Canada would alert Canadians immediately and put measures in place to protect the public.

Thank you

Contacts

Michael Bolkenius
Office of the Honourable Rona Ambrose
Federal Minister of Health
(613) 957-0200

Media Relations
Public Health Agency of Canada
(613) 957-2983

 

Public Health Canada also released this travel advisory on the Ebola outbreak in Western Africa yesterday.

 

Ebola Outbreak in Guinea

Released: March 24, 2014

Travel Health Notice

The Ministry of Health of Guinea has notified the World Health Organization (WHO) of a rapidly evolving outbreak of Ebola haemorrhagic fever in forested areas in south eastern Guinea. As of March 22, 2014, a total of 49 cases have been reported, of which 29 were fatal.

Cases have been reported in Guekedou, Macenta, Nzerekore and Kissidougou districts. In addition, in Conakry three suspected cases, including two deaths, are under investigation. Four health care workers are among the victims. Reports of suspected cases in border areas of Liberia and Sierra Leone are being investigated.

The Ministry of Health of Guinea together with the WHO and other partners have initiated measures to control the outbreak and prevent further spread. WHO does not recommend that any travel or trade restrictions be applied to Guinea in relation to this outbreak.

Ebola haemorrhagic fever is a rare and severe viral disease. The virus can infect both humans and non-human primates (monkeys, gorillas, etc.). When infected, people can get very sick, with fever and pains, and may bleed from different parts of the body (i.e., haemorrhage).

Although the risk is low for most travellers, the Public Health Agency of Canada recommends travellers in Guinea avoid direct contact with blood or bodily fluids of a person or corpse infected with the Ebola virus. Also, avoid contact with or handling an animal suspected of having Ebola haemorrhagic fever.

Recommendations

Consult a health care provider or visit a travel health clinic at least six weeks before you travel.

  1. Avoid direct contact with blood and other bodily fluids of people with Ebola haemorrhagic fever or unknown illnesses.
    • Avoid direct contact with bodies of people who died of Ebola haemorrhagic fever or unknown illnesses.
    • Avoid unprotected sexual intercourse with an infected person or a person recovering from Ebola haemorrhagic fever.
    • Avoid contact with any objects, such as needles, that have been contaminated with blood or bodily fluids.
    • Health care workers should practise strict infection control measures including the use of personal protective equipment (i.e., gowns, masks, goggles and gloves).
  2. Avoid close contact with or handling of wild animals.
    • The following animals may be carriers: chimpanzees, gorillas, monkeys, forest antelope, pigs, porcupines, duikers and fruit bats.
    • Remember, both live and dead animals can spread the virus.
    • Avoid handling wild meat.
  3. Know the symptoms of Ebola haemorrhagic fever and see a health care provider if they develop.
    • Seek medical attention immediately, if a fever and any other symptoms arise during or after travel.
    • Be sure to tell your healthcare provider that you have travelled to a region where Ebola haemorrhagic fever was present.

Tuesday, March 11, 2014

Cambodia: Statement On 7th & 8th H5N1 Cases Of 2014

Photo Credit - Ministry of Health of the Kingdom of Cambodia

 

 

# 8364

 

Although it has yet to appear on the Cambodian MOH website, overnight the United Nations in Cambodia posted the following Joint Press Release From the Ministry of Health, Kingdom of Cambodia, and the World Health Organization (WHO) on the two H5N1 cases widely reported in the media Sunday night (see Cambodia: Media Reports Two New H5N1 Cases (1 Fatal)).

 

7th and 8th New Human Cases of Avian Influenza H5N1 in Cambodia in 2014
 

Joint Press Release From the Ministry of Health, Kingdom of Cambodia, and the World Health Organization (WHO)

Phnom Penh, 11 March 2014

The Ministry of Health (MoH) of the Kingdom of Cambodia wishes to advise members of the public that two (2) new human cases of avian influenza have been confirmed for the H5N1 virus. This is the 7th and 8th cases this year and the 54th and 55th persons to become infected with the H5N1 virus in Cambodia. The cases are from Kandal and Kampong Chnnang provinces. Of the 55 confirmed cases, 43 were children under 14, and 29 of the 55 were female. In addition, since the first case happened in Cambodia in 2005 there were 19 cases survived.

The 7th case, an 8-year-old boy from Spean-Dek village, Prek-TunLoab commune, Leuk-Dek district, Kandal province, was tested positive by Institut Pasteur du Cambodge on the 6th March 2014. The boy had onset symptoms of fever, chill, running nose, sore throat, and cough on 24th February 2014. His parents sought treatment at a private practitioner in the village on the same day. His condition worsened and the boy was admitted to Kantha Bopha Hospital on 4th March. On 4th March, the boy had symptoms of fever, chill, running nose, sore throat, cough, dyspnoea, convulsion and somnolence. The specimen was collected on 5th March and Tamiflu was administered on the same day. The boy is recovering.

Around mid-February, about 90% of poultries died in the village. Chickens died in the case’s house and the family buried them. There is also a poultry slaughter’s house near to the case’s house. The parents reported that the boy had no direct contact but the chickens died in close proximity.

The 8th case, an 11-year-old boy from Toeuk Laak village, Toeuk Haut commune, Rolea Paear district, Kampong Chnnang province, was tested positive by Institut Pasteur du Cambodge on the 6th March 2014. The boy had onset symptoms of fever and headache on 3rd March 2014. His parents sought treatment at a private practitioner next to their house on the same day and on the next day (4th March). His condition worsened and the boy was admitted to Kampong Chnnang Provincial Hospital on 5th March. On 6th March, the boy had symptoms of fever, cough, and shortness of breath and was referred to Kantha Bopha Hospital in the afternoon on the same day. The boy died a few hours after his admission on 6th March.

Beginning of February, chickens started dying in the village and in the case’s house and continued for a month. The boy helped to prepare dead chickens and ducks for food and ate them.

The Ministry of Health’s​ National and local Rapid Response Teams (RRTs) are conducting outbreak investigation and responses following the national protocol.

(Continue . . . )

 

This statement also includes details on their ongoing public education campaign on H5N1 safety, promoting the messages  - wash hands often with soap and water, before eating and after coming into contact with poultry; keep children away from poultry; keep poultry away from living areas; do not eat dead or sick poultry; and all poultry eaten should be well cooked.

It also updates the MOH’s statement on the dangers of H5N1:

"Avian influenza H5N1 remains a serious threat to the health of all Cambodians and more so for children, who seem to be most vulnerable and are at high risk. There have been 55 cases of H5N1 infection in humans since 2005 and here are the seventh and eight cases of this year. Children often care for domestic poultry by feeding them, cleaning pens and gathering eggs. Children may also have closer contact with poultry as they often treat them as pets and also seem to be most vulnerable and are at high risk because they like to play where poultry are found. I urge parents and guardians to keep children away from sick or dead poultry and prevent them from playing with chickens and ducks. Parents and guardians must also make sure children thoroughly wash their hands with soap and water before eating and after any contact with poultry. Hands may carry the virus that cannot be seen by the naked eye. Soap washes away the virus on hands. If children have fast or difficult breathing, their parents should seek medical attention at the nearest health facility and attending physicians must be made aware of any exposure to sick or dead poultry,” said H.E. Dr. Mam Bunheng, Minister of Health.

 

 

Although we’ve seen 45 cases reported in Cambodia since this uptick began three years ago (see 2011’s Cambodia’s Bird Flu Risk "under control" – Experts), they continue to emerge sporadically, and from numerous and widespread provinces across the country. 

 

We’ve seen a few clusters (see Cambodia: 2 Deaths - 1 Confirmed H5N1, 1 Probable), but no signs of sustained or efficient human-to-human transmission. 

 

By the same token, the fact that the virus has been acquired (presumably from infected chickens & ducks) across wide swaths of their nation in recent years speaks to how prevalent the virus apparently has become in Cambodia’s poultry. 

 

While renewed public awareness campaigns have been mounted, that message is likely lost on a population to whom hunger, malaria, dengue, and diarrheal diseases take a much greater toll.  Add in rising food prices and growing food insecurity, and the odds that families follow the government’s advice to `not eat dead or sick poultry’ is probably pretty low.

 

The good news, so far at least, is that the H5N1 bird flu virus remains primarily an avian-adapted virus.  It only rarely infects humans, and human-to-human transmission is even rarer still.

 

As with H7N9, H10N8, H9N2 (and a short list of other novel flu viruses)  the concern remains that given enough opportunities, one of these viruses might better adapt to human physiology and someday pose a pandemic threat.

Thursday, January 09, 2014

CDC Statement On 1st H5N1 Case In North America

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Global H5N1 cases & Deaths - Credit CDC

 

# 8149

 

Although the risk of seeing additional avian flu cases in Canada (or the United States) as a result of yesterday’s announced H5N1 fatality in Alberta, Canada is considered low, the CDC released the following lengthy and informative statement last night on this case, including a good deal of background on avian flu viruses.

 

 

First Human Avian Influenza A (H5N1) Virus Infection Reported in Americas

January 8, 2014 – Canada has reported the first case of human infection with avian influenza A (H5N1) virus ever detected in the Americas. The case occurred in a traveler who had recently returned from China. H5N1 virus infections are rare and these viruses do not spread easily from person to person. Most of the 648 human cases of H5N1 infections that have been detected since 2003 have occurred in people with direct or close contact with poultry. The Centers for Disease Control and Prevention (CDC) considers that the health risk to people in the Americas posed by the detection of this one case is very low. CDC is not recommending that the public take any special actions regarding H5N1 virus in response to this case. For people traveling to China, CDC recommends that people take the same protective actions against H5N1 as recommended to protect against H7N9 or other avian influenza A viruses. This information is available on the CDC website at Travelers Health: Avian Flu (Bird Flu).

 

According to Canadian health officials, the patient, who died on January 4, 2014, recently traveled to Beijing, China, where avian influenza A H5N1 is endemic among poultry. This is the first detected case of human infection with avian influenza A H5N1 virus in North or South America. It also is the first case of H5N1 infection ever imported by a traveler into a country where this virus is not present in poultry. No such H5N1 viruses have been detected in people or in animals in the United States.

 

While human infection is rare, it often results in serious illness with very high mortality (60%). CDC has recommended enhanced surveillance measures to detect possible cases of H5N1 in this country since 2003. In 2007, “novel influenza A infections” such as H5N1, became nationally notifiable diseases in the United States. Novel influenza A virus infections include all human infections with influenza A viruses that are different from currently circulating human seasonal influenza H1 and H3 viruses. Rapid reporting of human infections with novel influenza A viruses facilitates prompt detection and characterization of influenza A viruses and accelerates the implementation of effective public health responses.

 

While the current risk from H5N1 viruses is very low and CDC believes it unlikely that cases of H5N1 have occurred in the United States, CDC will send out a reminder to clinicians in this country about when and how to test for H5N1 infection. The recommendations for testing for H5N1 are similar to those for H7N9 and include recent travel (within 10 days) to a country with H5N1 virus infections in birds or people. The guidance for H7N9 is posted on the CDC website at Human Infections with Novel Influenza A (H7N9) Viruses.

 

According to CDC, more concerning for Americans right now is seasonal flu, which is widespread in much of the country. The agency urges people who have not gotten their seasonal flu vaccine this season to get vaccinated now. A seasonal vaccine will protect you against seasonal flu viruses.

 

As mentioned previously, avian influenza A H5N1 is endemic in poultry in China. Since 2003, 45 cases of human infection with H5N1 have been reported in China and 30 (67%) have died. Affected persons have ranged in age from 2 years to 62 years, with an average age of 26 years. Most of the reported cases have had poultry exposure.

 

The detection of one isolated case of H5N1 virus infection in a returned traveler does not change the current risk assessment for an H5N1 pandemic. A pandemic would only result if the H5N1 virus were to gain the ability to spread efficiently from person-to-person and there is no indication that this has occurred.

 

CDC is in close contact with Canadian public health partners and has offered laboratory and other support as needed. The agency will continue to monitor this situation closely and work with public health partners to rapidly test any incoming specimens and advise local and state authorities regarding control measures if needed. Long-term preparedness measures against H5N1 include the existence of a stockpile of H5N1 vaccine in the Strategic National Stockpile.

(Continue . . . )

Wednesday, January 08, 2014

HK CHP Statement On Third (likely) Imported H7N9 Case

image

 


# 8141

 

The story has been buzzing around for several hours (see here, and here), but we now have an official statement from Hong Kong’s Centre for Health Protection on what appears to be that city’s third imported case of H7N9.  This is also the third H7N9 case announced today, with 1 case reported in Guangdong province, and another in Jiangsu province.

 

Third confirmed human case of avian influenza A(H7N9) in Hong Kong under CHP investigation

The Centre for Health Protection (CHP) of the Department of Health (DH) is today (January 8) investigating an additional confirmed human case of avian influenza A(H7N9) in Hong Kong affecting a man aged 65.

The patient, with underlying medical condition, lives in Sham Shui Po. He presented with fever, coughing and shortness of breath since January 3 and attended the Accident and Emergency Department of Queen Mary Hospital (QMH) on January 7. He was admitted for chest infection. As his condition deteriorated, he was transferred to the Intensive Care Unit on the same day.

His nasopharyngeal aspirate tested positive for avian influenza A(H7N9) virus upon laboratory testing by the Public Health Laboratory Services Branch of the CHP today.

The patient is currently under isolation for further management in QMH in critical condition.

Initial investigation by the CHP revealed that the patient had travelled to Shenzhen with his family member from January 1 to 2. They passed by a wet market in Shenzhen on January 1. In Hong Kong, the patient did not go into wet markets, but he may sometimes walk pass the entrance of Pei Ho Street Market in Sham Shui Po in the morning.

Enquiries also indicated that his close contact has remained asymptomatic so far and will be put under quarantine for 10 days since last contact with the patient. Contact tracing for his other contacts including patients in QMH who stayed in the same cubicle with the confirmed patient as well as healthcare workers in QMH and relevant hospital visitors are underway. They will be put under medical surveillance.


This is the third confirmed human case of avian influenza A(H7N9) in Hong Kong.

(Continue . . . )

 

Exactly where this patient contracted the virus is uncertain, but he did have recent travel history to Shenzhen, where two other imported cases in December had traveled, and where local infections have recently been reported.

 

Despite this uptick in H7N9 case reports, none of these cases are epidemiologically linked, we’ve seen no signs of secondary infection in their contacts, and so far we’ve no evidence to suggest efficient or sustained human-to-human transmission of the virus.